Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : CNTY-101
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Bain Capital Life Sciences
Deal Size : $60.0 million
Deal Type : Private Placement
Century Therapeutics Expands Autoimmune Pipeline Supported by $60M and Clade Acquisition
Details : Century intends to use the net proceeds to support the expansion of CNTY-101, a CD19-targeting iNK cell therapy, currently being evaluated in a clinical trial in B-cell malignancies.
Brand Name : CNTY-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 11, 2024
Lead Product(s) : CNTY-101
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Bain Capital Life Sciences
Deal Size : $60.0 million
Deal Type : Private Placement
Lead Product(s) : iPSC-derived Cell Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Clade Therapeutics
Deal Size : $45.0 million
Deal Type : Acquisition
Century Therapeutics Strengthens Position in Autoimmune with Pipeline Expansion
Details : Acquisition of Clade Therapeutics strengthens Century’s position as a leader in allogeneic, iPSC-derived cell therapy through enhancement of pipeline and next generation Allo-EvasionTM platform.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : $45.0 million
April 11, 2024
Lead Product(s) : iPSC-derived Cell Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Clade Therapeutics
Deal Size : $45.0 million
Deal Type : Acquisition
Lead Product(s) : CNTY-101
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CNTY-101, targeting CD19 for relapsed, refractory B-cell lymphoma, is an allogeneic, iPSC-derived CAR-iNK cell therapy, administered via Intravenous Infusion, intended for moderate to severe systemic lupus erythematosus.
Brand Name : CNTY-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 06, 2023
Lead Product(s) : CNTY-101
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : iPSC-derived Cell Therpay
Therapeutic Area : Endocrinology
Study Phase : Discovery
Recipient : Fujifilm Cellular Dynamics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : The agreement aims for the development and commercialization of cell therapies derived from iPSCs for the treatment of autoimmune and inflammatory diseases, including type 1 diabetes, multiple sclerosis, lupus, and rheumatoid arthritis.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
November 09, 2023
Lead Product(s) : iPSC-derived Cell Therpay
Therapeutic Area : Endocrinology
Highest Development Status : Discovery
Recipient : Fujifilm Cellular Dynamics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : CNTY-101 is an investigational off-the-shelf cancer immunotherapy product candidate that utilizes iPSC-derived NK cells with a CD19-directed CAR and designed to overcome the three major pathways of host versus graft rejection - CD8+ T cells, CD4+ T cells...
Brand Name : CNTY-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 08, 2023
Century Therapeutics to Present at the SITC 37th Annual Meeting
Details : CNTY-101, targeting CD19 for relapsed, refractory B-cell lymphoma, is an allogeneic, iPSC-derived CAR-iNK cell therapy that has been engineered to express CD19 CAR, soluble IL-15, and an EGFR safety switch.
Brand Name : CNTY-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
October 05, 2022
Details : CNTY-101 is the first allogeneic cell product candidate with six genetic modifications incorporated using sequential rounds of CRISPR-mediated homologous recombination and repair that has received IND clearance by the FDA.
Brand Name : CNTY-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
August 25, 2022
Lead Product(s) : CNTY-102
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Century Therapeutics to Present at the ASGCT 25th Annual Meeting
Details : CNTY-102 simultaneously target CD19 and CD79b designed to increase depth and durability of response by eliminating effect of CD19 antigen loss that has been observed as factor limiting treatment durability while targeting CD79b.
Brand Name : CNTY-102
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
May 02, 2022
Lead Product(s) : CNTY-102
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CNTY-104
Therapeutic Area : Oncology
Study Phase : Discovery
Sponsor : Bristol Myers Squibb
Deal Size : $3,150.0 million
Deal Type : Collaboration
Details : Century will be responsible for discovery and preclinical development of CNTY-104, an iPSC-derived allogeneic cell therapies for hematologic and solid tumors. Bristol Myers Squibb will be responsible for clinical development and commercialization of firs...
Brand Name : CNTY-104
Molecule Type : Cell and Gene therapy
Upfront Cash : $150.0 million
January 10, 2022
Lead Product(s) : CNTY-104
Therapeutic Area : Oncology
Highest Development Status : Discovery
Sponsor : Bristol Myers Squibb
Deal Size : $3,150.0 million
Deal Type : Collaboration
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