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Find Clinical Drug Pipeline Developments & Deals for Cemiplimab

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Study Phase : Approved

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : $1,100.0 million

                          Deal Type : Acquisition

                          Details : Regeneron intends to update its full year 2022 financial guidance to reflect the Libtayo (cemiplimab) purchase during its second quarter 2022 earnings announcement in early August.

                          Brand Name : Libtayo

                          Molecule Type : Large molecule

                          Upfront Cash : $900.0 million

                          July 01, 2022

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : $1,100.0 million

                          Deal Type : Acquisition

                          Sanofi Company Banner

                          02

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Study Phase : Approved

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : $1,100.0 million

                          Deal Type : Collaboration

                          Details : Under the terms announced today, Sanofi will transfer the rights to develop, commercialize and manufacture Libtayo (cemiplimab) entirely to Regeneron, on a worldwide basis, over the course of a defined transition period.

                          Brand Name : Libtayo

                          Molecule Type : Large molecule

                          Upfront Cash : $900.0 million

                          June 02, 2022

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : $1,100.0 million

                          Deal Type : Collaboration

                          Sanofi Company Banner

                          03

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Study Phase : Phase III

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Libtayo is a fully human monoclonal antibody targeting the immune checkpoint receptor PD-1 on T-cells. By binding to PD-1, Libtayo has been shown to block cancer cells from using the PD-1 pathway to suppress T-cell activation.

                          Brand Name : Libtayo

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          January 28, 2022

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Sanofi Company Banner

                          04

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Study Phase : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : In the Phase 3 trial, safety was assessed in 697 patients, with a duration of exposure of 27 weeks (range: 9 days to 115 weeks) for the Libtayo group and 18 weeks (range: 18 days to 87 weeks) for the chemotherapy group.

                          Brand Name : Libtayo

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 25, 2021

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Sanofi Company Banner

                          05

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Study Phase : Phase III

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : In Phase 3 trial, Libtayo, a fully human monoclonal antibody targeting the immune checkpoint receptor PD-1, significantly improved overall survival in women with advanced cervical cancer after progression on chemotherapy, lowering the risk of death by 31...

                          Brand Name : Libtayo

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 12, 2021

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Sanofi Company Banner

                          06

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Study Phase : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Protocol-specified interim analysis conducted by the Independent Data Monitoring Committee demonstrated that patients treated with Libtayo monotherapy had a significant increase in overall survival.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 27, 2020

                          Lead Product(s) : Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Sanofi Company Banner

                          07

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : The net proceeds from the offering will be used to fund THIO-101 (6-Thio-2-Deoxyguanosine), which is currently undergoing mid-stage trials for the treatment of non-small cell lung cancer.

                          Brand Name : THIO-101

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 28, 2024

                          Lead Product(s) : 6-Thio-2-Deoxyguanosine,Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : $2.4 million

                          Deal Type : Private Placement

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                          08

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : THIO-101 (6-Thio-2-Deoxyguanosine) is a telomere-targeting agent currently in clinical development in combination with cemiplimab for non-small cell lung cancer.

                          Brand Name : THIO-101

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 10, 2024

                          Lead Product(s) : 6-Thio-2-Deoxyguanosine,Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : BNT111 is an mRNA-based off-the-shelf cancer immunotherapy candidate. It is being evaluated for the treatment of patients with unresectable stage III or IV melanoma.

                          Brand Name : BNT111

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          July 30, 2024

                          Lead Product(s) : BNT111,Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : THIO-101 (6-Thio-2-Deoxyguanosine) is a telomere-targeting agent currently in clinical development in combination with cemiplimab for non-small cell lung cancer.

                          Brand Name : THIO-101

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 04, 2024

                          Lead Product(s) : 6-Thio-2-Deoxyguanosine,Cemiplimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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