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Placement","leadProduct":"Cadonilimab","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Akeso","amount2":0.25,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Akeso \/ Undisclosed","highestDevelopmentStatusID":"12","companyTruncated":"Akeso \/ Undisclosed"},{"orgOrder":0,"company":"Shanghai Junshi Biosciences","sponsor":"TopAlliance Biosciences","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Toripalimab","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Shanghai Junshi Biosciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Shanghai Junshi Biosciences \/ TopAlliance Biosciences","highestDevelopmentStatusID":"12","companyTruncated":"Shanghai Junshi Biosciences \/ TopAlliance Biosciences"},{"orgOrder":0,"company":"BeiGene","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Tislelizumab","moa":"","graph1":"Technology","graph2":"Approved","graph3":"BeiGene","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"BeiGene \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"BeiGene \/ Not Applicable"},{"orgOrder":0,"company":"Genelux","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Cisplatin","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Genelux","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Genelux \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Genelux \/ Not Applicable"},{"orgOrder":0,"company":"Akeso","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Cisplatin","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Akeso","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Akeso \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Akeso \/ Not Applicable"},{"orgOrder":0,"company":"Shanghai Junshi Biosciences","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Toripalimab","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Shanghai Junshi Biosciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Shanghai Junshi Biosciences \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Shanghai Junshi Biosciences \/ Not Applicable"},{"orgOrder":0,"company":"BeiGene","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Tislelizumab","moa":"","graph1":"Technology","graph2":"Approved","graph3":"BeiGene","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"BeiGene \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"BeiGene \/ Not Applicable"},{"orgOrder":0,"company":"Dr. Reddy's Laboratories","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Toripalimab","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Dr. Reddy\\'s Laboratories","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Dr. Reddy\\'s Laboratories \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Dr. Reddy\\'s Laboratories \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals for Cisplatin

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Toripalimab,Cisplatin,Gemcitabine

                          Therapeutic Area : Oncology

                          Study Phase : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Zytorvi (toripalimab) is an approved anti-PD-1 monoclonal antibody, in combination with cisplatin and gemcitabine for the first-line treatment of adults with metastatic nasopharyngeal carcinoma.

                          Brand Name : Zytorvi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 28, 2024

                          Lead Product(s) : Toripalimab,Cisplatin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Dr Reddy Company Banner

                          02

                          Lead Product(s) : Toripalimab,Cisplatin,Gemcitabine

                          Therapeutic Area : Oncology

                          Study Phase : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Loqtorzi (toripalimab-tpzi) is an anti-PD-1 monoclonal antibody approved in combination with cisplatin and gemcitabine for first-line treatment of metastatic or recurrent nasopharyngeal carcinoma.

                          Brand Name : Loqtorzi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 18, 2024

                          Lead Product(s) : Toripalimab,Cisplatin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Dr Reddy Company Banner

                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Tevimbra (tislelizumab) is a uniquely designed humanized IgG4 PD-1 mAb, being evaluated for the treatment of first-line gastric or gastroesophageal junction cancers.

                          Brand Name : Tevimbra

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 27, 2024

                          Lead Product(s) : Tislelizumab,Oxaliplatin,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Loqtorzi (toripalimab) is an approved anti-PD-1 monoclonal antibody, in combination with cisplatin and gemcitabine for the first-line treatment of adults with metastatic nasopharyngeal carcinoma.

                          Brand Name : Loqtorzi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 16, 2024

                          Lead Product(s) : Toripalimab,Cisplatin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : AK112 (ivonescimab) a PD-1/VEGF bispecific antibody is being developed in combination with gemcitabine & cisplatin as the first-line treatment of advanced biliary tract cancers.

                          Brand Name : AK112

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 31, 2024

                          Lead Product(s) : Ivonescimab,Gemcitabine,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Olvi-Vec is a proprietary, modified oncolytic vaccinia virus, a stable DNA virus with a large engineering capacity. Genelux is developing Olvi-Vec in patients with advanced or metastatic NSCLC.

                          Brand Name : Olvi-Vec

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 22, 2024

                          Lead Product(s) : Olvimulogene Nanivacirepvec,Cisplatin,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Tevimbra (tislelizumab) is a uniquely designed humanized IgG4 PD-1 mAb, being evaluated for the treatment of first-line gastric or gastroesophageal junction cancers.

                          Brand Name : Tevimbra

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 21, 2024

                          Lead Product(s) : Tislelizumab,Oxaliplatin,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Loqtorzi (toripalimab) is an approved anti-PD-1 monoclonal antibody, in combination with cisplatin and gemcitabine for the first-line treatment of adults with metastatic nasopharyngeal carcinoma.

                          Brand Name : Loqtorzi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 15, 2024

                          Lead Product(s) : Toripalimab,Cisplatin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : TopAlliance Biosciences

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The proceeds will be used in accelerating the global clinical development of innovative drugs developed internally by Akeso, including AK-104 (cadonilimab) for first-line treatment of cervical cancer.

                          Brand Name : AK104

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          October 13, 2024

                          Lead Product(s) : Cadonilimab,Cisplatin,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : $250.0 million

                          Deal Type : Private Placement

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                          10

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : LBL-024 is a bispecific antibody, binds to PD-L1 with high affinity, blocking the PD-L1/PD-1 pathway while activating the 4-1BB pathway in the tumor microenvironment.

                          Brand Name : LBL-024

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 10, 2024

                          Lead Product(s) : LBL-024,Etoposide,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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