Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
XCOPRI Gets FDA Approval for Alternate Methods of Oral or Nasogastric Administration
Details : Xcopri (cenobamate), is an antiseizure medication (ASM) for adults with partial-onset (focal) seizures, is now approved as oral suspension or can be administered via a nasogastric tube.
Brand Name : Xcopri
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 11, 2024
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Endo's Paladin Labs Announces Launch of XCOPRI® (cenobamate tablets) in Canada
Details : Xcopri (cenobamate) is a positive allosteric modulator of the GABAA ion channel. It is approved as adjunctive therapy in the management of partial-onset seizures in adults with epilepsy.
Brand Name : Xcopri
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 22, 2024
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Hikma Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Korea's SK Biopharma Enters MENA Through Strategic Partnership with Hikma
Details : Under the terms of the agreement, Hikma will have priority rights for the commercialisation and manufacture of SK Biopharmaceuticals’ current and future pipeline of innovative products for 17 countries in the MENA region.
Brand Name : Xcopri
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 21, 2023
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Hikma Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Endo Announces Approval of XCOPRI (cenobamate tablets) in Canada
Details : XCOPRI™ (cenobamate tablets) inhibiting voltage-gated sodium currents. It is also a positive allosteric modulator of the γ-aminobutyric acid (GABAA) ion channel, which is used for partial-onset seizures in adults with epilepsy.
Brand Name : Xcopri
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 29, 2023
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Angelini Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
SK Biopharmaceuticals' Partner Angelini Pharma Launches Cenobamate in France
Details : Cenobamate – under the brand name ONTOZRY® – has been commercialized in five major European countries such as Germany, the UK, Italy, Spain, and France, accounting for about 73 percent of the total value of the continent’s epilepsy market.
Brand Name : Ontozry
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 09, 2022
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Angelini Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Ontozry (cenobamate) is a novel small molecule that provides a dual, complementary mechanism of action aimed at treatment of seizures also known as focal-onset seizures.
Brand Name : Ontozry
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 07, 2022
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Eurofarma Laboratorios S.A
Deal Size : $62.0 million
Deal Type : Licensing Agreement
SK Biopharmaceuticals, Eurofarma Enter into Licensing Agreement for Cenobamate in Latin America
Details : Under the terms of agreement, SK Biopharmaceuticals has granted Eurofarma the exclusive rights to develop and commercialize Xcopri (cenobamate) in Latin America. SK Biopharmaceuticals will now be present in four continents: North America, Europe, Asia, a...
Brand Name : Xcopri
Molecule Type : Small molecule
Upfront Cash : $15.0 million
July 14, 2022
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Eurofarma Laboratorios S.A
Deal Size : $62.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Long-Term Efficacy and Safety Data of XCOPRI® (cenobamate tablets) CV Published in Neurology
Details : The open-label extension of Study C017 demonstrated high response rates with no new safety signals identified in patients receiving XCOPRI (cenobamate) for up to 4 years.
Brand Name : Xcopri
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 22, 2022
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Pivotal trial has demonstrated that Ontozry (cenobamate) at doses of 100 mg, 200 mg, and 400 mg/day significantly improved seizure control versus placebo for adult patients with focal-onset seizures taking 1-3 ASMs.
Brand Name : Ontozry
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 01, 2022
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : XCOPRI® (cenobamate tablets) CV, is an anti-seizure medication (ASM), a positive allosteric modulator of the γ-aminobutyric acid (GABAA) ion channel believed to reduce repetitive neuronal firing by inhibiting voltage-gated sodium currents.
Brand Name : Xcopri
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 24, 2022
Lead Product(s) : Cenobamate
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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