Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : NKTR-255,C-TIL051
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Nektar Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration will evaluate Nektar's NKTR-255, a novel IL-15 receptor agonist, in combination with CBMG's C-TIL051, a tumor-infiltrating lymphocyte (TIL) therapy, in advanced non-small cell lung cancer (NSCLC) patients that are relapsed or refractory...
Brand Name : NKTR-255
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 27, 2023
Lead Product(s) : NKTR-255,C-TIL051
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Nektar Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Prizloncabtagene Autoleucel
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Johnson & Johnson Innovative Medicine
Deal Size : $245.0 million
Deal Type : Collaboration
Details : Through the collaboration, Janssen enhances its portfolio in B-cell malignancies and strengthens its legacy in hematology, by including C-CAR039 (prizloncabtagene autoleucel), a novel bispecific CAR-T therapy targeting both CD19 and CD20 antigens for the...
Brand Name : C-CAR039
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
May 02, 2023
Lead Product(s) : Prizloncabtagene Autoleucel
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Johnson & Johnson Innovative Medicine
Deal Size : $245.0 million
Deal Type : Collaboration
CBMG Receives FDA Regenerative Medicine Advanced Therapy and Fast Track Designations
Details : FDA has granted C-CAR039 both RMAT and FTD, based on the result that showed overall response rate of 92.6%, and a complete response rate of 85.2% in relapsed or refractory diffuse large B cell lymphoma.
Brand Name : EXP039
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
January 12, 2022
Details : C-CAR039, an autologous bi-specific CAR-T cell therapy targeting both CD19/CD20 for treatment in adult patients with relapsed/refractory B-cell non-Hodgkin lymphomas. Clinical study results from an ongoing multicenter trial conducted in China have shown ...
Brand Name : EXP039
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 16, 2021
Details : The financing will largely be used to accelerate the clinical development of the Company's immune-oncology platform specifically, C-CAR039, an anti-CD19/CD20 bispecific CAR-T therapy for the treatment of patients with relapsed or refractory non-Hodgkin l...
Brand Name : EXP039
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 30, 2021
CBMG' Novel Anti-CD20 CAR-T Cell Therapy Shows Promising Safety and Efficacy
Details : C-CAR066, a novel second generation chimeric antigen receptor T (CAR-T) therapy targeting CD20 antigen in relapsed/refractory B-cell non-Hodgkin lymphoma (r/r B-NHL) that has failed to an anti-CD19 CAR-T therapy.
Brand Name : C-CAR066
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 10, 2021
Details : C-TCR055 is CBMG's proprietary clinical lead of TCR-T which specifically recognizes the HLA-A*02:01 restricted AFP158-166 peptide that is highly expressed in hepatocellular carcinoma (HCC) and other solid tumors.
Brand Name : C-TCR055
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 22, 2020
Lead Product(s) : Mesenchymal stem cell exosomes
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Cellular has started to collaborate with Shanghai Ruijin Hospital on a pilot clinical study on inhalation of mesenchymal stem cell exosomes treating severe Novel Coronavirus Pneumonia.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 28, 2020
Lead Product(s) : Mesenchymal stem cell exosomes
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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