Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : $1.2 million
Deal Type : Private Placement
Devonian Announces Closing of a Private Placement of $1.2 Million
Details : The proceeds will fund the preparation of clinical study programs for PUR0110 (thykamine) in phase 2/3 program of pediatric atopic dermatitis, phase 2 programs of radiodermatitis associated with radiotherapy and in Hand and Foot Syndrome and associated w...
Brand Name : PUR0110
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 06, 2023
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : $1.2 million
Deal Type : Private Placement
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : TSX Venture Exchange
Deal Size : $5.0 million
Deal Type : Private Placement
Devonian Announces Private Placement of up to $5 Million
Details : The proceeds will fund the clinical study programs for PUR0110 (thykamine) in particular the phase 2/3 program in pediatric atopic dermatitis, the phase 2 programs in radiodermatitis associated with radiotherapy and in Hand and Foot Syndrome and associat...
Brand Name : PUR0110
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 19, 2023
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : TSX Venture Exchange
Deal Size : $5.0 million
Deal Type : Private Placement
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Thykamine (PUR0110) is a highly innovative product for the prevention and treatment of health conditions related to inflammation and oxidative stress including ulcerative colitis, atopic dermatitis, psoriasis, rheumatoid arthritis, and other autoimmune d...
Brand Name : PUR0110
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 12, 2022
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In the study, a significantly greater proportion of adult patients treated with Thykamine™ (PUR0110) cream 0.10% achieved an IGA of clear/almost clear and at least a 2-grade improvement from baseline in IGA (30.8%) compared to placebo (6.7%; P =.014).
Brand Name : PUR0110
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 06, 2022
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The benefit of PUR0110 (Thykamine) cream 0.10% was supported by a statistically significant effect on the primary and secondary endpoints of Body Surface Area (BSA), pruritis, and Patient-Oriented Eczema Measure score (POEM).
Brand Name : PUR0110
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 26, 2022
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : PurGenesis Technologies
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : According to the results from the study, Thykamine at 0.1% showed significant improvement in skin clearance versus placebo at all measured timelines, thereby meeting the primary endpoint. It showed a fast onset of the therapeutic effect.
Brand Name : PUR0110
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 18, 2021
Lead Product(s) : Thykamine
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : PurGenesis Technologies
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Thylakoid extract
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Devonian announced that the US Patent and Trademark Office has issued a Notice of Allowance for patent titled “Thylakoid Extract Composition and Formulation for the Treatment of Inflammatory Bowel Disease" covering the use of Thykamine™ for the treat...
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 15, 2020
Lead Product(s) : Thylakoid extract
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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