Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Study Phase : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bristol Myers Shows Sotyktu Efficacy in Scalp Psoriasis And Real-World Data
Details : Sotyktu (deucravacitinib) is an oral, selective, allosteric TYK2 inhibitor. It inhibits the signaling of IL-23/12 and Type 1 IFN, cytokines involved in the pathogenesis of immune-mediated diseases.
Brand Name : Sotyktu
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 27, 2024
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Highest Development Status : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Sotyktu (deucravacitinib) is an oral, selective, allosteric TYK2 inhibitor with a unique mechanism of action. It inhibits the signaling of IL-23, IL-12 and Type 1 IFN, key cytokines involved in the pathogenesis of moderate-to-severe plaque psoriasis.
Brand Name : Sotyktu
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 11, 2023
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Sotyktu (deucravacitinib) is an oral, selective, allosteric TYK2 inhibitor with a unique mechanism of action. It inhibits the signaling of IL-23, IL-12 and Type 1 IFN, key cytokines involved in the pathogenesis of multiple immune-mediated diseases.
Brand Name : Sotyktu
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 28, 2023
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Sotyktu (deucravacitinib) is an oral, selective, allosteric TYK2 inhibitor with a unique mechanism of action. It inhibits the signaling of IL-23, IL-12 and Type 1 IFN, key cytokines involved in the pathogenesis of multiple immune-mediated diseases.
Brand Name : Sotyktu
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 27, 2023
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Results add to the growing body of evidence and reinforce the efficacy profile of Sotyktu (deucravacitinib), a once-daily, oral, selective, allosteric tyrosine kinase 2 (TYK2) inhibitor for the treatment of moderate-to-severe plaque psoriasis.
Brand Name : Sotyktu
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 10, 2022
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Approval is based on results from pivotal Phase 3 trials, which demonstrated superior efficacy of once-daily Sotyktu (deucravacitinib) compared to placebo and twice-daily Otezla® (apremilast) in 1,684 patients aged 18 years and older with moderate-to-se...
Brand Name : Sotyktu
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 09, 2022
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Deucravacitinib
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BMS-986165 (Deucravacitinib), showed statistically significant efficacy at primary endpoint of Systemic Lupus Erythematosus (SLE) Responder Index-4 (SRI(4)) responses versus placebo at Week 32.
Brand Name : BMS-986165
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 01, 2022
Lead Product(s) : Deucravacitinib
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Results from the POETYK PSO long-term extension (LTE) trial demonstrating durable efficacy and a consistent safety profile with BMS-986165 (deucravacitinib) treatment in adult patients with moderate to severe plaque psoriasis.
Brand Name : BMS-986165
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 12, 2022
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Applications supported by positive results from the pivotal Phase 3 POETYK-PSO clinical trial program demonstrating superior efficacy of deucravacitinib over Otezla® (apremilast) and placebo in treating adults with moderate to severe plaque psoriasis.
Brand Name : BMS-986165
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 29, 2021
Lead Product(s) : Deucravacitinib
Therapeutic Area : Dermatology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Deucravacitinib
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Deucravacitinib is a first-in-class, oral, selective tyrosine kinase 2 (TYK2) inhibitor, is being studied in multiple immune-mediated diseases, including psoriasis, psoriatic arthritis, lupus and inflammatory bowel disease.
Brand Name : BMS-986165
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 07, 2021
Lead Product(s) : Deucravacitinib
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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