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Find Clinical Drug Pipeline Developments & Deals by Chrysalis BioTherapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The collaboration aims for evaluating Chrysalin (rusalatide acetate), a regenerative peptide drug, for the treatment of Cutaneous Radiation Injury (CRI).

                          Brand Name : Chrysalin

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          November 18, 2024

                          Lead Product(s) : Rusalatide Acetate

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : IND Enabling

                          Sponsor : National Institute of Allergy and Infectious Diseases

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Chrysalin (rusalatide acetate) is a natural regenerative peptide that accelerates tissue repair and revascularization while modulating the inflammatory response, which is investigated for Acute Respiratory Distress Syndrome.

                          Brand Name : Chrysalin

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          September 26, 2023

                          Lead Product(s) : Rusalatide Acetate

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Chrysalis will conduct safety studies and additional options required to achieve Emergency Use Authorization and Animal Rule approval for TP508 as a medicinal treatment for acute and delayed effects of ionizing radiation exposure.

                          Brand Name : TP508

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          December 01, 2020

                          Lead Product(s) : Rusalatide Acetate

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Undisclosed

                          Sponsor : BARDA

                          Deal Size : $10.4 million

                          Deal Type : Funding

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Funding from the NIAID COVID-19 contract is being used to complete in vivo testing of TP508 efficacy, drug product manufacture, and regulatory steps to initiate clinical trials in COVID-19 patients.

                          Brand Name : TP508

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          August 11, 2020

                          Lead Product(s) : Rusalatide Acetate

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : National Institutes of Health

                          Deal Size : $1.5 million

                          Deal Type : Funding

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : This award will allow Chrysalis BioTherapeutics to evaluate TP508 as a potential solution to prevent thrombosis and systemic vascular damage caused by SARS-CoV-2 infection.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          June 10, 2020

                          Lead Product(s) : Rusalatide Acetate

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : National Institute of Health

                          Deal Size : $0.9 million

                          Deal Type : Funding

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