[{"orgOrder":0,"company":"Beverly Hills","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Dimethyl Sulfone","moa":"DHT","graph1":"Dermatology","graph2":"Approved","graph3":"Beverly Hills","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Beverly Hills \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Beverly Hills \/ Not Applicable"},{"orgOrder":0,"company":"Bioiberica","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"SPAIN","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Hyaluronic Acid","moa":"","graph1":"Musculoskeletal","graph2":"Approved","graph3":"Bioiberica","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Musculoskeletal","amount2New":0,"dosageForm":"","sponsorNew":"Bioiberica \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Bioiberica \/ Not Applicable"},{"orgOrder":0,"company":"Cayman Chemical Company Inc","sponsor":"NIDCR","pharmaFlowCategory":"D","therapeuticArea":"Musculoskeletal","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Funding","leadProduct":"Collagen","moa":"","graph1":"Musculoskeletal","graph2":"Preclinical","graph3":"Cayman Chemical Company Inc","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Musculoskeletal","amount2New":0,"dosageForm":"Implant","sponsorNew":"Cayman Chemical Company Inc \/ NIDCR","highestDevelopmentStatusID":"4","companyTruncated":"Cayman Chemical Company Inc \/ NIDCR"}]

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Hyaluronic Acid,Dermatan Sulfate,Collagen

                          Therapeutic Area : Dermatology

                          Study Phase : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : New pre-clinical study showed that Dermial® hyaluronic acid matrix ingredient increased type I collagen production by almost half – an observation not seen with standard hyaluronic acid from fermentation or extraction origin.

                          Brand Name : Dermial

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 25, 2022

                          Lead Product(s) : Hyaluronic Acid,Dermatan Sulfate,Collagen

                          Therapeutic Area : Dermatology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Bioiberica Company Banner

                          02

                          Details : The grant will be used to explore Cayman’s patented small molecule bone repair agent KMN-159 as the active pharmaceutical ingredient (API) in a drug-device combination to improve the mechanical anchorage of dental titanium implants into the jawbone.

                          Brand Name : KMN-159

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 16, 2021

                          Lead Product(s) : KMN-159,Collagen

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Preclinical

                          Sponsor : NIDCR

                          Deal Size : $1.7 million

                          Deal Type : Funding

                          Cayman

                          03

                          Beverly Hills

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                          Antibody Engineering
                          Not Confirmed

                          Beverly Hills

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                          Antibody Engineering
                          Not Confirmed

                          Details : Dermal Repair Complex helps combat the key causes of dermal breakdown — resulting in visibly firmer and more lifted skin, reduced wrinkles, enhanced radiance, and a significantly younger, healthier overall appearance.

                          Brand Name : Dermal Repair Complex

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          February 28, 2022

                          Lead Product(s) : Dimethyl Sulfone,Hyaluronic Acid,Collagen

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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