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              Constant Therapeutics

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              Constant Therapeutics Announces First Patient Dosed in Phase 2 Clinical Trial of TXA127 in Ischemic Stroke Recovery

              Details:

              TXA127 (talfirastide) is a pharmaceutical formulation of the naturally occurring human peptide angiotensin-(1‐7). It is under phase 2 clinical development for ischemic stroke recovery.

              Lead Product(s): Talfirastide

              Therapeutic Area: Neurology Product Name: TXA127

              Highest Development Status: Phase II Product Type: Peptide

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable January 09, 2024

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              Constant Therapeutics

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              Constant Therapeutics TXA127 For COVID-19 To Enter NIH-Funded Clinical Trial At 60 Sites Around The U.S

              Details:

              The trial will test several compounds, each against a placebo group. The TXA127 segment will involve 300 patients treated with the peptide and will be conducted at some 60 sites nationwide.

              Lead Product(s): Angiotensin (1-7)

              Therapeutic Area: Infections and Infectious Diseases Product Name: TXA127

              Highest Development Status: Phase II Product Type: Peptide

              Partner/Sponsor/Collaborator: National Institutes of Health

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable May 12, 2021

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              Constant Therapeutics

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              Constant Therapeutics’ Promising Treatment for Covid-19 Enters Clinical Trials in Israeli Medical Centers

              Details:

              Researchers at two major medical centers in Israel, Rambam Medical Health Care Campus and Ziv Medical Center, have initiated a Phase 2 clinical trial of a promising new treatment for COVID-19. These trials are testing TXA27, a compound with an established safety profile.

              Lead Product(s): Angiotensin (1-7)

              Therapeutic Area: Infections and Infectious Diseases Product Name: TXA127

              Highest Development Status: Phase II Product Type: Peptide

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable February 24, 2021

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              Constant Therapeutics

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              Constant Therapeutics Announces Start of Phase 2 Trial of Peptide Drug TXA127 for COVID-19

              Details:

              The double-blind, placebo-controlled trial will recruit 100 patients with COVID-19 who require oxygen but are not in the ICU. The endpoints include incidence of renal failure and incidence of respiratory failure.

              Lead Product(s): Angiotensin (1-7)

              Therapeutic Area: Infections and Infectious Diseases Product Name: TXA127

              Highest Development Status: Phase II Product Type: Peptide

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable July 29, 2020

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              Constant Therapeutics

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              Constant Therapeutics' TXA127 to be Tested in Multiple Clinical Trials for COVID-19 Patients

              Details:

              Constant Therapeutics' peptide drug TXA127 will be tested in a series of Phase 2 clinical trials in hospitalized COVID-19 patients who are not in the Intensive Care Unit (ICU).

              Lead Product(s): Angiotensin (1-7)

              Therapeutic Area: Infections and Infectious Diseases Product Name: TXA127

              Highest Development Status: Phase II Product Type: Peptide

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable July 08, 2020

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              Farmhispania Group, a leading European CDMO in HPAPI Technologies & High Potency Fermentation.
              One Pharma aims to be one of the leading generic companies in Europe.
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