Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Denali Capital Acquisition Corp
Deal Size : Undisclosed
Deal Type : Merger
Semnur to go Public via SPAC Merger with Denali Capital in $2.5 bln Deal
Details : Semnur’s lead program, Semdexa (dexamethasone sodium phosphate), is the first non-opioid novel injectable corticosteroid gel formulation for moderate to severe chronic radicular sciatica.
Brand Name : Semdexa
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 03, 2024
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Denali Capital Acquisition Corp
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Quince Announces First Patient Dosed in Phase 3 Trial of EryDex for Ataxia-Telangiectasia
Details : EryDex (dexamethasone sodium phosphate) is a glucocorticoid receptor agonist, which is being evaluated in the late-stage clinical trial studies for the treatment of Ataxia-Telangiectasia.
Brand Name : EryDex
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 25, 2024
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Quince Therapeutics Receives U.S. FDA Fast Track Designation for EryDex System
Details : EryDex (dexamethasone sodium phosphate), utilizing company's AIDE technology, is in Phase 3 for treating Ataxia-Telangiectasia, a rare pediatric condition.
Brand Name : EryDex
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 03, 2024
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Musculoskeletal
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SP-102 (semdexatm) is expected to be administered in up to 3 injections during a 6-month observation period. Completion of enrollment for Lumbosacral Radicular Pain (Sciatica) in the trial is projected to occur in 2025.
Brand Name : SP-102
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 02, 2023
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Quince Therapeutics
Deal Size : $485.0 million
Deal Type : Acquisition
Quince Therapeutics Completes Acquisition of EryDel S.p.A.
Details : Through the acquisition, Quince gains right for EryDel's Phase 3 lead asset, EryDex (dexamethasone sodium phosphate), targeting a rare fatal pediatric neurological disease, Ataxia-Telangiectasia (A-T), which currently has no approved treatments.
Brand Name : EryDex
Molecule Type : Small molecule
Upfront Cash : $485.0 million
October 23, 2023
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Quince Therapeutics
Deal Size : $485.0 million
Deal Type : Acquisition
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EryDex (dexamethasone sodium phosphate) utilizes a unique drug/device combination that enables a fully automated process at the point of patient care for the autologous intracellular drug encapsulation for the Treatment of Ataxia-Telangiectasia.
Brand Name : EryDex
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 28, 2023
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AVM0703 is small molecule immunomodulatory drug enrolling Phase 2 trials in US in relapsed/refractory Non-Hodgkin's Lymphoma (NHL) which began enrollment Q3 2023 (partially funded by NCI Ph II FastTrak grant 1R44CA272096).
Brand Name : AVM0703
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 01, 2023
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Quince Therapeutics
Deal Size : $485.0 million
Deal Type : Acquisition
Details : Through the acquisition, Quince gains right for EryDel's Phase 3 lead asset, EryDex (dexamethasone sodium phosphate), targeting a rare fatal pediatric neurological disease, Ataxia-Telangiectasia (A-T), which currently has no approved treatments.
Brand Name : EryDex
Molecule Type : Small molecule
Upfront Cash : $485.0 million
July 24, 2023
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Quince Therapeutics
Deal Size : $485.0 million
Deal Type : Acquisition
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : National Cancer Institute
Deal Size : $2.0 million
Deal Type : Funding
Details : AVM0703 (Dexamethasone sodium phosphate) is a small molecule which triggers the production and release of endogenous bispecific gamma delta TCR+ invariant TCR+ Natural Killer T-like cells (AVM-NKT).
Brand Name : AVM0703
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 14, 2022
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : National Cancer Institute
Deal Size : $2.0 million
Deal Type : Funding
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Rheumatology
Study Phase : Phase III
Sponsor : Endo International
Deal Size : $140.0 million
Deal Type : Agreement
Details : Under the terms of the agreement, TLC will primarily be responsible for the development of the product TLC599 (Dexamethasone Sodium Phosphate) and EVL will primarily be responsible for obtaining regulatory approval and commercialization of the product in...
Brand Name : TLC599
Molecule Type : Small molecule
Upfront Cash : $30.0 million
June 13, 2022
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Rheumatology
Highest Development Status : Phase III
Sponsor : Endo International
Deal Size : $140.0 million
Deal Type : Agreement
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