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    [{"orgOrder":0,"company":"Olatec Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Dapansutrile","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Olatec Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"Olatec Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Olatec Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Olatec Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Dapansutrile","moa":"NLRP3","graph1":"Neurology","graph2":"Preclinical","graph3":"Olatec Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"oral","sponsorNew":"Olatec Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Olatec Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Olatec Therapeutics","sponsor":"Sanders Morris Harris","pharmaFlowCategory":"D","therapeuticArea":"Rheumatology","country":"","productType":"Small molecule","year":"2023","type":"Series A Financing","leadProduct":"Dapansutrile","moa":"","graph1":"Rheumatology","graph2":"Phase II\/ Phase III","graph3":"Olatec Therapeutics","amount2":0.040000000000000001,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Rheumatology","amount2New":0.040000000000000001,"dosageForm":"Tablet","sponsorNew":"Olatec Therapeutics \/ Sanders Morris Harris","highestDevelopmentStatusID":"9","companyTruncated":"Olatec Therapeutics \/ Sanders Morris Harris"},{"orgOrder":0,"company":"Olatec Therapeutics","sponsor":"The Michael J. Fox Foundation","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2023","type":"Funding","leadProduct":"Dapansutrile","moa":"","graph1":"Neurology","graph2":"Phase I","graph3":"Olatec Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Olatec Therapeutics \/ The Michael J. Fox Foundation","highestDevelopmentStatusID":"6","companyTruncated":"Olatec Therapeutics \/ The Michael J. Fox Foundation"},{"orgOrder":0,"company":"Olatec Therapeutics","sponsor":"Merck & Co","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Dapansutrile","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Olatec Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Olatec Therapeutics \/ Merck & Co. Inc.","highestDevelopmentStatusID":"7","companyTruncated":"Olatec Therapeutics \/ Merck & Co. Inc."},{"orgOrder":0,"company":"Olatec Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Dapansutrile","moa":"","graph1":"Neurology","graph2":"Phase I","graph3":"Olatec Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Olatec Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Olatec Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Olatec Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Dapansutrile","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Olatec Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Olatec Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Olatec Therapeutics \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals for Dapansutrile

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                            01

                            Olatec Therapeutics

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                            Olatec Therapeutics

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                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            First Patient Enrolled in Phase 2 Study of Dapansutrile for Type 2 Diabetes

                            Details : OLT1177 (dapansutrile) is an oral NLRP3 Inhibitor small molecule drug candidate, which is being evaluated for the treatment of patients with type 2 diabetes mellitus.

                            Brand Name : OLT1177

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 11, 2024

                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Olatec Therapeutics

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                            Olatec Therapeutics

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                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Olatec Therapeutics to Conduct Phase 2 Trial in Patients with Early Parkinson’s Disease

                            Details : OLT1177 (dapansutrile) is an oral NLRP3 Inhibitor, which is being evaluated for the treatment of patients with early parkinson’s disease.

                            Brand Name : OLT1177

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 20, 2024

                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Olatec Therapeutics

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                            Lead Product(s) : Dapansutrile,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Olatec Therapeutics Announces the Completion of First Dose Cohort in an Innovative Trial Investigating Olatecâ...

                            Details : OLT1177 (dapansutrile) is an NLRP3 inhibitor which is being investigated in combination with pembrolizumab (Keytruda®) in patients with PD-1 refractory advanced melanoma.

                            Brand Name : OLT1177

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 16, 2023

                            Lead Product(s) : Dapansutrile,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Olatec Therapeutics

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                            Olatec Therapeutics

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                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : The Michael J. Fox Foundation

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Olatec Therapeutics Awarded a Grant from The Michael J. Fox Foundation in Collaboration With Medical Universit...

                            Details : The Michael J. Fox Foundation for Parkinson’s Research has awarded a grant from their Therapeutics Pipeline Program to support preclinical research evaluating Olatec Therapeutics’ lead compound, OLT1177 (dapansutrile), an investigational small molecu...

                            Brand Name : OLT1177

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            March 10, 2023

                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : The Michael J. Fox Foundation

                            Deal Size : Undisclosed

                            Deal Type : Funding

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                            05

                            Olatec Therapeutics

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                            Olatec Therapeutics

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                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Sanders Morris Harris

                            Deal Size : $40.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Olatec Therapeutics Announces the Final Closing, Led by Sanders Morris Harris, on Its $40 Million Series A Fin...

                            Details : The net proceeds will be used to advance OLT1177 (dapansutrile) into later stage clinical development. Dapansutrile is an investigational small molecule, that specifically binds to and blocks NLRP3, the sensor molecule integral in the formation of the NL...

                            Brand Name : OLT1177

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 23, 2023

                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Sanders Morris Harris

                            Deal Size : $40.0 million

                            Deal Type : Series A Financing

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                            06

                            Olatec Therapeutics

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                            Olatec Therapeutics

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                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Olatec Therapeutics’ Dapansutrile Prevents the Inflammatory Response, Restores Cognitive and Behavioral Defi...

                            Details : Results suggest a potential therapeutic benefit for dapansutrile in patients with neuroinflammatory diseases, e.g., Alzheimer’s Disease. Preclinical results encourage clinical research with dapansutrile in Alzheimer’s Disease to investigate therapeut...

                            Brand Name : OLT1177

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 29, 2020

                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Olatec Therapeutics

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                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Olatec Therapeutics Enrolls its First Patients in a Phase 2 Clinical Trial in COVID-19 with its Selective NLRP...

                            Details : The trial will evaluate the safety and efficacy of dapansutrile in approximately 80 ambulatory patients from diverse demographics, randomized 1:1 (dapansutrile:placebo) and treated for 14 days.

                            Brand Name : OLT1177

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 27, 2020

                            Lead Product(s) : Dapansutrile

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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