[{"orgOrder":0,"company":"Conduit Pharma","sponsor":"Murphy Canyon Acquisition Corp.","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Private Placement","leadProduct":"AZD5904","moa":"","graph1":"Endocrinology","graph2":"Preclinical","graph3":"Conduit Pharma","amount2":0.029999999999999999,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Endocrinology","amount2New":0.029999999999999999,"dosageForm":"","sponsorNew":"Conduit Pharma \/ Murphy Canyon Acquisition Corp.","highestDevelopmentStatusID":"4","companyTruncated":"Conduit Pharma \/ Murphy Canyon Acquisition Corp."},{"orgOrder":0,"company":"Conduit Pharma","sponsor":"Murphy Canyon Acquisition","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Merger","leadProduct":"AZD5904","moa":"","graph1":"Endocrinology","graph2":"Phase II","graph3":"Conduit Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"","sponsorNew":"Conduit Pharma \/ Murphy Canyon Acquisition","highestDevelopmentStatusID":"8","companyTruncated":"Conduit Pharma \/ Murphy Canyon Acquisition"},{"orgOrder":0,"company":"Conduit Pharma","sponsor":"Conduit Pharma","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Partnership","leadProduct":"AZD1656","moa":"","graph1":"Immunology","graph2":"Phase II","graph3":"Conduit Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Conduit Pharma \/ Conduit Pharma","highestDevelopmentStatusID":"8","companyTruncated":"Conduit Pharma \/ Conduit Pharma"},{"orgOrder":0,"company":"Conduit Pharma","sponsor":"AstraZeneca","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"UNITED KINGDOM","productType":"Small molecule","year":"2024","type":"Licensing Agreement","leadProduct":"AZD1656","moa":"","graph1":"Nephrology","graph2":"Phase I","graph3":"Conduit Pharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"","sponsorNew":"Conduit Pharma \/ Conduit Pharma","highestDevelopmentStatusID":"6","companyTruncated":"Conduit Pharma \/ Conduit Pharma"},{"orgOrder":0,"company":"Conduit Pharma","sponsor":"AstraZeneca","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"AZD1656","moa":"","graph1":"Immunology","graph2":"Preclinical","graph3":"Conduit Pharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"","sponsorNew":"Conduit Pharma \/ AstraZeneca","highestDevelopmentStatusID":"4","companyTruncated":"Conduit Pharma \/ AstraZeneca"},{"orgOrder":0,"company":"Conduit Pharma","sponsor":"Agility Life Sciences","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2025","type":"Partnership","leadProduct":"CDT1656","moa":"Glucokinase","graph1":"Immunology","graph2":"Phase I","graph3":"Conduit Pharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Conduit Pharma \/ Conduit Pharma","highestDevelopmentStatusID":"6","companyTruncated":"Conduit Pharma \/ Conduit Pharma"},{"orgOrder":0,"company":"Conduit Pharma","sponsor":"Conduit Pharma","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Agreement","leadProduct":"AZD1656","moa":"Glucokinase","graph1":"Nephrology","graph2":"Phase II","graph3":"Conduit Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Conduit Pharma \/ Conduit Pharma","highestDevelopmentStatusID":"8","companyTruncated":"Conduit Pharma \/ Conduit Pharma"},{"orgOrder":0,"company":"Conduit Pharma","sponsor":"Charles River Laboratories, Inc","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Collaboration","leadProduct":"AZD1656","moa":"Glucokinase","graph1":"Nephrology","graph2":"Phase II","graph3":"Conduit Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Conduit Pharma \/ Charles River Laboratories, Inc","highestDevelopmentStatusID":"8","companyTruncated":"Conduit Pharma \/ Charles River Laboratories, Inc"},{"orgOrder":0,"company":"Conduit Pharma","sponsor":"Sarborg Limited","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"AZD1656","moa":"Glucokinase","graph1":"Nephrology","graph2":"Phase II","graph3":"Conduit Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Conduit Pharma \/ Sarborg Limited","highestDevelopmentStatusID":"8","companyTruncated":"Conduit Pharma \/ Sarborg Limited"}]

Find Clinical Drug Pipeline Developments & Deals by Conduit Pharma

Menu
Xls
Filters Filter
×
FILTER:
filter
Company Name
    filter

    Year

      filter

      DEALS // DEV.

        filter

        Country

          filter
          Sponsor
            filter

            Therapeutic Area

              filter

              Study Phase

                filter

                Deal Type

                  filter

                  Product Type

                    filter

                    Dosage Form

                      filter

                      Lead Product

                        filter

                        Target

                          Loading...

                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : AZD1656 is a glucokinase activator small molecule drug candidate, which is currently being evaluated for the treatment of patients with lupus nephritis.

                          Product Name : AZD1656

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 20, 2025

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Sarborg Limited

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          02

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Conduit will leverage Charles River’s expertise in immunology and preclinical research to help in development of AZD1656 for Lupus Nephritis.

                          Product Name : AZD1656

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          February 13, 2025

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Charles River Laboratories, Inc

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

                          blank

                          03

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Conduit and Sarborg worked closely to align AI-driven processes with Conduit’s portfolio needs, enhancing the potential of key assets, including AZD1656 is being evaluated for Lupus Nephritis.

                          Product Name : AZD1656

                          Product Type : Other Small Molecule

                          Upfront Cash : $0.4 million

                          February 07, 2025

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Recipient : Sarborg

                          Deal Size : $2.2 million

                          Deal Type : Agreement

                          blank

                          04

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : The partnership aims to develop new solid oral-dosage form products of its autoimmune pipeline for use in future clinical trials, which includes CDT1656 for treating autoimmune diseases.

                          Product Name : CDT1656

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 22, 2025

                          Lead Product(s) : CDT1656

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Recipient : Agility Life Sciences

                          Deal Size : Undisclosed

                          Deal Type : Partnership

                          blank

                          05

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : AZD1656, a HK-4 glucokinase activator, is now being repurposed by Conduit for for the treatment of systemic lupus erythematosus (including lupus nephritis) and ANCA-associated vasculitis.

                          Product Name : AZD1656

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 12, 2024

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : AstraZeneca

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          blank

                          06

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Through the License Agreement, Conduit will analyze existing clinical data and initiate Phase II trial studies of AZD1656 for treating Lupus Nephritis and Renal Transplant.

                          Product Name : AZD1656

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          August 08, 2024

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase I

                          Recipient : AstraZeneca

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          blank

                          07

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : ClinConnect in partnership with Conduit, will seek to identify, characterize, and validate suitable cocrystal partners for AZD1656 to solve for current challenges associated with solubility, stability, and bioavailability.

                          Product Name : AZD1656

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          October 11, 2023

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase II

                          Recipient : ClinConnect

                          Deal Size : Undisclosed

                          Deal Type : Partnership

                          blank

                          08

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : The combined company will accelerate development of Conduit’s autoimmune disease and idiopathic male infertility pipeline, including AZD5904, a potent orally bioavailable MPO inhibitor.

                          Product Name : AZD5904

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 22, 2023

                          Lead Product(s) : AZD5904

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Murphy Canyon Acquisition

                          Deal Size : Undisclosed

                          Deal Type : Merger

                          blank

                          09

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : AZD5904 is a potent, irreversible inhibitor of human Myeloperoxidase (MPO) that has the potential to treat idiopathic male infertility.

                          Product Name : AZD5904

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          November 09, 2022

                          Lead Product(s) : AZD5904

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Preclinical

                          Sponsor : Murphy Canyon Acquisition Corp.

                          Deal Size : $27.0 million

                          Deal Type : Private Placement

                          blank