Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Df1001,Sacituzumab Govitecan
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Gilead Sciences
Deal Size : Undisclosed
Deal Type : Collaboration
Dragonfly Explores DF1001 with Gilead's Trodelvy® in Cancer Combinations
Details : The collaboration aims to combine DF1001, targeting NK cells and T-cell activation, with Gilead's Trop-2 antibody-drug conjugate for treating breast and lung cancers.
Brand Name : DF1001
Molecule Type : Large molecule
Upfront Cash : Undisclosed
February 15, 2024
Lead Product(s) : Df1001,Sacituzumab Govitecan
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Gilead Sciences
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Df1001,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Dragonfly Therapeutics Announces First Patient Dosed in Phase 1 Study of its EGFR-targeting TriNKET®
Details : The Company’s first TriNKET, DF1001, entered Phase 2 trials this month after being well-tolerated in Phase 1 with encouraging clinical responses, including showing tumor burden reductions across several tumor types, including in HER2-low and heavily pr...
Brand Name : DF1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 08, 2022
Lead Product(s) : Df1001,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Df1001,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : DF1001 was well-tolerated with no dose limiting toxicities during dose escalation in the Phase 1 study. The study showed encouraging pharmacodynamic effects including infiltration of NK cells and T cells into tumors.
Brand Name : DF1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 06, 2022
Lead Product(s) : Df1001,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Df1001,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : DF1001 has potential to stimulate anti-tumor immunity in patients who are not eligible for, or not responding to, current therapies. DF1001 is an investigational candidate that targets natural killer cells and T-cell activation signals to specific recept...
Brand Name : DF1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 09, 2021
Lead Product(s) : Df1001,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Df1001,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : AbbVie Inc
Deal Size : Undisclosed
Deal Type : Collaboration
Dragonfly Therapeutics Announces AbbVie Opt-In of TriNKET™ Immunotherapy Drug Candidate
Details : The opt-in grants AbbVie exclusive worldwide intellectual property rights to develop and commercialize products directed to this first specific target, developed using Dragonfly's TriNKET™ technology platform.
Brand Name : DF1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
January 12, 2021
Lead Product(s) : Df1001,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : AbbVie Inc
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Df1001,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Details : Merck has exercised its option to license exclusive worldwide intellectual property rights on its first immunotherapy candidate developed using the TriNKET™ technology platform and Dragonfly has received an undisclosed payment associated with this mile...
Brand Name : DF1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 01, 2020
Lead Product(s) : Df1001,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
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