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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : The proceeds will be used to file a new drug application under the accelerated approval pathway for CNM-Au8, a catalytically active gold nanocrystal suspension.

                          Brand Name : CNM-Au8

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 01, 2024

                          Lead Product(s) : CNM-Au8

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : SymBiosis

                          Deal Size : $7.3 million

                          Deal Type : Public Offering

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                          02

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : CNM-Au8 is a catalytically-active gold nanocrystal neuroprotective agent that enhances intracellular energy metabolism, in development for amyotrophic lateral sclerosis.

                          Brand Name : CNM-Au8

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 16, 2024

                          Lead Product(s) : CNM-Au8

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : CNM-Au8 is a catalytically-active gold nanocrystal neuroprotective agent that enhances intracellular energy metabolism, in development for amyotrophic lateral sclerosis.

                          Brand Name : CNM-Au8

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 06, 2024

                          Lead Product(s) : CNM-Au8

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : CNM-Au8 is a catalytically-active gold nanocrystal neuroprotective agent that enhances intracellular energy metabolism, in development for amyotrophic lateral sclerosis.

                          Brand Name : CNM-Au8

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 28, 2024

                          Lead Product(s) : CNM-Au8

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : NIH

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : CNM-Au8 is a catalytically-active gold nanocrystal neuroprotective agent that enhances intracellular energy metabolism. It is in development for treating amyotrophic lateral sclerosis.

                          Brand Name : CNM-Au8

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          February 22, 2024

                          Lead Product(s) : CNM-Au8

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : CNM-Au8, an oral gold nanocrystal suspension, is designed to restore neuronal health by enhancing neuroprotection, remyelination, and neuronal resilience against disease-relevant stressors.

                          Brand Name : CNM-Au8

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 08, 2024

                          Lead Product(s) : CNM-Au8

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : CNM-Au8 is a ROS inhibitor small molecule drug candidate, which is currently being evaluated for the treatment of patients with amyotrophic lateral sclerosis.

                          Brand Name : CNM-Au8

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 21, 2023

                          Lead Product(s) : CNM-Au8

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : The funding will support an Expanded Access Protocol for the Company’s investigational drug, CNM-Au8, an investigational first-in-class therapy, in amyotrophic lateral sclerosis (ALS).

                          Brand Name : CNM-Au8

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 05, 2023

                          Lead Product(s) : CNM-Au8

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : National Institute of Neurological Disorders and Stroke

                          Deal Size : $45.1 million

                          Deal Type : Funding

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                          09

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : CNM-Au8 is an oral suspension of gold nanocrystals developed to restore neuronal health and function by increasing energy producing reactions that enable neuroprotection and remyelination by increasing neuronal and glial resilience to disease-relevant st...

                          Brand Name : CNM-Au8

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 25, 2023

                          Lead Product(s) : CNM-Au8

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : CNM-Au8 is an oral suspension of gold nanocrystals developed to restore neuronal health and function by increasing energy producing reactions that enable neuroprotection and remyelination by increasing neuronal and glial resilience to disease-relevant st...

                          Brand Name : CNM-Au8

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 29, 2023

                          Lead Product(s) : CNM-Au8

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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