Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Vonoprazan Fumarate,Amoxicillin Trihydrate,Clarithromycin
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Phathom Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
Evonik and Phathom Pharmaceuticals Partner to Produce Novel Acid-Blocker Vonoprazan
Details : Vonoprazan is a novel potassium-competitive acid blocker (PCAB). It inhibits gastric acid secretion by acting as a reversible competitive inhibitor against potassium ions.
Brand Name : Voquezna Triple Pack
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 24, 2022
Lead Product(s) : Vonoprazan Fumarate,Amoxicillin Trihydrate,Clarithromycin
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Phathom Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Vonoprazan Fumarate,Amoxicillin Trihydrate,Clarithromycin
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VOQUEZNA® TRIPLE PAK® (vonoprazan, amoxicillin, clarithromycin) contain vonoprazan, an oral small molecule potassium-competitive acid blocker (PCAB) co-packaged with antibiotics. It has been approved by FDA for the treatment of H. pylori infection in a...
Brand Name : Voquezna Triple Pak
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 30, 2023
Lead Product(s) : Vonoprazan Fumarate,Amoxicillin Trihydrate,Clarithromycin
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RHB-204 (clarithromycin) is a 70s Bacterial ribosome inhibitor combination of clarithromycin, rifabutin, and clofazimine, developed for the treatment of pulmonary NTM disease caused by Mycobacterium avium Complex (MAC).
Brand Name : RHB-204
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 22, 2023
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : H.C. Wainwright & Co.
Deal Size : $6.0 million
Deal Type : Public Offering
RedHill Biopharma Announces Closing of $6 Million Registered Direct Offering
Details : The Company intends to use the net proceeds for the development of RHB-204, a proprietary, fixed-dose oral capsule containing a combination of clarithromycin, rifabutin, and clofazimine, developed for the treatment of pulmonary NTM disease caused by MAC.
Brand Name : RHB-204
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 03, 2023
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : H.C. Wainwright & Co.
Deal Size : $6.0 million
Deal Type : Public Offering
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : H.C. Wainwright & Co.
Deal Size : $6.0 million
Deal Type : Public Offering
RedHill Biopharma Announces $6 Million Registered Direct Offering
Details : The net proceeds will be used in the development of RHB-204, a proprietary, fixed-dose oral capsule containing a combination of clarithromycin, rifabutin, and clofazimine, developed for the treatment of pulmonary NTM disease caused by Mycobacterium avium...
Brand Name : RHB-204
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 30, 2023
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : H.C. Wainwright & Co.
Deal Size : $6.0 million
Deal Type : Public Offering
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : $6.0 million
Deal Type : Private Placement
Details : RHB-204 (clarithromycin) is a proprietary, fixed-dose oral capsule containing a combination of clarithromycin, rifabutin, and clofazimine, developed for the treatment of pulmonary NTM disease caused by Mycobacterium avium Complex (MAC).
Brand Name : RHB-204
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 08, 2023
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : $6.0 million
Deal Type : Private Placement
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RHB-204 is a Phase 3-stage proprietary, xed-dose oral capsule containing a combination of clarithromycin, rifabutin and clofazimine, developed for the treatment of pulmonary NTM disease caused by MAC.
Brand Name : RHB-204
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 26, 2023
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
RedHill Biopharma Announces EU Orphan Drug Designation for RHB-204 for NTM Infections
Details : RHB-204 is a proprietary, fixed-dose oral capsule containing a combination of clarithromycin, rifabutin and clofazimine, developed for the treatment of pulmonary NTM infections caused by Mycobacterium avium Complex (MAC).
Brand Name : RHB-204
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 17, 2022
Lead Product(s) : Clarithromycin,Rifabutin,Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vonoprazan Fumarate,Amoxicillin Trihydrate,Clarithromycin
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Phathom Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Catalent Supports U.S. Launch of Phathom Pharmaceuticals’ New Products Following Regulatory Approval
Details : Voquezna (vonoprazan) new treatment options contain antibiotics conveniently packaged with vonoprazan, a novel potassium-competitive acid blocker (PCAB) and the first innovative acid suppressant from a new drug class approved in the U.S. in over 30 years...
Brand Name : Voquezna
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 09, 2022
Lead Product(s) : Vonoprazan Fumarate,Amoxicillin Trihydrate,Clarithromycin
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Phathom Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vonoprazan Fumarate,Amoxicillin Trihydrate,Clarithromycin
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VOQUEZNA TRIPLE PAK (vonoprazan, amoxicillin, clarithromycin) is an orally administered potassium-competitive acid blocker from a new class of acid suppressant agents and under development for treatment of erosive esophagitis and non-erosive gastroesopha...
Brand Name : Voquezna Triple Pack
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 24, 2022
Lead Product(s) : Vonoprazan Fumarate,Amoxicillin Trihydrate,Clarithromycin
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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