Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : CNTY-101
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Century Announces Phase 1/2 Trial of iNK Cell Therapy CNTY-101 in Autoimmune Diseases
Details : CNTY-101, targeting CD19 for relapsed, refractory B-cell lymphoma, is an allogeneic, iPSC-derived CAR-iNK cell therapy, intended for moderate to severe systemic lupus erythematosus.
Product Name : CNTY-101
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
January 21, 2025
Lead Product(s) : CNTY-101
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CNTY-101
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Bain Capital Life Sciences
Deal Size : $60.0 million
Deal Type : Private Placement
Century Therapeutics Expands Autoimmune Pipeline Supported by $60M and Clade Acquisition
Details : Century intends to use the net proceeds to support the expansion of CNTY-101, a CD19-targeting iNK cell therapy, currently being evaluated in a clinical trial in B-cell malignancies.
Product Name : CNTY-101
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
November 04, 2024
Lead Product(s) : CNTY-101
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Bain Capital Life Sciences
Deal Size : $60.0 million
Deal Type : Private Placement
Details : CNTY-101 is an investigational off-the-shelf cancer immunotherapy product candidate that utilizes iPSC-derived NK cells with a CD19-directed CAR and designed to overcome the three major pathways of host versus graft rejection - CD8+ T cells, CD4+ T cells...
Product Name : CNTY-101
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
August 02, 2023
Lead Product(s) : CNTY-101
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CNTY-101, targeting CD19 for relapsed, refractory B-cell lymphoma, is an allogeneic, iPSC-derived CAR-iNK cell therapy, administered via Intravenous Infusion, intended for moderate to severe systemic lupus erythematosus.
Product Name : CNTY-101
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
June 12, 2023
Lead Product(s) : CNTY-101
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Century will be responsible for discovery and preclinical development of CNTY-104, an iPSC-derived allogeneic cell therapies for hematologic and solid tumors. Bristol Myers Squibb will be responsible for clinical development and commercialization of firs...
Product Name : CNTY-104
Product Type : Cell and Gene therapy
Upfront Cash : $150.0 million
October 01, 2022
Details : CNTY-101 is the first allogeneic cell product candidate with six genetic modifications incorporated using sequential rounds of CRISPR-mediated homologous recombination and repair that has received IND clearance by the FDA.
Product Name : CNTY-101
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
August 25, 2022
Century Therapeutics to Present at the SITC 37th Annual Meeting
Details : CNTY-101, targeting CD19 for relapsed, refractory B-cell lymphoma, is an allogeneic, iPSC-derived CAR-iNK cell therapy that has been engineered to express CD19 CAR, soluble IL-15, and an EGFR safety switch.
Product Name : CNTY-101
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
May 10, 2022
Lead Product(s) : CNTY-102
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Century Therapeutics to Present at the ASGCT 25th Annual Meeting
Details : CNTY-102 simultaneously target CD19 and CD79b designed to increase depth and durability of response by eliminating effect of CD19 antigen loss that has been observed as factor limiting treatment durability while targeting CD79b.
Product Name : CNTY-102
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 05, 2022
Lead Product(s) : CNTY-102
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable