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Applicable","leadProduct":"Dapagliflozin","moa":"","graph1":"Endocrinology","graph2":"Approved","graph3":"AstraZeneca","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"","sponsorNew":"AstraZeneca \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"AstraZeneca \/ Not Applicable"},{"orgOrder":0,"company":"Akums Lifesciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"INDIA","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Dapagliflozin","moa":"||SGLT2","graph1":"Endocrinology","graph2":"Approved FDF","graph3":"Akums Lifesciences","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Akums Lifesciences \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Akums Lifesciences \/ Inapplicable"},{"orgOrder":0,"company":"Nectar Lifecare","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"INDIA","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Dapagliflozin","moa":"SGLT2","graph1":"Endocrinology","graph2":"Approved FDF","graph3":"Nectar Lifecare","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Nectar Lifecare \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Nectar Lifecare \/ Inapplicable"},{"orgOrder":0,"company":"Mascot Health","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"INDIA","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Glimepiride","moa":"||SUR 1\/Kir6.2","graph1":"Endocrinology","graph2":"Approved FDF","graph3":"Mascot Health","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Oral Tablet, Extended Release","sponsorNew":"Mascot Health \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Mascot Health \/ Inapplicable"}]

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01

Lead Product(s) : Dapagliflozin

Therapeutic Area : Endocrinology

Study Phase : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

Details : Mankind Pharma has launched Justoza, a Dapagliflozin brand marketed by Mankind to treat diabetes, heart failure and chronic kidney disease. Launching API DMF grade dapagliflozin is an innovative futuristic approach to provide the best in class quality to...

Product Name : Justoza

Product Type : Small molecule

Upfront Cash : Not Applicable

June 22, 2021

Lead Product(s) : Dapagliflozin

Therapeutic Area : Endocrinology

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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02

Next-Gen Conjugates
Not Confirmed
Next-Gen Conjugates
Not Confirmed

Details : Dapnec (dapagliflozin) is a SGLT2 inhibitor small molecule drug candidate, which is indicated for the treatment of Type 2 diabetes.

Product Name : Dapnec

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

February 18, 2025

Lead Product(s) : Dapagliflozin

Therapeutic Area : Endocrinology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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03

Next-Gen Conjugates
Not Confirmed
Next-Gen Conjugates
Not Confirmed

Details : Akums launched apagliflozin and pioglitazone combination tablets, which acts as a dual-action therapy. It is indicated for diabetes management.

Product Name : Undisclosed

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

February 04, 2025

Lead Product(s) : Dapagliflozin,Pioglitazone

Therapeutic Area : Endocrinology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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04

Next-Gen Conjugates
Not Confirmed
Next-Gen Conjugates
Not Confirmed

Details : Farxiga (dapagliflozin), is first-in-class, oral, USFDA approved, once-daily SGLT2 inhibitor, for paediatric patients with type-2 diabetes aged 10 years and older.

Product Name : Farxiga

Product Type : Small molecule

Upfront Cash : Not Applicable

June 12, 2024

Lead Product(s) : Dapagliflozin

Therapeutic Area : Endocrinology

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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05

Next-Gen Conjugates
Not Confirmed
Next-Gen Conjugates
Not Confirmed

Details : Dapagliflozin, metformin and glimepiride fixed dose combination is approved for the treatment of patients with type 2 diabetes.

Product Name : Undisclosed

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

December 11, 2023

Lead Product(s) : Glimepiride,Dapagliflozin,Metformin

Therapeutic Area : Endocrinology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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06

Next-Gen Conjugates
Not Confirmed
Next-Gen Conjugates
Not Confirmed

Details : DSR 2.0 (icodextrin, dextrose, dapagliflozin) is an implant small molecule drug combination, currently being investigated for heart failure management.

Product Name : DSR 2.0

Product Type : Small molecule

Upfront Cash : Not Applicable

November 29, 2023

Lead Product(s) : Icodextrin,Dextrose,Dapagliflozin

Therapeutic Area : Cardiology/Vascular Diseases

Highest Development Status : Phase I/ Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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07

Next-Gen Conjugates
Not Confirmed
Next-Gen Conjugates
Not Confirmed

Details : Zibotentan/dapagliflozin combination leverages SGLT2 inhibition and high selectivity ETA receptor antagonism. It is being evaluated in phase 2 clinical trials for the treatment of chronic kidney disease and proteinuria.

Product Name : ZD4054

Product Type : Small molecule

Upfront Cash : Not Applicable

November 03, 2023

Lead Product(s) : Zibotentan,Dapagliflozin

Therapeutic Area : Nephrology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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08

Next-Gen Conjugates
Not Confirmed
Next-Gen Conjugates
Not Confirmed

Details : Zita DM contains the DPP4 inhibitor, Teneligliptin, the SGLT2 inhibitor, Dapagliflozin, and Metformin SR in a fixed dose. It must be taken once daily, under prescription, to improve glycemic control in patients with Type 2 diabetes.

Product Name : Zita DM

Product Type : Small molecule

Upfront Cash : Not Applicable

October 18, 2023

Lead Product(s) : Teneligliptin Hydrobromide,Dapagliflozin,Metformin

Therapeutic Area : Endocrinology

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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09

Next-Gen Conjugates
Not Confirmed
Next-Gen Conjugates
Not Confirmed

Details : Forxiga (dapagliflozin) is an inhibitor of SGLT2. By inhibiting SGLT2, which is investigated for the treatment of children and adolescents with type 2 diabetes.

Product Name : Forxiga

Product Type : Small molecule

Upfront Cash : Not Applicable

October 04, 2023

Lead Product(s) : Dapagliflozin

Therapeutic Area : Endocrinology

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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10

Next-Gen Conjugates
Not Confirmed
Next-Gen Conjugates
Not Confirmed

Details : Forxiga (dapagliflozin) is an inhibitor of SGLT2. By inhibiting SGLT2, it is indicated to reduce the risk of cardiovascular death, hospitalisation for HF, or urgent HF visits in adults with symptomatic chronic heart failure.

Product Name : Forxiga

Product Type : Small molecule

Upfront Cash : Not Applicable

August 18, 2023

Lead Product(s) : Dapagliflozin

Therapeutic Area : Cardiology/Vascular Diseases

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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