Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Neuroplastogen
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Discovery
Sponsor : U.S. Department of Defense
Deal Size : $0.8 million
Deal Type : Funding
Delix Awarded Grant from US Department of Defense for Neuroplastogen to Treat Hearing Loss
Details : The financing will support the advancement of a neuroplastogen, a novel, first-in-class, non-toxic, that has been found to repair cochlear synaptopathy that contribute to hidden hearing loss.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 04, 2024
Lead Product(s) : Neuroplastogen
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Discovery
Sponsor : U.S. Department of Defense
Deal Size : $0.8 million
Deal Type : Funding
Lead Product(s) : DLX-001
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Delix Reports DLX-001 Shows CNS Penetration Without Psychotomimetic Effects
Details : DLX-001 is the first of several psychoplastogens promoting rapid neuroplasticity without hallucinatory responses, being investigated for major depressive disorder (MDD).
Brand Name : DLX-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 13, 2024
Lead Product(s) : DLX-001
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : DLX-007
Therapeutic Area : Psychiatry/Psychology
Study Phase : IND Enabling
Sponsor : National Institutes of Health
Deal Size : $0.3 million
Deal Type : Funding
Details : The grant will support further development of novel neuroplastogen and ibogaine analog, DLX-007, a novel, first-in-class, neuroplastogen being evaluated in a range of substance use disorders (SUDs), including opioid and stimulant use.
Brand Name : DLX-007
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 13, 2023
Lead Product(s) : DLX-007
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : IND Enabling
Sponsor : National Institutes of Health
Deal Size : $0.3 million
Deal Type : Funding
Lead Product(s) : DLX-001
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : DLX-001 is the first of several psychoplastogens to be approved for human trials. It promotes rapid and enduring neuroplasticity, matching or exceeding the efficacy of natural psychedelic compounds, without hallucinatory responses even at high doses.
Brand Name : DLX-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 20, 2023
Lead Product(s) : DLX-001
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : DLX-001
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Delix Therapeutics Initiates Phase I Trial for Novel Compound DLX-001
Details : DLX-001 is the first of several psychoplastogens to be approved for human trials. It promotes rapid and enduring neuroplasticity, matching or exceeding the efficacy of natural psychedelic compounds, without hallucinatory responses even at high doses.
Brand Name : DLX-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 09, 2023
Lead Product(s) : DLX-001
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Recipient : Cellectricon
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Delix have partnered with Cellectricon to create novel assays to measure the structural and functional plasticity effects of Delix's psychoplastogen compounds using cutting-edge technologies.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 14, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Recipient : Cellectricon
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : DLX-7
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : National Institute on Drug Abuse
Deal Size : Undisclosed
Deal Type : Partnership
Details : Under the partnership, The National Institute on Drug Abuse (NIDA) will test one of Delix's lead clinical candidates DLX-7, non-hallucinogenic and non-toxic ibogaine analog, for use in treating a range of substance use disorders.
Brand Name : DLX-7
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 07, 2021
Lead Product(s) : DLX-7
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : National Institute on Drug Abuse
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : DLX-1
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : ARTIS Ventures
Deal Size : $70.0 million
Deal Type : Series A Financing
Details : The Company expects to use the proceeds to advance two lead candidates through Phase 1 clinical trials, DLX-1 and DLX-7, which are currently undergoing pre-IND safety and toxicology studies to enable clinical trials.
Brand Name : DLX-1
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 27, 2021
Lead Product(s) : DLX-1
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : ARTIS Ventures
Deal Size : $70.0 million
Deal Type : Series A Financing
Lead Product(s) : AAZ
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The paper reveals DLX-1—a new compound inspired by the chemical structures of common psychedelic substances that demonstrates sustained antidepressant effects but without hallucinogenic properties.
Brand Name : DLX-1
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 28, 2021
Lead Product(s) : AAZ
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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