Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : PDA-002
Therapeutic Area : Musculoskeletal
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Celularity Requests U.S. FDA ODD for PDA-002 in Muscular Dystrophy Treatment
Details : PDA-002 is a placenta-derived mesenchymal-like adherent stromal cell therapy, which is being evaluated for the treatment of facioscapulohumeral muscular dystrophy.
Brand Name : PDA-002
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
March 20, 2024
Lead Product(s) : PDA-002
Therapeutic Area : Musculoskeletal
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Human Amniotic Membrane
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Biovance, a decellularized, dehydrated human amniotic membrane derived from the placenta of a healthy, full-term pregnancy. Biovance is an intact, extracellular matrix structure that provides a natural scaffold to support the body’s wound-healing proce...
Brand Name : Biovance
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
October 18, 2023
Lead Product(s) : Human Amniotic Membrane
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Allogeneic Cell Therapy
Therapeutic Area : Oncology
Study Phase : Discovery
Sponsor : Regeneron Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Celularity Announces Multi-Year Research Collaboration Services Agreement with Regeneron
Details : Under the collaboration, Celularity will provide research support for Regeneron's targeted, allogeneic, chimeric antigen receptor (CAR) T-cell therapy, designed to enhance proliferation and potency against solid tumors.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
August 29, 2023
Lead Product(s) : Allogeneic Cell Therapy
Therapeutic Area : Oncology
Highest Development Status : Discovery
Sponsor : Regeneron Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Details : CYNK-001 is a cryopreserved, allogeneic, off-the-shelf, natural killer (NK) cell therapy candidate derived from placental hematopoietic stem cells as a potential treatment option for various hematologic cancers, solid tumors, and infectious disease.
Brand Name : CYNK-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 27, 2023
Lead Product(s) : APPL-001
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : APPL-001 is a placental-derived allogeneic cell therapy, being developed for the treatment of Crohn's disease. The optimal MLASC treatment schedule is identified to be a single treatment course of two infusions seven days apart, with no further maintenan...
Brand Name : APPL-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
January 06, 2023
Lead Product(s) : APPL-001
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CYNK-101,Avelumab
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CYNK-101 is a cryopreserved, off-the-shelf, allogeneic, placental CD34+ derived NK cell therapy, overexpressing a high IgG binding affinity, proteinase cleavage resistant, CD16 variant.
Brand Name : CYNK-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 10, 2022
Lead Product(s) : CYNK-101,Avelumab
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CYNK-001
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CYNK-001 is an allogeneic placental-derived unmodified NK cell. CYNK-001 may offer a benefit to patients with IAV and other viral infections, including its use a treatment for infectious disease for patients with limited treatment options.
Brand Name : CYNK-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 26, 2022
Lead Product(s) : CYNK-001
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CYNK-001,Undisclosed,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : YA II PN
Deal Size : $150.0 million
Deal Type : Agreement
Celularity Enters Into $150 Million Pre-Paid Advance Agreement with Yorkville
Details : Celularity intends to use the proceeds for general corporate purposes may include research and development and clinical development costs to support the development of its cellular therapy candidate, CYNK-001 and the expansion of research and development...
Brand Name : CYNK-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 15, 2022
Lead Product(s) : CYNK-001,Undisclosed,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : YA II PN
Deal Size : $150.0 million
Deal Type : Agreement
Lead Product(s) : CYNK-101,Trastuzumab,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Phase 1/2a clinical trial, evaluate safety and preliminary efficacy of CYNK-101, genetically modified NK cell therapy in combination with standard chemotherapy, trastuzumab and pembrolizumab as a first-line treatment in advanced HER2/neu positive gastric...
Brand Name : CYNK-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 15, 2022
Lead Product(s) : CYNK-101,Trastuzumab,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : USFDA granted Fast Track Designation for its cryopreserved human placental hematopoietic stem cell-derived natural killer cell therapy, CYNK-001, in treatment of acute myeloid leukemia. CYNK-001 previously received orphan drug designation and fast track ...
Brand Name : CYNK-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 27, 2021
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