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Pharmaceutical","highestDevelopmentStatusID":"8","companyTruncated":"Daewoong Pharmaceutical \/ Daewoong Pharmaceutical"},{"orgOrder":0,"company":"Daewoong Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"SOUTH KOREA","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"DWN12088","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Daewoong Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Daewoong Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Daewoong Pharmaceutical \/ Not Applicable"}]

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                          01

                          Antibody Engineering
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                          Antibody Engineering
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                          Details : DWN12088 (bersiporocin) is a first-in-class prolyl-tRNA synthetase inhibitor, which is being evaluated in phase 2 clinical trials for the treatment of idiopathic pulmonary fibrosis.

                          Brand Name : DWN12088

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 29, 2024

                          Lead Product(s) : DWN12088

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The proceeds will support late-stage clinical development of ABP-450, a botulinum toxin type-A complex for episodic migraine treatment.

                          Brand Name : ABP-450

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          March 19, 2024

                          Lead Product(s) : PrabotulinumtoxinA

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Recipient : AEON Biopharma

                          Deal Size : $15.0 million

                          Deal Type : Private Placement

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : DWN12088 (bersiporocin) is a first-in-class prolyl-tRNA synthetase inhibitor, which is being evaluated in phase 2 clinical trials for the treatment of idiopathic pulmonary fibrosis.

                          Brand Name : DWN12088

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 29, 2024

                          Lead Product(s) : DWN12088

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Under the terms of the agreement, Zydus will assume full responsibility for the clinical development and commercialization for leuprolide injectable in the US market, and Daewoong will be responsible for the pre-clinical studies, production and supply of...

                          Brand Name : Lupron Depot-Generic

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          December 12, 2023

                          Lead Product(s) : Leuprolide Acetate

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Zydus Lifesciences

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The microneedle patch within the Semaglutide series, a GLP-1 analogue, using its proprietary 'CLOPAM' (Closed-Packed Aeroperssured Microneedle) platform, used for the treatment of Obesity.

                          Brand Name : Undisclosed

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          November 06, 2023

                          Lead Product(s) : Semaglutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : HL192 (ATH-399A) is a first-in-class small molecule that focuses on activating Nurr1, a master regulator associated with the development and maintenance of dopaminergic neurons, for the potential treatment of Parkinson's Disease.

                          Brand Name : HL192

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 12, 2023

                          Lead Product(s) : HL192

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Recipient : Hanall Biopharma

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : DWRX2008 is an innovative nanoparticle eyedrop adaptation of Envlo®(enavogliflozin), which tackles the challenge of poor retinal drug absorption from oral use, which is investigated for Diabetic Retinopathy and Macular Edema.

                          Brand Name : DWRX2008

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 25, 2023

                          Lead Product(s) : Enavogliflozin

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Daewoong Pharmaceutical has added benign masseteric hypertrophy (BMH), commonly known as the square jaw, to the indications for its botulinum toxin (BTX) product, Nabota.

                          Brand Name : Nabota

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 28, 2023

                          Lead Product(s) : Botulinum toxin type A

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Under the agreement, Daewoong Pharmaceutical plans to expand its presence of a potassium-competitive acid blocker (P-CAB) drug Fexuclue (fexuprazan) in the African pharmaceutical market for gastroesophageal reflux disease (GERD).

                          Brand Name : Fexuclue

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          July 26, 2023

                          Lead Product(s) : Fexuprazan

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Approved

                          Sponsor : COOPER PHARMA

                          Deal Size : $20.3 million

                          Deal Type : Licensing Agreement

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                          10

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Under the terms of the termination agreement, Daewoong regains all rights to the commercialization and clinical development of Fexuclue (fexuprazan), a novel potassium-competitive acid blocker for the treatment of erosive esophagitis, in the U.S. and Can...

                          Brand Name : Fexuclue

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 05, 2023

                          Lead Product(s) : Fexuprazan

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Approved

                          Sponsor : Neurogastrx

                          Deal Size : Undisclosed

                          Deal Type : Termination

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