Lead Product(s) : Ciforadenant,Ipilimumab,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CPI-444 (ciforadenant) is an investigational small molecule, oral, checkpoint inhibitor designed to disable a tumor’s ability to subvert attack by the immune system by blocking the binding of adenosine in the tumor microenvironment to the A2A receptor.
Brand Name : CPI-444
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 25, 2022
Lead Product(s) : Ciforadenant,Ipilimumab,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ciforadenant,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Angel Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Corvus Pharmaceuticals Announces Co-Founding of Angel Pharmaceuticals in China
Details : Angel adds Corvus’ three clinical-stage candidates – ciforadenant, CPI-006 and CPI-818 and Corvus’ BTK inhibitor preclinical programs to its pipeline. Strategic collaboration gives Corvus 49.7% equity stake in Angel Pharmaceuticals.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 05, 2020
Lead Product(s) : Ciforadenant,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Angel Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Ciforadenant,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Data is based on results from the Company’s Phase 1b/2 trial of ciforadenant in patients with advanced RCC and demonstrates the potential role of CD68+ myeloid cells, which are a downstream target of adenosine as a biomarker to further enrich for respo...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 13, 2020
Lead Product(s) : Ciforadenant,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ciforadenant,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Corvus Pharmaceuticals Provides Business Update and Reports First Quarter 2020 Financial Results
Details : Corvus recemtly completed enrollment 25 patients with advanced refractory renal cell cancer in an amended ph 1b/2 clinical trial evaluating ciforadenant in combination with Genentech’s Tecentriq®.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 30, 2020
Lead Product(s) : Ciforadenant,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ciforadenant
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The mCRPC arm of the study, is evaluating ciforadenant monotherapy and in combination with Genentech’s Tecentriq® (atezolizumab), an anti-PD-L1 antibody.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 13, 2020
Lead Product(s) : Ciforadenant
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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