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Capital Management"},{"orgOrder":0,"company":"Cidara Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"CD388","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Cidara Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Cidara Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Cidara Therapeutics \/ Not Applicable"}]

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                          01

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                          Details : CD388 is an investigational drug-Fc conjugate (DFC) comprised of multiple copies of a potent small molecule neuraminidase inhibitor, which is being evaluated for treating seasonal influenza.

                          Brand Name : CD388

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 23, 2024

                          Lead Product(s) : CD388

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          PackExpo
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                          Details : Through the divestment, Mundipharma received the rights for Rezzayo (rezafungin acetate), an echinocandin antifungal, approved for the treatment of invasive candidiasis in adults.

                          Brand Name : Rezzayo

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          April 24, 2024

                          Lead Product(s) : Rezafungin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Mundipharma

                          Deal Size : Undisclosed

                          Deal Type : Divestment

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                          03

                          PackExpo
                          Not Confirmed
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                          Details : Cidara has regained exclusive global development and commercial rights for CD388, which is under development for preventing all strains of influenza A and B.

                          Brand Name : CD388

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          April 24, 2024

                          Lead Product(s) : CD388

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Recipient : Johnson & Johnson

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          04

                          PackExpo
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                          PackExpo
                          Not Confirmed

                          Details : The net gross proceeds will be utilized to finance the clinical advancement of CD388, currently undergoing mid-stage clinical trials with patients for treating influenza.

                          Brand Name : CD388

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          April 24, 2024

                          Lead Product(s) : CD388

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : RA Capital Management

                          Deal Size : $240.0 million

                          Deal Type : Private Placement

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                          05

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : The payment triggered under the agreement is following the European approval of Rezzayo (rezafungin acetate), a novel, once-weekly echinocandin antifungal approved for invasive candidiasis in adults.

                          Brand Name : Rezzayo

                          Molecule Type : Peptide

                          Upfront Cash : $39.0 million

                          February 12, 2024

                          Lead Product(s) : Rezafungin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Mundipharma

                          Deal Size : $568.0 million

                          Deal Type : Partnership

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                          06

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Rezzayo (rezafungin acetate) is a novel once-weekly echinocandin antifungal approved by USFDA. It is now approved by MHRA for the treatment of invasive candidiasis in adults.

                          Brand Name : Rezzayo

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          January 29, 2024

                          Lead Product(s) : Rezafungin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Rezzayo (rezafungin) is an echinocandin antifungal that helps to inhibit the synthesis of 1,3-beta-D-glucan, an essential component of fungal cell walls. It recently got EU approval for the treatment of invasive candidiasis in adults.

                          Brand Name : Rezzayo

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 22, 2023

                          Lead Product(s) : Rezafungin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Rezzayo (rezafungin acetate) is a novel once-weekly echinocandin and 1,3-beta-glucan synthase inhibitor. It is approved for the treatment for Invasive Candidiasis in adults.

                          Brand Name : Rezzayo

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 06, 2023

                          Lead Product(s) : Rezafungin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Rezafungin is a novel once-weekly echinocandin being developed for both the treatment and prevention of serious fungal infections, such as invasive candidiasis and candidemia.

                          Brand Name : Rezzayo

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 13, 2023

                          Lead Product(s) : Rezafungin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Recipient : Mundipharma

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Under the agreement, Cidara is studying CD388, a second generation, anti-viral Fc conjugate (AVC), in Phase 1 and 2a clinical trials evaluating safety and pharmacokinetics as well as efficacy as pre-exposure prophylaxis against an influenza virus.

                          Brand Name : CD388

                          Molecule Type : Small molecule

                          Upfront Cash : $27.0 million

                          September 06, 2023

                          Lead Product(s) : CD388

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Johnson & Johnson Innovative Medicine

                          Deal Size : $780.0 million

                          Deal Type : Licensing Agreement

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