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Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"CNBX Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"CNBX Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"CNBX Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"RCC-33","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"CNBX Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"CNBX Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"CNBX Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"CNBX Pharmaceuticals","sponsor":"Not 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Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"CNBX Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"CNBX Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"CNBX RCC-33","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"CNBX Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"CNBX Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"CNBX Pharmaceuticals \/ Not Applicable"}]

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : CNBX® RCC-33 is an novel cannabinoid-based formulation demonstrated with significant synergistic antitumor effect for the treatment of Colorectal Cancer.

                          Brand Name : CNBX RCC-33

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 18, 2022

                          Lead Product(s) : CNBX RCC-33

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : CNBX RCC-33, a novel cannabinoid-based formulation, is used for the treatment of colorectal cancer currently being developed and prepared for a pre-IND meeting with the FDA and a first-in-human Phase I/II(a) validation study.

                          Brand Name : CNBX RCC-33

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 13, 2022

                          Lead Product(s) : CNBX RCC-33

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : RCC-33, a novel cannabinoid-based formulation, demonstrated significant synergistic antitumor effect in pre clinical studies, for the treatment of colorectal cancer.

                          Brand Name : RCC-33

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 05, 2022

                          Lead Product(s) : RCC-33

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : Under the agreement, Purisys will support an IND filing process, including providing all necessary and related information concerning Chemistry Manufacturing and Controls (CMC) in the form of a comprehensive technical package to be presented to the FDA r...

                          Brand Name : RCC-33

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          November 04, 2021

                          Lead Product(s) : RCC-33

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Purisys LLC

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          05

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : Cannabics™ RCC-33 is the first proprietary antitumor formulation we have released for in-vivo testing for treating cancer, including colorectal cancer and early intervention therapy for colorectal cancer patients.

                          Brand Name : RCC-33

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 18, 2021

                          Lead Product(s) : RCC-33

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : The company is gearing up for submission of a pre-IND meeting package and meeting request to the US Food and Drug Administration regarding its Colorectal Cancer treatment drug candidate RCC-33.

                          Brand Name : RCC-33

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 03, 2021

                          Lead Product(s) : RCC-33

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : The launching of the new research program for the development of Melanoma treatment follows a previous development by the company of Cannabics® RCC-33, who demonstrated a 33% reduction in tumor volume and a 35% increase in survival rate in recent in-viv...

                          Brand Name : RCC-33

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 26, 2021

                          Lead Product(s) : RCC-33

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : The announcement comes after the company was able to obtain a license from the Israeli Ministry of Health to conduct scientific research using Psylocibin and Psilocin in the company's in-house laboratory facilities in Rehovot, Israel.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 20, 2021

                          Lead Product(s) : Psilocybine

                          Therapeutic Area : Oncology

                          Highest Development Status : Undisclosed

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : The Dose Response Study comes in light of previously reported results indicating a 33% reduction in tumor volume and a 35% prolonged survival rate in mice inoculated with human colorectal cancer cells and exposed to Cannabics™ RCC-33.

                          Brand Name : RCC-33

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 31, 2021

                          Lead Product(s) : RCC-33

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : The final study results demonstrate a significant and robust inhibitory effect on tumor growth, as evidenced by a 33% reduction in tumor volume in mice exposed to RCC-33 in comparison with sham control mice.

                          Brand Name : RCC-33

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          February 16, 2021

                          Lead Product(s) : RCC-33

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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