Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Curatis Plans USA Biologic License for C-PTBE-01 to Extend Market Protection
Details : Curatis is focusing its development activities for C-PTBE-01 on an very rare group of aggressive brain tumours (Diffuse Midline Glioma, DMG).
Brand Name : C-PTBE-01
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 14, 2024
Curatis Submits Orphan Drug Application in U.S. for Lead Candidate
Details : Curatis is focusing its development activities for C-PTBE-01 on an extremely rare group of aggressive brain tumours (diffuse midline glioma) in children.
Brand Name : C-PBTE-01
Molecule Type : Undisclosed
Upfront Cash : Not Applicable
August 27, 2024
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : ChaoDian
Deal Size : Undisclosed
Deal Type : Agreement
Details : The agreement forms the basis for discussions on the introduction, development and commercialization of KIN001, a patented combination of two APIs, pamapimod and pioglitazone, for the treatment of Idiopathic Pulmonary Fibrosis (IPF) in China.
Brand Name : KIN001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 10, 2023
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : ChaoDian
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Kinarus Therapeutics Phase 2 KINFAST Covid-19 Clinical Trial Progress Update
Details : KIN001 is a patented combination of pamapimod, a highly selective investigational small molecule inhibitor of p38 mitogen-activated protein kinase (p38 MAPK), and pioglitazone, a marketed drug for the treatment of type 2 diabetes.
Brand Name : KIN001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 21, 2023
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : KIN001 is an orally administered combination of pamapimod and pioglitazone. Pamapimod is a p38 MAPK inhibitor, whereas pioglitazone is a PPAR gamma activator. It is currently being developed in COVID-19, Idiopathic Pulmonary Fibrosis and wet Age-Related ...
Brand Name : KIN001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 16, 2023
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pamapimod
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : KIN001 is an orally available patented combination of pamapimod, a highly selective investigational small molecule inhibitor of p38 mitogen-activated protein kinase (p38 MAPK), and pioglitazone, a marketed drug for the treatment of type 2 diabetes.
Brand Name : KIN001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 06, 2022
Lead Product(s) : Pamapimod
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Ophthalmology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Kinarus Receives USPTO Notice of Allowance for Lead Therapeutic Candidate KIN001
Details : KIN001 is combination of two APIs: pamapimod and pioglitazone. Kinarus has found that combining pamapimod with pioglitazone, leads to synergistic efficacy and increased duration of action in preclinical models of wet AMD, IPF and fibrotic and inflammator...
Brand Name : KIN001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 22, 2022
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Great Health Companion Group Ltd
Deal Size : Undisclosed
Deal Type : Partnership
Kinarus Therapeutics Engages Great Health Companion Group to Explore Partnerships in China
Details : KIN001 is a patented combination of two active pharmaceutical ingredients (APIs): pamapimod and pioglitazone. Pamapimod is a highly selective clinical stage small molecule inhibitor of the p38 MAP kinase signaling pathway.
Brand Name : KIN001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 16, 2022
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Great Health Companion Group Ltd
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Kinarus Therapeutics Initiates KIN001 Phase II KINFAST Clinical Trial in COVID-19 Outpatients
Details : KIN001 is an orally administered combination of two drugs that have demonstrated synergistic antiviral and anti-inflammatory activity, as well as ability to reduce tissue fibrosis.
Brand Name : KIN001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 29, 2022
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Kinarus Therapeutics to Hold Webinar on a New Approach to Treating COVID-19
Details : KIN001 (pamapimod) is a proprietary novel combination of two active pharmaceutical ingredients that have demonstrated synergistic antiviral and anti-inflammatory activity, as well as ability to reduce tissue fibrosis in preclinical studies.
Brand Name : KIN001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 22, 2022
Lead Product(s) : Pamapimod,Pioglitazone
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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