Lead Product(s) : Crinecerfont
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Neurocrine Announces FDA Acceptance and Priority Review for Crinecerfont for CAH
Details : NBI-74788 (crinecerfont) is an investigational, oral, selective CRF1 antagonist, which is being evaluated for treating children, adolescents, and adults with classic congenital adrenal hyperplasia.
Brand Name : NBI-74788
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 01, 2024
Lead Product(s) : Crinecerfont
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Crinecerfont
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NBI-74788 (crinecerfont) is a CRF1 receptor inhibitor small molecule drug candidate, which is currently being evaluated for the treatment of congenital adrenal hyperplasia via oral capsule.
Brand Name : NBI-74788
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 05, 2023
Lead Product(s) : Crinecerfont
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Crinecerfont
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NBI-74788 (crinecerfont) is an investigational, oral, selective CRF1 antagonist being developed to reduce and control excess adrenal androgens through a steroid-independent mechanism for the treatment of congenital adrenal hyperplasia.
Brand Name : NBI-74788
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 05, 2023
Lead Product(s) : Crinecerfont
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Crinecerfont
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NBI-74788 (crinecerfont) s an investigational, oral, selective CRF1 antagonist being developed to reduce and control excess adrenal androgens through a steroid-independent mechanism for the treatment of congenital adrenal hyperplasia.
Brand Name : NBI-74788
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 12, 2023
Lead Product(s) : Crinecerfont
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Crinecerfont
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Changes in Adrenal and Gonadal Androgens After 14-Day Treatment with CRF1 Receptor Antagonist, Crinecerfont (NBI-74788), in Men with Classic 21-Hydroxylase Deficiency.
Brand Name : NBI-74788
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 20, 2021
Lead Product(s) : Crinecerfont
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Crinecerfont
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Phase II clinical study of crinecerfont (NBI-74788), demonstrated meaningful reductions in all three key disease hormone markers in adult patients with classic congenital adrenal hyperplasia (CAH), a genetic disorder affecting the adrenal glands.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 08, 2020
Lead Product(s) : Crinecerfont
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Crinecerfont
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Neurocrine Biosciences Provides COVID-19 Business Update
Details : Following the cancellation of the annual meeting of the Endocrine Society in March, the company plans to share the full data set from all four patient cohorts at the newly organized ENDO in June.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 03, 2020
Lead Product(s) : Crinecerfont
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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