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    [{"orgOrder":0,"company":"Clinigen Group","sponsor":"Iovance Biotherapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Large molecule","year":"2020","type":"Agreement","leadProduct":"Aldesleukin","moa":"Il-2 receptor","graph1":"Oncology","graph2":"Approved","graph3":"Clinigen Group","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Clinigen Group \/ Iovance Biotherapeutics","highestDevelopmentStatusID":"12","companyTruncated":"Clinigen Group \/ Iovance Biotherapeutics"},{"orgOrder":0,"company":"Clinigen Group","sponsor":"Porton Biopharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Large molecule","year":"2020","type":"Licensing Agreement","leadProduct":"Asparaginase","moa":"","graph1":"Oncology","graph2":"Approved","graph3":"Clinigen 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Therapeutics","highestDevelopmentStatusID":"12","companyTruncated":"Clinigen Group \/ CNX Therapeutics"},{"orgOrder":0,"company":"Clinigen Group","sponsor":"Santhera Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"SWITZERLAND","productType":"Steroid","year":"2025","type":"Agreement","leadProduct":"Vamorolone","moa":"Glucocorticoid receptor","graph1":"Genetic Disease","graph2":"Approved FDF","graph3":"Clinigen Group","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Clinigen Group \/ Clinigen Group","highestDevelopmentStatusID":"15","companyTruncated":"Clinigen Group \/ Clinigen Group"}]

    Find Clinical Drug Pipeline Developments & Deals by Clinigen Group

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                            01

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                            Lead Product(s) : Vamorolone

                            Therapeutic Area : Genetic Disease

                            Study Phase : Approved FDF

                            Recipient : Santhera Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Santhera, Clinigen Sign Supply, Distribution Deal for AGAMREE® (Vamorolone)

                            Details : Under the agreement, Clinigen Group will supply and distribute Agamree (vamorolone) in countries where the product is not otherwise commercially available.

                            Product Name : Agamree

                            Product Type : Steroid

                            Upfront Cash : Undisclosed

                            January 06, 2025

                            Lead Product(s) : Vamorolone

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Approved FDF

                            Recipient : Santhera Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            02

                            Clinigen Group

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                            Lead Product(s) : Dexrazoxane

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : CNX Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Clinigen Divests Global Rights to Four Cancer Support Therapies to CNX Therapeutics

                            Details : Under the terms of the divestment, Clinigen will divest four medicines, Cardioxane (dexrazoxane), Savene, Totect and Ethyol, all of which help mitigate the side effects patients may experience when treated with other cancer therapies, to CNX Therapeutics...

                            Product Name : Cardioxane

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            August 10, 2023

                            Lead Product(s) : Dexrazoxane

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : CNX Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Divestment

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                            03

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                            Lead Product(s) : Aldesleukin

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Iovance Biotherapeutics

                            Deal Size : $206.3 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Clinigen Divests Proleukin® to Iovance Biotherapeutics for £166.7 million

                            Details : Proleukin® (aldesleukin), a form of interleukin-2, is indicated for the treatment of adults with metastatic melanoma (mM) and metastatic renal cell carcinoma (mRCC).

                            Product Name : Proleukin

                            Product Type : Large molecule

                            Upfront Cash : $206.3 million

                            January 23, 2023

                            Lead Product(s) : Aldesleukin

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Iovance Biotherapeutics

                            Deal Size : $206.3 million

                            Deal Type : Divestment

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                            04

                            Clinigen Group

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                            Lead Product(s) : Relugolix

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clinigen Initiates A Managed Access Program For Relugolix In Europe For The Treatment Of Advanced Hormone-sens...

                            Details : Orgovyx (relugolix), was granted approval by the European Medicines Agency (EMA) in April 2022 for the treatment of adult patients with advanced hormone-sensitive prostate cancer.

                            Product Name : Orgovyx

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 20, 2022

                            Lead Product(s) : Relugolix

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Clinigen Group

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                            Lead Product(s) : Aldesleukin,Riluzole

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clinigen Notes Results from The MIROCALS Trial Investigating Low Dose Proleukin® (aldesleukin) In Patients wi...

                            Details : Clinigen confirms that Proleukin, interleukin-2 (aldesleukin), supplied for the MIROCALS trial, is currently licensed for metastatic renal cell carcinoma and melanoma in the US and metastatic renal cell carcinoma in certain other countries.

                            Product Name : Proleukin

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            December 08, 2022

                            Lead Product(s) : Aldesleukin,Riluzole

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

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                            Lead Product(s) : Lenzilumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Recipient : Humanigen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Humanigen Launches Managed Access Program for Lenzilumab

                            Details : Humaneered (lenzilumab), is an investigational product that is not currently authorized or approved in any country, now available for certain hospitalized COVID-19 patients through its newly-launched LenzMAP.

                            Product Name : Humaneered

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            February 09, 2022

                            Lead Product(s) : Lenzilumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Recipient : Humanigen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Clinigen Group

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                            Lead Product(s) : Dexrazoxane

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clinigen’s Totect® Receives FDA Approval for New Indication to Treat Incidence and Severity of Cardiomyopat...

                            Details : Totect® now can be used for reducing the incidence and severity of cardiomyopathy associated with doxorubicin in women with breast cancer who have received a cumulative doxorubicin dose of 300 mg/m² and who will continue to receive doxorubicin therapy.

                            Product Name : Totect

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 10, 2020

                            Lead Product(s) : Dexrazoxane

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Clinigen Group

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                            Clinigen Group

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                            Lead Product(s) : Interferon Beta-1A

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Synairgen

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Synairgen and Clinigen Sign Managed Access Program Agreement with SNG001 for Treatment of Hospitalised Patient...

                            Details : The collaboration will be working to progress SNG001 through the required clinical and regulatory channels to make this potentially critical treatment widely available to COVID-19 patients around the world.

                            Product Name : SNG001

                            Product Type : Large molecule

                            Upfront Cash : Undisclosed

                            September 29, 2020

                            Lead Product(s) : Interferon Beta-1A

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Synairgen

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            09

                            Clinigen Group

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                            Lead Product(s) : Aldesleukin

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clinigen's ALS Therapy Bags US Orphan Status

                            Details : According to the firm, the ODD recognises the potential therapeutic role of aldesleukin in treating disease, and could provide a number of benefits for Clinigen should it obtain a marketing approval for this indication.

                            Product Name : Proleukin

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 13, 2020

                            Lead Product(s) : Aldesleukin

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Clinigen Group

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                            Lead Product(s) : Interleukin 2,Tumor infiltrating lymphocyte,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clinigen Demonstrates IL-2 Plays Role in Emerging TIL Therapies

                            Details : Study aimed at evaluating the safety and efficacy of TIL therapy in metastatic NSCLC (mNSCLC) after evidence of progression on nivolumab.

                            Product Name : Undisclosed

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            May 04, 2020

                            Lead Product(s) : Interleukin 2,Tumor infiltrating lymphocyte,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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