Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AEVI-002
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Grants Fast Track Designation to CERC-002 for Treatment of Hospitalized Patients with COVID-19
Details : CERC-002 is a first-in-class fully human monoclonal antibody targeting LIGHT (tumor necrosis factor superfamily member 14, TNFSF14).
Product Name : CERC-002
Product Type : Antibody
Upfront Cash : Inapplicable
November 05, 2021
Lead Product(s) : AEVI-002
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AEVI-002
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cerecor Positive Initial Phase CERC-002 in Moderate to Severe Crohn's Disease
Details : The study is a pilot study using a dose-escalation design to characterize the safety and tolerability of two different doses of CERC-002 (1.0 mg/kg and 3.0 mg/kg).
Product Name : CERC-002
Product Type : Antibody
Upfront Cash : Inapplicable
July 26, 2021
Lead Product(s) : AEVI-002
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AEVI-007
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CERC-007 is a high affinity, fully human anti-IL-18 monoclonal antibody (mAb). IL-18 has been demonstrated to have a key role as a marker of disease activity and its concentration correlates with disease severity in AOSD patients.
Product Name : CERC-007
Product Type : Antibody
Upfront Cash : Inapplicable
May 05, 2021
Lead Product(s) : AEVI-007
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CERC-002
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cerecor Announces Successful Proof of Concept Data for CERC-002
Details : COVID-19 ARDS patients treated with a single dose of the anti-LIGHT monoclonal antibody CERC-002 demonstrated robust improvement in the primary endpoint (proportion of patients alive and free of respiratory failure over the 28-day study period) compared ...
Product Name : AEVI-002
Product Type : Antibody
Upfront Cash : Inapplicable
May 01, 2021
Lead Product(s) : CERC-002
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AEVI-002
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Horizon Technology Finance Corporation
Deal Size : Undisclosed
Deal Type : Financing
Details : This second tranche is in connection with the Company’s successful positive initial results from a Phase 1b proof-of-concept study evaluating CERC-002, an investigational first-in-class fully human anti-LIGHT monoclonal antibody for moderate- to-severe...
Product Name : CERC-002
Product Type : Antibody
Upfront Cash : Undisclosed
February 08, 2021
Lead Product(s) : AEVI-002
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Horizon Technology Finance Corporation
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : CERC-002
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Cerecor has resumed the Phase 1b clinical study of CERC-002 in anti-TNF refractory adult Crohn’s patients with the lifting of the moratorium on elective endoscopy resulting from the COVID-19 pandemic.
Product Name : AEVI-002
Product Type : Antibody
Upfront Cash : Inapplicable
August 26, 2020
Lead Product(s) : CERC-002
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CERC-002
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Publication supports Cerecor clinical program evaluating CERC-002, the only clinical stage anti-LIGHT monoclonal antibody, as a potential treatment for patients with severe COVID-19 acute respiratory distress syndrome.
Product Name : AEVI-002
Product Type : Antibody
Upfront Cash : Inapplicable
August 13, 2020
Lead Product(s) : CERC-002
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AEVI-002
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cerecor Announces FDA Clearance of IND for CERC-002 in COVID-19 Induced ARDS
Details : U.S. Food and Drug Administration has given clearance to proceed with a proof-of-concept clinical trial of Cerecor's anti-LIGHT monoclonal antibody CERC-002 in patients with COVID-19 cytokine storm induced Acute Respiratory Distress Syndrome (ARDS).
Product Name : CERC-002
Product Type : Antibody
Upfront Cash : Inapplicable
May 28, 2020
Lead Product(s) : AEVI-002
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CERC-006
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Calidi Biotherapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Cerecor Receives Orphan Drug Designation for CERC-006 in Lymphatic Malformations
Details : U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation (ODD) to CERC-006, a dual inhibitor of mTOR complexes 1 and 2 for the treatment of lymphatic malformations (LM).
Product Name : CERC-006
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 08, 2020
Lead Product(s) : CERC-006
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Calidi Biotherapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable