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Wainwright & Co"},{"orgOrder":0,"company":"Citius Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Minocycline Hydrochloride","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Citius Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Citius Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Citius Pharmaceuticals \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals by Citius Pharmaceuticals

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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Mino-Lok (MLT) is a novel antibiotic lock therapy that combines minocycline with edetate disodium, which is investigated for the treatment of patients with catheter-related blood stream infections.

                          Brand Name : Mino-Lok

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 25, 2024

                          Lead Product(s) : Minocycline Hydrochloride,Edetate Calcium Disodium,Ethanol

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The Company will use the proceeds for pre-clinical and clinical development of its product candidates, including Lymphir (denileukin diftitox) in combination of Keytruda for recurrent solid tumors.

                          Brand Name : Lymphir

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          November 18, 2024

                          Lead Product(s) : Denileukin Diftitox,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : H.C. Wainwright & Co

                          Deal Size : $3.0 million

                          Deal Type : Public Offering

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The Company will use the proceeds for pre-clinical and clinical development of its product candidates, including Lymphir (denileukin diftitox) in combination of Keytruda for recurrent solid tumors.

                          Brand Name : Lymphir

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          November 15, 2024

                          Lead Product(s) : Denileukin Diftitox,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : H.C. Wainwright & Co

                          Deal Size : $3.0 million

                          Deal Type : Private Placement

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Keytruda (pembrolizumab) and Lymphir (denileukin diftitox-cxdl or E7777, an IL-2R binder) is being investigated in patients with recurrent solid tumors.

                          Brand Name : Lymphir

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 11, 2024

                          Lead Product(s) : Denileukin Diftitox,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Lymphir (denileukin diftitox) is a recombinant fusion protein that combines the IL-2R binding domain with diphtheria toxin fragments, approved for adults with R/R cutaneous T-cell lymphoma.

                          Brand Name : Lymphir

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 09, 2024

                          Lead Product(s) : Denileukin Diftitox

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Mino-Lok (MLT) is a novel antibiotic lock therapy that combines minocycline with edetate disodium, which is investigated for the treatment of patients with catheter-related blood stream infections.

                          Brand Name : Mino-Lok

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 21, 2024

                          Lead Product(s) : Minocycline Hydrochloride,Edetate Calcium Disodium,Ethanol

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Citius intends to use proceeds for the pre-clinical and clinical development of Lymphir (denileukin diftitox), a recombinant fusion protein combining interleukin-2 and diphtheria toxin.

                          Brand Name : Lymphir

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          April 26, 2024

                          Lead Product(s) : Denileukin Diftitox,Tisagenlecleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : H.C. Wainwright & Co

                          Deal Size : $15.0 million

                          Deal Type : Private Placement

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                          08

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Lymphir™ (denileukin diftitox) in combination with FDA-approved CAR-T products like tisagenlecleucel or lisocabtagene maraleucel is being investigated for relapsed or refractory B-cell lymphomas.

                          Brand Name : Lymphir

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 11, 2024

                          Lead Product(s) : Denileukin Diftitox,Tisagenlecleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Lymphir (denileukin diftitox) is a recombinant fusion protein combining the IL-2 receptor binding domain with diphtheria toxin, being evaluated for relapsed or refractory cutaneous T-cell lymphoma.

                          Brand Name : Lymphir

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 18, 2024

                          Lead Product(s) : Denileukin Diftitox

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Lead Product(s) : Denileukin Diftitox

                          Therapeutic Area : Oncology

                          Study Phase : Approved

                          Sponsor : New Jersey Economic Development Authority

                          Deal Size : $2.4 million

                          Deal Type : Funding

                          Details : Net proceeds will be used for the development of Lymphir, a purified reformulation of denileukin diftitox, for treating PTCL and immuno-oncology indications.

                          Brand Name : Lymphir

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          March 07, 2024

                          Lead Product(s) : Denileukin Diftitox

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : New Jersey Economic Development Authority

                          Deal Size : $2.4 million

                          Deal Type : Funding

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