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    [{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Not Applicable","leadProduct":"Brexucabtagene autoleucel","moa":"CD19","graph1":"Oncology","graph2":"Approved","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Suspension for Intravenous Infusion","sponsorNew":"Dana-Farber Cancer Institute \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Dana-Farber Cancer Institute \/ Not Applicable"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Kazia Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Collaboration","leadProduct":"Paxalisib","moa":"PI3-kinase class I","graph1":"Oncology","graph2":"Undisclosed","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Dana-Farber Cancer Institute \/ Kazia Therapeutics","highestDevelopmentStatusID":"1","companyTruncated":"Dana-Farber Cancer Institute \/ Kazia Therapeutics"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Not Applicable","leadProduct":"Axicabtagene Ciloleucel","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Dana-Farber Cancer Institute \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Dana-Farber Cancer Institute \/ Not Applicable"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"BrainStorm Cell Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Not Applicable","leadProduct":"Autologous MSC-NTF cells","moa":"","graph1":"Neurology","graph2":"Phase III","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intrathecal Injection","sponsorNew":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute","highestDevelopmentStatusID":"10","companyTruncated":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Hale Family Center for Pancreatic Cancer Research","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Funding","leadProduct":"Undisclosed","moa":"","graph1":"Oncology","graph2":"Discovery","graph3":"Dana-Farber Cancer Institute","amount2":0.080000000000000002,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0.080000000000000002,"dosageForm":"","sponsorNew":"Dana-Farber Cancer Institute \/ Hale Family Center for Pancreatic Cancer Research","highestDevelopmentStatusID":"2","companyTruncated":"Dana-Farber Cancer Institute \/ Hale Family Center for Pancreatic Cancer Research"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"SpringWorks Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Collaboration","leadProduct":"Nirogacestat Hydrobromide","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Dana-Farber Cancer Institute \/ SpringWorks Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Dana-Farber Cancer Institute \/ SpringWorks Therapeutics"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Biohaven Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Not Applicable","leadProduct":"KP1237","moa":"CD38","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute","highestDevelopmentStatusID":"7","companyTruncated":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"EpicentRx","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"RRx-001","moa":"","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute","highestDevelopmentStatusID":"8","companyTruncated":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Hillstream BioPharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Agreement","leadProduct":"HSB-1216","moa":"","graph1":"Oncology","graph2":"IND Enabling","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute","highestDevelopmentStatusID":"5","companyTruncated":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"ImmunityBio","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Not Applicable","leadProduct":"Cytokine Induced Memory-Like Natural Killer Cell","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute","highestDevelopmentStatusID":"6","companyTruncated":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Invios","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"AUSTRIA","productType":"Small molecule","year":"2023","type":"Collaboration","leadProduct":"INV501","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute","highestDevelopmentStatusID":"4","companyTruncated":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Effector Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Collaboration","leadProduct":"Zotatifin","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute","highestDevelopmentStatusID":"8","companyTruncated":"Dana-Farber Cancer Institute \/ Dana-Farber Cancer Institute"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Red Queen Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Peptide","year":"2024","type":"Licensing Agreement","leadProduct":"RQ-01","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"Dana-Farber Cancer Institute \/ Red Queen Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Dana-Farber Cancer Institute \/ Red Queen Therapeutics"},{"orgOrder":0,"company":"Dana-Farber Cancer Institute","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2025","type":"Inapplicable","leadProduct":"NEO-PV-01","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intradermal Injection","sponsorNew":"Dana-Farber Cancer Institute \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Dana-Farber Cancer Institute \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Dana-Farber Cancer Institute

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                            01

                            Dana-Farber Cancer Institute

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                            Dana-Farber Cancer Institute

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                            Lead Product(s) : NEO-PV-01,Ipilimumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cancer Vaccine Shows Promise for Patients with Stage III and IV Kidney Cancer

                            Details : NeoVax is a combination of neoantigen peptides and poly-ICLC which is being evaluated in combination with ipilimumab for the treatment of renal cell carcinoma.

                            Product Name : NeoVax

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            February 06, 2025

                            Lead Product(s) : NEO-PV-01,Ipilimumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Dana-Farber Cancer Institute

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                            Lead Product(s) : RQ-01

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Red Queen Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Red Queen Expands License Agreement, Advances Pan-Influenza Program

                            Details : Dana-Farber grants Red Queen exclusive license to stapled lipopeptide COVID-19 therapeutics, incorporates additional exclusive patent rights covering RSV therapeutics.

                            Product Name : Undisclosed

                            Product Type : Peptide

                            Upfront Cash : Undisclosed

                            December 03, 2024

                            Lead Product(s) : RQ-01

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Red Queen Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            03

                            Dana-Farber Cancer Institute

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                            Lead Product(s) : Zotatifin

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Recipient : Effector Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            eFFECTOR and Dana-Farber to Evaluate Zotatifin in ER+ Endometrial Cancer

                            Details : The collaboration aims to conduct an investigator-sponsored trial evaluating zotatifin in patients with estrogen receptor-positive endometrial cancer and low-grade serous ovarian cancer.

                            Product Name : eFT226

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            May 20, 2024

                            Lead Product(s) : Zotatifin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Recipient : Effector Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            04

                            Dana-Farber Cancer Institute

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                            Lead Product(s) : INV501

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Invios

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            invIOs and Dana-Farber Cancer Institute Start Collaboration to Study Novel Small Molecule INV501 for Treatment...

                            Details : The collaboration aims to evaluate invIOs’ small molecule INV501 that can selectively enhance anti-tumor immune responses, as a potential treatment for glioblastoma.

                            Product Name : INV501

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            November 09, 2023

                            Lead Product(s) : INV501

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Invios

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            05

                            Dana-Farber Cancer Institute

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                            Dana-Farber Cancer Institute

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                            Lead Product(s) : Cytokine Induced Memory-Like Natural Killer Cell,Nogapendekin alfa Inbakicept

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : ImmunityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Phase 1 Study Indicates Allogeneic Cytokine-Induced Memory-Like Natural Killer Cells Plus N-803 May Induce Tum...

                            Details : Anktiva™ (N-803 ), a lead cytokine fusion protein, is a novel IL-15 superagonist complex and which is investigated for advanced Head-and-Neck Cancer Patients.

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            July 10, 2023

                            Lead Product(s) : Cytokine Induced Memory-Like Natural Killer Cell,Nogapendekin alfa Inbakicept

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : ImmunityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Dana-Farber Cancer Institute

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                            Lead Product(s) : HSB-1216

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Recipient : Hillstream BioPharma

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Hillstream BioPharma Signs an Exclusive Option Agreement to Advance Next-Generation Anti-MUC1-C Agents for Dru...

                            Details : Dana-Farber has granted under an exclusive option agreement to Hillstream Biopharma Inc., to develop anti-MUC1-C antibodies to selectively deliver Hillstream’s Quatramer-based lead candidate HSB-1216 targeting CSC by the induction of ferroptosis.

                            Product Name : HSB-1216

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            January 31, 2023

                            Lead Product(s) : HSB-1216

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Recipient : Hillstream BioPharma

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            07

                            Dana-Farber Cancer Institute

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                            Dana-Farber Cancer Institute

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                            Lead Product(s) : RRx-001,Cisplatin

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Recipient : EpicentRx

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            EpicentRx Announces Poster Presentation for Phase 2 Randomized Clinical Trial with RRx-001 as an Anti-Mucositi...

                            Details : RRx-001 leads EpicentRx's CyNRGY platform as a first-in-class investigational treatment sourced from an exclusively licensed portfolio of aerospace-derived small molecules.

                            Product Name : RRx-001

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 01, 2022

                            Lead Product(s) : RRx-001,Cisplatin

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Recipient : EpicentRx

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Dana-Farber Cancer Institute

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                            Dana-Farber Cancer Institute

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                            Lead Product(s) : KP1237,Autologous Cytokine Induced Memory-Like NK Cell

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Biohaven Pharmaceuticals

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Biohaven Enrolls Phase 1a/1b Clinical Trial of BHV-1100, Lead Asset from its ARM™ (Antibody Recruiting Molec...

                            Details : BHV-1100 targets the destruction of CD38-expressing cells in combination with autologous cytokine induced memory-like (CIML) natural killer (NK) cells and immune globulin (Ig) in multiple myeloma patients undergoing autologous stem cell transplant.

                            Product Name : BHV-1100

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            October 27, 2021

                            Lead Product(s) : KP1237,Autologous Cytokine Induced Memory-Like NK Cell

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Biohaven Pharmaceuticals

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Dana-Farber Cancer Institute

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                            Dana-Farber Cancer Institute

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                            Lead Product(s) : Nirogacestat Hydrobromide,Anti-B-cell Maturation Antigen

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : SpringWorks Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            SpringWorks Therapeutics Enters Into Research Collaboration with Leading Cancer Institute to Evaluate Nirogace...

                            Details : The collaboration is designed to further investigate nirogacestat, SpringWorks’ investigational gamma-secretase inhibitor (GSI), with anti-B-cell maturation antigen (BCMA) agents in a variety of preclinical multiple myeloma models.

                            Product Name : PF-03084014

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            August 30, 2021

                            Lead Product(s) : Nirogacestat Hydrobromide,Anti-B-cell Maturation Antigen

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : SpringWorks Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            10

                            Dana-Farber Cancer Institute

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Hale Family Center for Pancreatic Cancer Research

                            Deal Size : $80.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Dana-Farber Receives $50 million Funding to Study Pancreatic Cancer

                            Details : Funding will enable a wide range of ambitious work in two main areas of pancreatic cancer research: early detection and prevention, and precision medicine and biology.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            May 11, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Hale Family Center for Pancreatic Cancer Research

                            Deal Size : $80.0 million

                            Deal Type : Funding

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