Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AZD1656
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Sarborg Limited
Deal Size : Inapplicable
Deal Type : Inapplicable
Conduit Progresses Phase II of its AI Initiative with Sarborg
Details : AZD1656 is a glucokinase activator small molecule drug candidate, which is currently being evaluated for the treatment of patients with lupus nephritis.
Product Name : AZD1656
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 20, 2025
Lead Product(s) : AZD1656
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Sarborg Limited
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AZD1656
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Charles River Laboratories, Inc
Deal Size : Undisclosed
Deal Type : Collaboration
Conduit Pharma, Charles River Partner on Systemic Lupus Erythematosus Model
Details : Conduit will leverage Charles River’s expertise in immunology and preclinical research to help in development of AZD1656 for Lupus Nephritis.
Product Name : AZD1656
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 13, 2025
Lead Product(s) : AZD1656
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Charles River Laboratories, Inc
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : AZD1656
Therapeutic Area : Nephrology
Study Phase : Phase II
Recipient : Sarborg
Deal Size : $2.2 million
Deal Type : Agreement
Conduit Transitions to Phase II of Sarborg Collaboration to Support AI Drug Development
Details : Conduit and Sarborg worked closely to align AI-driven processes with Conduit’s portfolio needs, enhancing the potential of key assets, including AZD1656 is being evaluated for Lupus Nephritis.
Product Name : AZD1656
Product Type : Other Small Molecule
Upfront Cash : $0.4 million
February 07, 2025
Lead Product(s) : AZD1656
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Recipient : Sarborg
Deal Size : $2.2 million
Deal Type : Agreement
Lead Product(s) : CDT1656
Therapeutic Area : Immunology
Study Phase : Phase I
Recipient : Agility Life Sciences
Deal Size : Undisclosed
Deal Type : Partnership
Conduit, Agility Life Sciences Collaborate on Autoimmune Pipeline Formulations
Details : The partnership aims to develop new solid oral-dosage form products of its autoimmune pipeline for use in future clinical trials, which includes CDT1656 for treating autoimmune diseases.
Product Name : CDT1656
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 22, 2025
Lead Product(s) : CDT1656
Therapeutic Area : Immunology
Highest Development Status : Phase I
Recipient : Agility Life Sciences
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : AZD1656
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : AstraZeneca
Deal Size : Not Applicable
Deal Type : Not Applicable
Conduit Pharma Selects Initial Indications for Autoimmune Disorder Candidate
Details : AZD1656, a HK-4 glucokinase activator, is now being repurposed by Conduit for for the treatment of systemic lupus erythematosus (including lupus nephritis) and ANCA-associated vasculitis.
Product Name : AZD1656
Product Type : Small molecule
Upfront Cash : Not Applicable
August 12, 2024
Lead Product(s) : AZD1656
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : AstraZeneca
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AZD1656
Therapeutic Area : Nephrology
Study Phase : Phase I
Recipient : AstraZeneca
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Conduit Pharmaceuticals Signs Exclusive License with AstraZeneca for Novel Treatments
Details : Through the License Agreement, Conduit will analyze existing clinical data and initiate Phase II trial studies of AZD1656 for treating Lupus Nephritis and Renal Transplant.
Product Name : AZD1656
Product Type : Small molecule
Upfront Cash : Undisclosed
August 08, 2024
Lead Product(s) : AZD1656
Therapeutic Area : Nephrology
Highest Development Status : Phase I
Recipient : AstraZeneca
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : AZD1656
Therapeutic Area : Immunology
Study Phase : Phase II
Recipient : ClinConnect
Deal Size : Undisclosed
Deal Type : Partnership
ClinConnect Partners with Conduit Pharmaceuticals on Cocrystal Development Program for AZD1656
Details : ClinConnect in partnership with Conduit, will seek to identify, characterize, and validate suitable cocrystal partners for AZD1656 to solve for current challenges associated with solubility, stability, and bioavailability.
Product Name : AZD1656
Product Type : Undisclosed
Upfront Cash : Undisclosed
October 11, 2023
Lead Product(s) : AZD1656
Therapeutic Area : Immunology
Highest Development Status : Phase II
Recipient : ClinConnect
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : AZD5904
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Murphy Canyon Acquisition
Deal Size : Undisclosed
Deal Type : Merger
Details : The combined company will accelerate development of Conduit’s autoimmune disease and idiopathic male infertility pipeline, including AZD5904, a potent orally bioavailable MPO inhibitor.
Product Name : AZD5904
Product Type : Small molecule
Upfront Cash : Undisclosed
September 22, 2023
Lead Product(s) : AZD5904
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Murphy Canyon Acquisition
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : AZD5904
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : Murphy Canyon Acquisition Corp.
Deal Size : $27.0 million
Deal Type : Private Placement
Details : AZD5904 is a potent, irreversible inhibitor of human Myeloperoxidase (MPO) that has the potential to treat idiopathic male infertility.
Product Name : AZD5904
Product Type : Small molecule
Upfront Cash : Undisclosed
November 09, 2022
Lead Product(s) : AZD5904
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : Murphy Canyon Acquisition Corp.
Deal Size : $27.0 million
Deal Type : Private Placement