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    [{"orgOrder":0,"company":"Clovis Oncology","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Rucaparib Camsylate","moa":"PARP 1\/2\/3","graph1":"Oncology","graph2":"Phase III","graph3":"Clovis Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Clovis Oncology \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Clovis Oncology \/ Not Applicable"},{"orgOrder":0,"company":"Clovis Oncology","sponsor":"J. P. 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molecule","year":"2022","type":"Not Applicable","leadProduct":"Rucaparib Camsylate","moa":"PARP1\/2\/3","graph1":"Oncology","graph2":"Approved","graph3":"Clovis Oncology","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Clovis Oncology \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Clovis Oncology \/ Not Applicable"},{"orgOrder":0,"company":"Clovis Oncology","sponsor":"Novartis Innovative Therapies","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Peptide","year":"2022","type":"Divestment","leadProduct":"177Lu-FAP-2286","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Clovis Oncology","amount2":0.68000000000000005,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.68000000000000005,"dosageForm":"Infusion","sponsorNew":"Clovis Oncology \/ Novartis Innovative Therapies","highestDevelopmentStatusID":"7","companyTruncated":"Clovis Oncology \/ Novartis Innovative Therapies"}]

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                            01

                            Clovis Oncology

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                            euroPLX 86 Munich
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                            Clovis Oncology

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                            Lead Product(s) : 177Lu-FAP-2286

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Novartis Innovative Therapies

                            Deal Size : $680.7 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Clovis Oncology Files for Chapter 11 Protection and Enters into Agreement to Sell FAP-2286

                            Details : 177Lu-FAP-2286 is a peptide-targeted radionuclide therapy (PTRT) and imaging agent targeting FAP. FAP-2286 consists of two functional elements; a targeting peptide that binds to FAP and a site that can be used to attach radioactive isotopes for imaging a...

                            Brand Name : 177Lu-FAP-2286

                            Molecule Type : Peptide

                            Upfront Cash : $50.0 million

                            December 12, 2022

                            Lead Product(s) : 177Lu-FAP-2286

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Novartis Innovative Therapies

                            Deal Size : $680.7 million

                            Deal Type : Divestment

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                            02

                            Clovis Oncology

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                            euroPLX 86 Munich
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                            Clovis Oncology

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                            euroPLX 86 Munich
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                            Lead Product(s) : Rucaparib Camsylate

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clovis Oncology Presents Data from TRITON3 Phase 3 Trial of Rubraca® (rucaparib) at the 29th Annual Prostate ...

                            Details : Rubraca(Rucaparib) is an oral, small molecule inhibitor of PARP1, PARP2 and PARP3 being developed in multiple tumor types, including ovarian and metastatic castration-resistant prostate cancers, as monotherapy, and in combination with other anti-cancer a...

                            Brand Name : Rubraca

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 27, 2022

                            Lead Product(s) : Rucaparib Camsylate

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Clovis Oncology

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                            Clovis Oncology

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                            Lead Product(s) : 177Lu-FAP-2286

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Isotopia

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Clovis Oncology and Isotopia Announce Lutetium-177 Clinical Supply Agreement

                            Details : 177Lu-FAP-2286 consists of two functional elements; a targeting peptide that binds to FAP and a site that can be used to attach medical radioisotopes, such as lutetium-177 for therapeutic use, or gallium-68 for imaging use.

                            Brand Name : 177Lu-FAP-2286

                            Molecule Type : Peptide

                            Upfront Cash : Undisclosed

                            September 21, 2022

                            Lead Product(s) : 177Lu-FAP-2286

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Isotopia

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            04

                            Clovis Oncology

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                            euroPLX 86 Munich
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                            Clovis Oncology

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                            euroPLX 86 Munich
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                            Lead Product(s) : Rucaparib Camsylate

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clovis Oncology Submits Applications for Rubraca® Label Expansion in the US and European Union as First-line ...

                            Details : The ATHENA-MONO trial met its primary endpoint, showing Rubraca (rucaparib) monotherapy versus placebo improved progression-free survival (PFS) by investigator assessment in both populations in the primary efficacy analyses: HRD-positive and all patients...

                            Brand Name : Rubraca

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 13, 2022

                            Lead Product(s) : Rucaparib Camsylate

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Clovis Oncology

                            U.S.A arrow
                            euroPLX 86 Munich
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                            Clovis Oncology

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                            euroPLX 86 Munich
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                            Lead Product(s) : Rucaparib Camsylate,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clovis Oncology’s Rubraca® (Rucaparib) as First-Line Maintenance Treatment Improves Progression-Free Surviv...

                            Details : Rubraca (rucaparib) is an oral, small molecule inhibitor of PARP1, PARP2 and PARP3 being developed in multiple tumor types, including ovarian and metastatic castration-resistant prostate cancers, as monotherapy, and in combination with other anti-cancer ...

                            Brand Name : Rubraca

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 11, 2022

                            Lead Product(s) : Rucaparib Camsylate,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Clovis Oncology

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                            euroPLX 86 Munich
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                            Clovis Oncology

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                            Lead Product(s) : 177Lu-FAP-2286

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clovis Oncology Highlights Phase 1 Data from Ongoing Clinical Studies of Targeted Radiotherapy Candidate FAP-2...

                            Details : Overall, in nine patients treated in the first two dose cohorts,177Lu-FAP-2286 demonstrated a manageable safety profile and encouraging evidence of activity, including a confirmed RECIST partial response in one patient.

                            Brand Name : 177Lu-FAP-2286

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            June 14, 2022

                            Lead Product(s) : 177Lu-FAP-2286

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Clovis Oncology

                            U.S.A arrow
                            euroPLX 86 Munich
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                            Clovis Oncology

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                            euroPLX 86 Munich
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                            Lead Product(s) : Rucaparib Camsylate,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clovis Oncology’s Rubraca® (Rucaparib) as First-Line Maintenance Treatment Significantly Improves Progressi...

                            Details : The ATHENA-MONO trial met its primary endpoint, showing Rubraca (rucaparib) monotherapy versus placebo improved progression-free survival (PFS) by investigator assessment in both populations in the primary efficacy analyses: HRD-positive and all patients...

                            Brand Name : Rubraca

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 06, 2022

                            Lead Product(s) : Rucaparib Camsylate,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Clovis Oncology

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                            Clovis Oncology

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                            Lead Product(s) : Rucaparib Camsylate,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Clovis Oncology Highlights Rubraca® (Rucaparib) and FAP-2286 Data to be Presented at 2022 ASCO Annual Meeting

                            Details : Rucaparib, an oral, small molecule inhibitor of poly (ADP-ribose) polymerase (PARP)1, 2 and 3 is being developed in multiple tumor types, including ovarian and prostate cancers, as monotherapy and in combination with other anti-cancer agents.

                            Brand Name : Rubraca

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 28, 2022

                            Lead Product(s) : Rucaparib Camsylate,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Clovis Oncology

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                            euroPLX 86 Munich
                            Not Confirmed

                            Clovis Oncology

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : 177Lu-FAP-2286

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : University of Heidelberg

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Clovis Oncology Highlights Presentations on FAP-2286 and Rubraca® (Rucaparib) at the AACR Annual Meeting 2022

                            Details : In non-clinical data analysis, FAP-2286 demonstrated potent activity for human fibroblast activation protein by biochemical and cell-based assays, 177Lu-FAP-2286 showed longer tumor retention, resulting in greater tumor inhibition as compared to 177LuFAP...

                            Brand Name : 177Lu-FAP-2286

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            April 08, 2022

                            Lead Product(s) : 177Lu-FAP-2286

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : University of Heidelberg

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Clovis Oncology

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                            euroPLX 86 Munich
                            Not Confirmed

                            Clovis Oncology

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Rucaparib Camsylate

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Clovis Oncology’s Rubraca® (Rucaparib) Significantly Improves Progression-Free Survival in First-line Maint...

                            Details : Rucaparib is an oral, small molecule inhibitor of PARP1, PARP2 and PARP3 being developed in multiple tumor types, including ovarian and metastatic castration-resistant prostate cancers, as monotherapy, and in combination with other anti-cancer agents.

                            Brand Name : Rubraca

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 31, 2022

                            Lead Product(s) : Rucaparib Camsylate

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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