[{"orgOrder":0,"company":"Cyrus Biotechnology","sponsor":"Selecta Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Large molecule","year":"2021","type":"Collaboration","leadProduct":"IL-2 Mutein","moa":"IL-2 receptor","graph1":"Immunology","graph2":"Preclinical","graph3":"Cyrus Biotechnology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"","sponsorNew":"Cyrus Biotechnology \/ Selecta Bioscience","highestDevelopmentStatusID":"4","companyTruncated":"Cyrus Biotechnology \/ Selecta Bioscience"},{"orgOrder":0,"company":"Cyrus Biotechnology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Inapplicable","leadProduct":"CYR212","moa":"IgG level","graph1":"Immunology","graph2":"Preclinical","graph3":"Cyrus Biotechnology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Cyrus Biotechnology \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Cyrus Biotechnology \/ Inapplicable"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          BIO CEO & Investor
                          Not Confirmed
                          BIO CEO & Investor
                          Not Confirmed

                          Details : CYR212 to deplete circulating IgG, it has the potential to be the first approved IgG-lowering agent in myasthenia gravis and immune thrombocytopenia.

                          Product Name : CYR212

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 09, 2025

                          Lead Product(s) : CYR212

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          BIO CEO & Investor
                          Not Confirmed
                          BIO CEO & Investor
                          Not Confirmed

                          Details : ImmTOR in combination with Treg-selective IL-2 mutant protein (IL-2 “mutein”) demonstrate substantial synergistic activity in increasing percentage and durability of Treg expansion for treatment of autoimmune diseases and other deleterious immune con...

                          Product Name : Undisclosed

                          Product Type : Large molecule

                          Upfront Cash : Undisclosed

                          September 08, 2021

                          Lead Product(s) : IL-2 Mutein

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Selecta Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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