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Find Clinical Drug Pipeline Developments & Deals for Ciforadenant

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                          01

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : CPI-444 (ciforadenant) is a small molecule, oral, adenosine A2A receptor antagonist, designed to overcome resistance to anti-PD1 immunotherapy in metastatic castration resistant prostate cancer.

                          Product Name : CPI-444

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 11, 2024

                          Lead Product(s) : Ciforadenant,Atezolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : CPI-444 (ciforadenant) is an investigational small molecule, oral, checkpoint inhibitor designed to disable a tumor’s ability to subvert attack by the immune system by blocking the binding of adenosine in the tumor microenvironment to the A2A receptor.

                          Product Name : CPI-444

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 25, 2022

                          Lead Product(s) : Ciforadenant,Ipilimumab,Nivolumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Data is based on results from the Company’s Phase 1b/2 trial of ciforadenant in patients with advanced RCC and demonstrates the potential role of CD68+ myeloid cells, which are a downstream target of adenosine as a biomarker to further enrich for respo...

                          Product Name : CPI-444

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 13, 2020

                          Lead Product(s) : Ciforadenant,Atezolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Angel adds Corvus’ three clinical-stage candidates – ciforadenant, CPI-006 and CPI-818 and Corvus’ BTK inhibitor preclinical programs to its pipeline. Strategic collaboration gives Corvus 49.7% equity stake in Angel Pharmaceuticals.

                          Product Name : CPI-444

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          May 10, 2020

                          Lead Product(s) : Ciforadenant,Atezolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Angel Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Corvus recemtly completed enrollment 25 patients with advanced refractory renal cell cancer in an amended ph 1b/2 clinical trial evaluating ciforadenant in combination with Genentech’s Tecentriq®.

                          Product Name : CPI-444

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 30, 2020

                          Lead Product(s) : Ciforadenant,Atezolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : The mCRPC arm of the study, is evaluating ciforadenant monotherapy and in combination with Genentech’s Tecentriq® (atezolizumab), an anti-PD-L1 antibody.

                          Product Name : CPI-444

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 13, 2020

                          Lead Product(s) : Ciforadenant

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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