Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Rusalatide Acetate
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Chrysalis Receives FDA Approval to Initiate Clinical Trials with Chrysalin™ (TP508)
Details : Chrysalin (rusalatide acetate) is a natural regenerative peptide that accelerates tissue repair and revascularization while modulating the inflammatory response, which is investigated for Acute Respiratory Distress Syndrome.
Brand Name : Chrysalin
Molecule Type : Peptide
Upfront Cash : Not Applicable
September 26, 2023
Lead Product(s) : Rusalatide Acetate
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Rusalatide Acetate
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Undisclosed
Sponsor : BARDA
Deal Size : $10.4 million
Deal Type : Funding
Details : Chrysalis will conduct safety studies and additional options required to achieve Emergency Use Authorization and Animal Rule approval for TP508 as a medicinal treatment for acute and delayed effects of ionizing radiation exposure.
Brand Name : TP508
Molecule Type : Peptide
Upfront Cash : Undisclosed
December 01, 2020
Lead Product(s) : Rusalatide Acetate
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Undisclosed
Sponsor : BARDA
Deal Size : $10.4 million
Deal Type : Funding
Lead Product(s) : Rusalatide Acetate
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : National Institutes of Health
Deal Size : $1.5 million
Deal Type : Funding
Details : Funding from the NIAID COVID-19 contract is being used to complete in vivo testing of TP508 efficacy, drug product manufacture, and regulatory steps to initiate clinical trials in COVID-19 patients.
Brand Name : TP508
Molecule Type : Peptide
Upfront Cash : Undisclosed
August 11, 2020
Lead Product(s) : Rusalatide Acetate
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : National Institutes of Health
Deal Size : $1.5 million
Deal Type : Funding
Lead Product(s) : Rusalatide Acetate
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : National Institute of Health
Deal Size : $0.9 million
Deal Type : Funding
Details : This award will allow Chrysalis BioTherapeutics to evaluate TP508 as a potential solution to prevent thrombosis and systemic vascular damage caused by SARS-CoV-2 infection.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 10, 2020
Lead Product(s) : Rusalatide Acetate
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : National Institute of Health
Deal Size : $0.9 million
Deal Type : Funding
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