Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Etranacogene Dezaparvovec
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
First Patients Receive Hemgenix Gene Therapy for Hemophilia B in Denmark
Details : Hemgenix (etranacogene dezaparvovec-drlb) is an AAV5 based gene therapy designed to deliver a copy of a gene encoding hFIX-Padua in patients with Hemophilia B.
Product Name : Hemgenix
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
January 21, 2025
Lead Product(s) : Etranacogene Dezaparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Human Alpha1-Proteinase Inhibitor
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
CSL Behring Expands Commitment to Alpha-1 Community with ZEMAIRA® 4- and 5-Gram Vials
Details : Zemaira is a human alpha1-proteinase inhibitor approved for augmentation and maintenance therapy in adults with Alpha-1 Antitrypsin Deficiency.
Product Name : Zemaira
Product Type : Protein
Upfront Cash : Inapplicable
February 01, 2024
Lead Product(s) : Human Alpha1-Proteinase Inhibitor
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Etranacogene Dezaparvovec
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Hemgenix (etranacogene dezaparvovec-drlb) is an AAV5 based gene therapy designed to deliver a copy of a gene encoding hFIX-Padua. Its single IV infusion results in cell transduction and increase in circulating Factor IX activity in patients with Hemophil...
Product Name : Hemgenix
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
June 20, 2023
Lead Product(s) : Etranacogene Dezaparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Immune Globulin G
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Hizentra (immune globulin subcutaneous [human] 20% liquid) supplies a broad spectrum of opsonizing and neutralizing IgG antibodies against a wide variety of bacterial and viral agents. It is indicated primary immunodeficiency and maintenance therapy in a...
Product Name : Hizentra
Product Type : Protein
Upfront Cash : Inapplicable
April 18, 2023
Lead Product(s) : Immune Globulin G
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Etranacogene Dezaparvovec
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Orsini Specialty Pharmacy
Deal Size : Undisclosed
Deal Type : Partnership
Details : Hemgenix (etranacogene dezaparvovec-drlb) is an adeno-associated virus vector-based gene therapy indicated for the treatment of adults with Hemophilia B who Currently use Factor IX prophylaxis therapy, or Have current or historical life-threatening hemor...
Product Name : Hemgenix
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 20, 2022
Lead Product(s) : Etranacogene Dezaparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Orsini Specialty Pharmacy
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Lyophilized Human C1-esterase
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In the COMPACT study, acute HAE attacks were significantly lower in the "Berinert"(Lyophilized Human C1-esterase) 60 IU/kg group at 0.52 per month compared to 4.03 per month in the placebo group (p<0.001, mixed model).
Product Name : Berinert
Product Type : Enzyme
Upfront Cash : Inapplicable
September 26, 2022
Lead Product(s) : Lyophilized Human C1-esterase
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Etranacogene Dezaparvovec
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Data from the largest gene therapy study in Hemophilia B to date shows that etranacogene dezaparvovec is statistically superior in reducing annualized bleeding rate compared to baseline FIX prophylactic therapy.
Product Name : Hemgenix
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
April 02, 2022
Lead Product(s) : Etranacogene Dezaparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Human Plasma-Derived Polyvalent Immunoglobulin G
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : HCmed Innovations
Deal Size : Undisclosed
Deal Type : Collaboration
HCmed Reaches Milestone in Immunoglobin Combination Product Development with CSL Behring
Details : CSL Behring partnered with HCmed to develop a combination product consisting of a plasma-derived immunoglobulin formulation (CSL787) administered via a customized version of the AdheResp nebulizer, HCmed's breath-actuated mesh nebulizer.
Product Name : CSL787
Product Type : Protein
Upfront Cash : Undisclosed
October 24, 2021
Lead Product(s) : Human Plasma-Derived Polyvalent Immunoglobulin G
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : HCmed Innovations
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Human Rho D Immune Globulin
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
PRIVIGEN Granted Orphan-Drug Designation
Details : CSL Behring advances Ig clinical trial program to address need in treating serious autoimmune disease.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
November 02, 2020
Lead Product(s) : Human Rho D Immune Globulin
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Apolipoprotein A-I, Human
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CSL112, Apolipoprotein A-I (Human), is a novel formulation of human plasma-derived apoA-I, the primary functional component of high-density lipoproteins (HDL).
Product Name : CSL112
Product Type : Protein
Upfront Cash : Inapplicable
October 11, 2020
Lead Product(s) : Apolipoprotein A-I, Human
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable