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Find Clinical Drug Pipeline Developments & Deals by Cytovance Biologics

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                          01

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : GTB-3650 is the Company's lead second-generation Tri-Specific Killer Engager TriKE ® program currently in preclinical development for the treatment of relapsed/refractory acute myelogenous leukemia (AML) and high-risk myelodysplastic syndrome (MDS).

                          Brand Name : GTB-3650

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          August 30, 2022

                          Lead Product(s) : GTB-3650

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : GT Biopharma

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          02

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Previously, the lead candidate GTB-3550 TriKE™ was manufactured at the University of Minnesota's GMP manufacturing center. GT Biopharma expanded GMP manufacturing agreement with Cytovance Biologics for the manufacture of all TriKEs™.

                          Brand Name : GTB-3550 TriKE

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          February 18, 2021

                          Lead Product(s) : GTB-3550 TriKE

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : GT Biopharma

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          03

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Under the terms of the partnership agreement, Cytovance will be the exclusive GMP manufacture for three of the Company's TriKE™ therapeutic product candidates.

                          Brand Name : GTB-3550

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          October 06, 2020

                          Lead Product(s) : GTB-3550

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : GT Biopharma

                          Deal Size : $6.0 million

                          Deal Type : Partnership

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                          04

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Collaboration to focus on using Akshaya’s proprietary Chimigen® Platform Technology to execute bulk drug products of both COVID-19 and HBV vaccines to be used in Phase I clinical trials by Cytovance.

                          Brand Name : Undisclosed

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          April 23, 2020

                          Lead Product(s) : COVID-19 vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Recipient : Akshaya Bio

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : The companies will focus on preparing sufficient quantities of GT's Covid-19 TriKE drug product for preclinical evaluation using Cytovance's E. coli-based Keystone Expression System.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          March 10, 2020

                          Lead Product(s) : OXS-3550

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : GT Biopharma

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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