Lead Product(s) : Difelikefalin
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Cara Therapeutics: Outcome of KOURAGE-1 Study on Oral Difelikefalin in Notalgia
Details : Korsuva (difelikefalin) is a kappa opioid receptor agonists. Its oral formulation is under development for the treatment of moderate-to-severe pruritus in adult patients with notalgia paresthetica.
Brand Name : Korsuva
Molecule Type : Peptide
Upfront Cash : Not Applicable
June 12, 2024
Lead Product(s) : Difelikefalin
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Izokibep
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : IMG-020 (izokibep) is a small therapeutic protein inhibitor of interleukin-17A (IL-17A). It is designed to overcome monoclonal antibodies limitations for hidradenitis suppurativa indication. It is being investigated for moderate-to-severe Hidradenitis.
Brand Name : IMG-020
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 11, 2023
Lead Product(s) : Izokibep
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Coacillium
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : LH-8 (coacillium) is an investigational botanical drug and is the first and only drug candidate for alopecia areata in children and adolescents with both moderate and severe forms of the disease.
Brand Name : LH-8
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 19, 2023
Lead Product(s) : Coacillium
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : $1.2 million
Deal Type : Private Placement
Devonian Announces Closing of a Private Placement of $1.2 Million
Details : The proceeds will fund the preparation of clinical study programs for PUR0110 (thykamine) in phase 2/3 program of pediatric atopic dermatitis, phase 2 programs of radiodermatitis associated with radiotherapy and in Hand and Foot Syndrome and associated w...
Brand Name : PUR0110
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 06, 2023
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : $1.2 million
Deal Type : Private Placement
Lead Product(s) : Izokibep
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Morgan Stanley
Deal Size : $621.0 million
Deal Type : Public Offering
Details : Company will use the proceeds to fund its operations, including the development of pipeline including Izokibep and commercialization activities, business development activities, and capital expenditures.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 09, 2023
Lead Product(s) : Izokibep
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Morgan Stanley
Deal Size : $621.0 million
Deal Type : Public Offering
Lead Product(s) : Izokibep
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Morgan Stanley
Deal Size : $540.0 million
Deal Type : Public Offering
ACELYRIN, INC. Announces Pricing of Upsized Initial Public Offering
Details : The net proceeds will be used to advance the clinical development of izokibep through topline data in Phase 2b/3 trials of izokibep in each of HS, PsA, and uveitis.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 04, 2023
Lead Product(s) : Izokibep
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Morgan Stanley
Deal Size : $540.0 million
Deal Type : Public Offering
Lead Product(s) : B244
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
AOBiome Therapeutics Granted Composition of Matter Patent for its Clinical Candidate B244
Details : B244 platform is a patented, proprietary, topical formulation. Once deployed, B244 produces nitric oxide, a signaling molecule known to regulate inflammation and vasodilation. It has shown clinical significance for atopic dermatitis and associated prurit...
Brand Name : B244
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 06, 2023
Lead Product(s) : B244
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Coacillium
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : LH-8 (coacillium) is an investigational topical botanical drug. Drug interrupts the immuno-inflammatory reactions and their deleterious consequences on hair follicles and adjacent dermal tissues via a pleiotropic mechanism.
Brand Name : LH-8
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 06, 2023
Lead Product(s) : Coacillium
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Adalimumab
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Alliance Global Partners
Deal Size : $6.0 million
Deal Type : Public Offering
Details : Adalimumab is a monoclonal anti-tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, crohn's disease, and ankylosing spondylitis.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
December 23, 2022
Lead Product(s) : Adalimumab
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Alliance Global Partners
Deal Size : $6.0 million
Deal Type : Public Offering
Lead Product(s) : Adalimumab
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Alliance Global Partners
Deal Size : $6.0 million
Deal Type : Public Offering
Details : Research at Oxford University has indicated an anti-TNF mechanism of Adalimumab can slow or prevent the proliferation of myoblast cells that lead to the formation and growth of the fibrous nodules/cords in the palm and possible finger contracture.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
December 20, 2022
Lead Product(s) : Adalimumab
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Alliance Global Partners
Deal Size : $6.0 million
Deal Type : Public Offering
LOOKING FOR A SUPPLIER?