Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : SBL-001
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Preclinical
Recipient : Sable Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Sable Therapeutics and Columbia Sign Deal on Obesity Treatments
Details : The collaboration will advance a portfolio of novel polycation nanomedicines, designated as SBL-001 and SBL-002, intended to treat visceral and subcutaneous adiposity.
Brand Name : SBL-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 12, 2024
Lead Product(s) : SBL-001
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Preclinical
Recipient : Sable Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Apamistamab-I-131
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Recipient : Actinium pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Actinium Gets FDA Clearance for Iomab-ACT IND Targeting Sickle Cell Disease Conditioning
Details : The collaboration aims to advance the development of Iomab-ACT (Apamistamab-I-131) and to evaluate the safety of Iomab-ACT in patients with sickle cell disease who are to receive an allogeneic BMT.
Brand Name : Iomab-ACT
Molecule Type : Large molecule
Upfront Cash : Undisclosed
July 25, 2024
Lead Product(s) : Apamistamab-I-131
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Recipient : Actinium pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Ketamine Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase III
Recipient : NRx Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
Details : Through the agreement, NRx will focus on the NRX-100 (ketamine HCl), NMDA 3A inhibitor. It is being evaluated in Phase III clinical trial studies with patients for the treatment of Bipolar Depression and related to Suicidal Ideation.
Brand Name : NRX-100
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 19, 2023
Lead Product(s) : Ketamine Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase III
Recipient : NRx Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery
Recipient : TFC Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
TFC Therapeutics Launches to Advance Novel Platform and Technologies in Cancer Biology
Details : The agreement aims to develop a drug discovery platform that targets Tumor Macrophage Hybrid (TMH) cells to eliminate the most resilient cancers and stop disease recurrence.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 17, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery
Recipient : TFC Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : TNX-3600
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Tonix Pharmaceuticals Holding Corp
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the licensing agreement, Tonix will develop a portfolio of fully human (TNX-3600) and murine (TNX-4100) mAbs for the treatment or prophylaxis of SARS-CoV-2 infection. TNX-3600 are generated from SARS-CoV-2+ asymptomatic individuals or COVID-19 conv...
Brand Name : TNX-3600
Molecule Type : Large molecule
Upfront Cash : Undisclosed
February 13, 2023
Lead Product(s) : TNX-3600
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Tonix Pharmaceuticals Holding Corp
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Lintuzumab-Ac225,Cladribine,Cytarabine
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Actinium pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Actimab-A (lintuzumab-Ac-225) is an Actinium-225 based antibody radiation conjugate targeting CD33, a validated target that is expressed in virtually all patients with AML. Actimab-A due to its radiation modality is agnostic to cytogenetics.
Brand Name : Actimab-A
Molecule Type : Large molecule
Upfront Cash : Undisclosed
December 08, 2022
Lead Product(s) : Lintuzumab-Ac225,Cladribine,Cytarabine
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Actinium pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : ADXS-504
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Ayala Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Advaxis Updates on PI Trial of ADXS-504 for Early Prostate Cancer
Details : ADXS-504 is a novel Lm-based immunotherapy, bioengineered to elicit T cell responses against 24 tumor antigens, including 14 peptide antigens derived from hotspot mutations in patients with prostate cancer.
Brand Name : ADXS-504
Molecule Type : Vaccine
Upfront Cash : Not Applicable
June 29, 2022
Lead Product(s) : ADXS-504
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Ayala Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : RenovoRx
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RenovoRx’s lead product candidate, RenovoGem, is a combination of gemcitabine and the patented delivery system, RenovoCath®, and is regulated by the FDA as a novel oncology drug product to treat unresectable locally advanced pancreatic cancer (LAPC).
Brand Name : Gemzar
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 22, 2022
Lead Product(s) : Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : RenovoRx
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery
Recipient : BridgeBio Pharma
Deal Size : Undisclosed
Deal Type : Collaboration
Details : BridgeBio has initiated 25 collaborations with leading institutions around the world that are focused on providing therapeutic options to patients with unmet need as quickly and safely as possible.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
October 29, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery
Recipient : BridgeBio Pharma
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Ketamine Hydrochloride
Therapeutic Area : Neurology
Study Phase : Preclinical
Recipient : Silo Pharma
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the agreement, Silo has been granted an option to license psychedelics as a therapeutic currently under development, for Alzheimer’s disease.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 27, 2021
Lead Product(s) : Ketamine Hydrochloride
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Recipient : Silo Pharma
Deal Size : Undisclosed
Deal Type : Agreement
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