Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : BA3362
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : BioAtla
Deal Size : $133.5 million
Deal Type : Licensing Agreement
BioAtla and Context Partner On BA3362 Antibody Therapy Development
Details : The context will obtain from BioAtla an exclusive, worldwide license to develop, manufacture, and commercialize BA3362, Nectin-4 x CD3 TCE for the treatment of neoplasms.
Brand Name : BA3362
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 23, 2024
Lead Product(s) : BA3362
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : BioAtla
Deal Size : $133.5 million
Deal Type : Licensing Agreement
Lead Product(s) : CT-95
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : Link Immunotherapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Context Therapeutics Acquires Phase 1-ready T cell Engager CT-95
Details : Context Therapeutics acquires CT-95, a potential first-in-class mesothelin x CD3 bispecific antibody, which is ready Phase 1-ready T cell Engager for the treatment of solid tumors.
Brand Name : CT-95
Molecule Type : Large molecule
Upfront Cash : Undisclosed
July 10, 2024
Lead Product(s) : CT-95
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : Link Immunotherapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Nextech
Deal Size : $100.0 million
Deal Type : Private Placement
Context Therapeutics Announces $100 Million Private Placement
Details : The net proceeds will be used to fund the clinical development of CTIM-76, under early-stage trials for CLDN6-positive ovarian, lung, and testicular tumors.
Brand Name : CTIM-76
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 02, 2024
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Nextech
Deal Size : $100.0 million
Deal Type : Private Placement
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Context Therapeutics Announces FDA Clearance of IND for Phase 1 Trial of CTIM-76
Details : CTIM-76 is a Claudin 6 x CD3 T cell engaging bispecific antibody, which is currently being evaluated for the treatment of patients with CLDN6-positive gynecologic and testicular cancers.
Brand Name : CTIM-76
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 02, 2024
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Context Submits IND Application to Evaluate CTIM-76 in Claudin 6-Positive Cancers
Details : CTIM-76 is a CLDN6 x CD3 T cell engaging bispecific antibody. It is being evaluated for the treatment of Claudin 6-Positive gynecologic and testicular cancers.
Brand Name : CTIM-76
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 01, 2024
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CTIM-76, is a CLDN6 x CD3 bispecific antibody that incorporates a highly selective CLDN6 binding arm and a CD3 binding single-chain Fv domain in an IgG format. It is is potent with specific lysis of CLDN6+ cancer cells over normal cells.
Brand Name : CTIM-76
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 31, 2023
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Onapristone,Anastrozole
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ONA-XR (onapristone) is a selective progesterone receptor (PR) antagonist designed to block both ligand dependent and ligand-independent activity of PR which downregulates cancer stem cellmobilization, and blocking immune evasion.
Brand Name : ONA-XR
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 06, 2023
Lead Product(s) : Onapristone,Anastrozole
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Lonza Inc & Lonza America Inc
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the agreement, Lonza will support the development and manufacturing of CTIM-76, a CLDN6 x CD3 bispecific antibody clinical candidate. The bispecific antibody-based therapy is being developed to redirect T-cell mediated lysis toward malignant cells ...
Brand Name : CTIM-76
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 09, 2023
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Lonza Inc & Lonza America Inc
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Onapristone,Fulvestrant
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ONA-XR (onapristone extended release) is a potent and specific antagonist of the progesterone receptor (PR) that is orally administered. Currently, there are no approved therapies that selectively target PR+ cancers.
Brand Name : ONA-XR
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 08, 2022
Lead Product(s) : Onapristone,Fulvestrant
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Integral Molecular
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CTIM-76, a T cell-engaging bispecific antibody, as its lead clinical development candidate to target Claudin 6 (CLDN6) positive cancers.
Brand Name : CTIM-76
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 29, 2022
Lead Product(s) : CTIM-76
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Integral Molecular
Deal Size : Not Applicable
Deal Type : Not Applicable
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