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                            Lead Product(s) : Opevesostat,Dexamethasone,Fludrocortisone Acetate

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                            Deal Type : Licensing Agreement

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                            Merck and Orion Mutual Option Exercise for Opevesostat in Prostate Cancer Treatment

                            Details : Through the license agreement, Merck will gain global rights to develop and commercialize MK-5684 (opevesostat), which is being evaluated for metastatic castration-resistant prostate cancer.

                            Brand Name : MK-5684

                            Molecule Type : Small molecule

                            Upfront Cash : $290.0 million

                            July 01, 2024

                            Lead Product(s) : Opevesostat,Dexamethasone,Fludrocortisone Acetate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Merck & Co

                            Deal Size : $1,920.0 million

                            Deal Type : Licensing Agreement

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                            02

                            Orion Corporation

                            Finland
                            Pharma, Lab & Chemical Expo
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : MK5684,Dexamethasone,Fludrocortisone Acetate

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Orion and MSD Initiate Two Phase 3 Trials Of ODM-208 in Prostate Cancer

                            Details : ODM-208/MK5684, a CYP11A1 inhibitor, is in Phase 3 trials for metastatic castration-resistant prostate cancer with hormone replacement.

                            Brand Name : ODM-208

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 05, 2024

                            Lead Product(s) : MK5684,Dexamethasone,Fludrocortisone Acetate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Sanofi

                            France
                            Pharma, Lab & Chemical Expo
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

                            Lead Product(s) : Isatuximab,Pomalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Press Release: Sarclisa® (isatuximab) Plus KRd Significantly Improved Rate of Minimal Residual Disease Negati...

                            Details : Sarclisa (isatuximab) is a antibody that binds to a specific epitope on the CD38 receptor on multiple myeloma (MM) cells. It is being evaluated in phase 3 clinical trials in combination with carfilzomib, lenalidomide & dexamethasone (KRd) for the treatme...

                            Brand Name : Sarclisa

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            December 11, 2023

                            Lead Product(s) : Isatuximab,Pomalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Orion Corporation

                            Finland
                            Pharma, Lab & Chemical Expo
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : MK-5684,Dexamethasone,Hydrocortisone

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Phase 3 Clinical Trials with ODM-208 (MK-5684) posted to ClinicalTrials.gov Database

                            Details : ODM-208 (or MK-5684) is an investigational oral, non-steroidal and selective inhibitor of the CYP11A1 enzyme discovered and developed by Orion for the treatment of hormone-dependent cancers, such as metastatic castration-resistant prostate cancer.

                            Brand Name : ODM-208

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 21, 2023

                            Lead Product(s) : MK-5684,Dexamethasone,Hydrocortisone

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            AbbVie Inc

                            U.S.A
                            Pharma, Lab & Chemical Expo
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Dexamethasone

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            NICE Recommendation Expands Patient Eligibility for AbbVie’s Ozurdex (dexamethasone 0.7mg intravitreal impla...

                            Details : NICE recommends Ozurdex® (dexamethasone) as an option for treating visual impairment caused by DMO in adults, only when it has not responded well enough to, or they cannot have non-corticosteroid therapy.

                            Brand Name : Ozurdex

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 11, 2022

                            Lead Product(s) : Dexamethasone

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Sanofi

                            France
                            Pharma, Lab & Chemical Expo
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

                            Lead Product(s) : Isatuximab-irfc,Pomalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Sarclisa® (Isatuximab) Combination Provides Unprecedented Median Progression Free Survival in Patients With R...

                            Details : Latest results from Phase 3 IKEMA clinical trial for Sarclisa®(isatuximab-irfc) in combination with carfilzomib and dexamethasone demonstrated a median PFS of 35.7 months, compared to 19.2 months in patients treated with Kd alone.

                            Brand Name : Sarclisa

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            May 15, 2022

                            Lead Product(s) : Isatuximab-irfc,Pomalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Sanofi

                            France
                            Pharma, Lab & Chemical Expo
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

                            Lead Product(s) : Isatuximab,Pomalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Blackstone Life Sciences

                            Deal Size : $330.0 million

                            Deal Type : Collaboration

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                            Sanofi Announces €300 Million Collaboration with Blackstone Life Sciences to Advance an Innovative Treatment...

                            Details : For the Sarclisa® subcutaneous formulation delivery, Sanofi has partnered with drug delivery technology innovator company to advance the development of a subcutaneous delivery for Sarclisa® with the goal of offering a unique patient-centric treatment e...

                            Brand Name : Sarclisa

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            March 15, 2022

                            Lead Product(s) : Isatuximab,Pomalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Blackstone Life Sciences

                            Deal Size : $330.0 million

                            Deal Type : Collaboration

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                            08

                            Sanofi

                            France
                            Pharma, Lab & Chemical Expo
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

                            Lead Product(s) : Isatuximab-irfc,Pomalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            New SARCLISA® (Isatuximab for Injection) Combination Now Approved by Health Canada for Adults with Relapsed a...

                            Details : SARCLISA® continues to be evaluated in multiple ongoing Phase 3 clinical trials in combination with current standard treatments across the MM treatment continuum. It is also under investigation for the treatment of other hematologic malignancies and sol...

                            Brand Name : Sarclisa

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 13, 2021

                            Lead Product(s) : Isatuximab-irfc,Pomalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Dr. Reddy's Laboratories

                            India
                            Pharma, Lab & Chemical Expo
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

                            Lead Product(s) : Lenalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Dr Reddy’s Labs Launches Generic Revlimid Capsules in Canada

                            Details : Reddy-Lenalidomide capsules are available in 2.5 mg, 5 mg, 10 mg, 15 mg, 20 mg, and 25 mg strengths, each in blister packs.

                            Brand Name : Revlimid

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 02, 2021

                            Lead Product(s) : Lenalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Breckenridge Pharmaceutical

                            U.S.A
                            Pharma, Lab & Chemical Expo
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Carfilzomib,Lenalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Breckenridge Announces Approval of its ANDA for Carfilzomib Intravenous Powder (generic for Kyprolis®)

                            Details : Kyprolis-Generic (carfilzomib) is a proteasome inhibitor, small molecule drug candidate, which is indicated for the treatment of patients with relapsed or refractory multiple myeloma as monotherapy or in combination with dexamethasone or with lenalidomid...

                            Brand Name : Kyprolis-Generic

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            June 16, 2021

                            Lead Product(s) : Carfilzomib,Lenalidomide,Dexamethasone

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            Breckenridge Pharmaceutical

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