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Find Clinical Drug Pipeline Developments & Deals for Deucravacitinib

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                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Sotyktu (deucravacitinib) is an oral, selective, allosteric TYK2 inhibitor. It inhibits the signaling of IL-23/12 and Type 1 IFN, cytokines involved in the pathogenesis of immune-mediated diseases.

                          Brand Name : Sotyktu

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 27, 2024

                          Lead Product(s) : Deucravacitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase IV

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Sotyktu (deucravacitinib) is an oral, selective, allosteric TYK2 inhibitor with a unique mechanism of action. It inhibits the signaling of IL-23, IL-12 and Type 1 IFN, key cytokines involved in the pathogenesis of moderate-to-severe plaque psoriasis.

                          Brand Name : Sotyktu

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 11, 2023

                          Lead Product(s) : Deucravacitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Sotyktu (deucravacitinib) is an oral, selective, allosteric TYK2 inhibitor with a unique mechanism of action. It inhibits the signaling of IL-23, IL-12 and Type 1 IFN, key cytokines involved in the pathogenesis of multiple immune-mediated diseases.

                          Brand Name : Sotyktu

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 28, 2023

                          Lead Product(s) : Deucravacitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Sotyktu (deucravacitinib) is an oral, selective, allosteric TYK2 inhibitor with a unique mechanism of action. It inhibits the signaling of IL-23, IL-12 and Type 1 IFN, key cytokines involved in the pathogenesis of multiple immune-mediated diseases.

                          Brand Name : Sotyktu

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 27, 2023

                          Lead Product(s) : Deucravacitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Results add to the growing body of evidence and reinforce the efficacy profile of Sotyktu (deucravacitinib), a once-daily, oral, selective, allosteric tyrosine kinase 2 (TYK2) inhibitor for the treatment of moderate-to-severe plaque psoriasis.

                          Brand Name : Sotyktu

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 10, 2022

                          Lead Product(s) : Deucravacitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Approval is based on results from pivotal Phase 3 trials, which demonstrated superior efficacy of once-daily Sotyktu (deucravacitinib) compared to placebo and twice-daily Otezla® (apremilast) in 1,684 patients aged 18 years and older with moderate-to-se...

                          Brand Name : Sotyktu

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 09, 2022

                          Lead Product(s) : Deucravacitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : BMS-986165 (Deucravacitinib), showed statistically significant efficacy at primary endpoint of Systemic Lupus Erythematosus (SLE) Responder Index-4 (SRI(4)) responses versus placebo at Week 32.

                          Brand Name : BMS-986165

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 01, 2022

                          Lead Product(s) : Deucravacitinib

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Results from the POETYK PSO long-term extension (LTE) trial demonstrating durable efficacy and a consistent safety profile with BMS-986165 (deucravacitinib) treatment in adult patients with moderate to severe plaque psoriasis.

                          Brand Name : BMS-986165

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 12, 2022

                          Lead Product(s) : Deucravacitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Applications supported by positive results from the pivotal Phase 3 POETYK-PSO clinical trial program demonstrating superior efficacy of deucravacitinib over Otezla® (apremilast) and placebo in treating adults with moderate to severe plaque psoriasis.

                          Brand Name : BMS-986165

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 29, 2021

                          Lead Product(s) : Deucravacitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Deucravacitinib is a first-in-class, oral, selective tyrosine kinase 2 (TYK2) inhibitor, is being studied in multiple immune-mediated diseases, including psoriasis, psoriatic arthritis, lupus and inflammatory bowel disease.

                          Brand Name : BMS-986165

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 07, 2021

                          Lead Product(s) : Deucravacitinib

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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