Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : CSX-1004
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CSX-1004 is a human IgG1 monoclonal antibody under phase 1 clinical studies, it is specific for fentanyl and fentanyl analogs and works by sequestering fentanyl molecules & effectively neutralizing them in the blood before they reach the brain.
Brand Name : CSX-1004
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 31, 2023
Lead Product(s) : CSX-1004
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CSX-1004
Therapeutic Area : Psychiatry/Psychology
Study Phase : IND Enabling
Sponsor : National Institute on Drug Abuse
Deal Size : $14.8 million
Deal Type : Funding
Details : The funding will support development of a subcutaneous formulation of its anti-fentanyl monoclonal antibody, CSX-1004 SQ, an investigational product that has successfully entered Phase 1 studies for the reversal of acute opioid over dose of fentanyl and ...
Brand Name : CSX-1004
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 18, 2023
Lead Product(s) : CSX-1004
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : IND Enabling
Sponsor : National Institute on Drug Abuse
Deal Size : $14.8 million
Deal Type : Funding
Lead Product(s) : CSX-1004
Therapeutic Area : Psychiatry/Psychology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CSX-1004 is a recombinant human immunoglobulin G (IgG)1λ monoclonal antibody specific for fentanyl and related synthetic opioids. CSX-1004 is the first antibody-based therapy against fentanyl to gain IND approval.
Brand Name : CSX-1004
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 27, 2023
Lead Product(s) : CSX-1004
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CSX-1004
Therapeutic Area : Psychiatry/Psychology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CSX-1004 is a human antibody that binds to fentanyl and related synthetic opioids tightly and with high-specificity. It has been demonstrated to provide multi-week protection from fentanyl overdose during animal studies.
Brand Name : CSX-1004
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 28, 2023
Lead Product(s) : CSX-1004
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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