Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AAV-ATP7A,Copper Histidine
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Preclinical
Sponsor : National Institute of Neurological Disorders and Stroke
Deal Size : $4.1 million
Deal Type : Funding
Fortress Biotech and Cyprium Announce Grant from NINDS for AAV-ATP7A Gene Therapy
Details : The funding is intended to aid in the finalization of Cyprium's primary candidate, currently undergoing preclinical trials involving AAV-ATP7A in conjunction with CUTX-101 for Menkes Disease.
Product Name : AAV-ATP7A
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 03, 2024
Lead Product(s) : AAV-ATP7A,Copper Histidine
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Preclinical
Sponsor : National Institute of Neurological Disorders and Stroke
Deal Size : $4.1 million
Deal Type : Funding
Lead Product(s) : Copper Histidine
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Sentynl Therapeutics
Deal Size : $133.5 million
Deal Type : Agreement
Details : Under the agreement, Cyprium completed the transfer of its proprietary rights and assigned its FDA documents pertaining to CUTX-101 (copper histidinate) product candidate for the treatment of Menkes disease, to Sentynl.
Product Name : CUTX-101
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Undisclosed
June 12, 2023
Lead Product(s) : Copper Histidine
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Sentynl Therapeutics
Deal Size : $133.5 million
Deal Type : Agreement
Lead Product(s) : Copper Histidine
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Fortress Biotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CUTX-101, a subcutaneous injectable formulation of Copper Histidinate has potential to be first FDA-approved treatment for Menkes disease; rolling submission of New Drug Application to FDA is ongoing and expected to be completed in mid-year 2022.
Product Name : CUTX-101
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
March 21, 2022
Lead Product(s) : Copper Histidine
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Fortress Biotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Copper Histidine
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Sentynl Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Cyprium Therapeutics and Sentynl Therapeutics Sign Development and Asset Purchase Agreement
Details : Sentynl has signed an agreement with Cyprium to contribute research funding for CUTX-101, a Copper Histidinate product candidate for the treatment of Menkes disease, and to purchase Cyprium's proprietary rights to CUTX-101.
Product Name : CUTX-101
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : $20.0 million
February 24, 2021
Lead Product(s) : Copper Histidine
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Sentynl Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition