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    [{"orgOrder":0,"company":"Dianthus Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"DNTH103","moa":"","graph1":"Immunology","graph2":"Phase I","graph3":"Dianthus Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Dianthus Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Dianthus Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Dianthus Therapeutics","sponsor":"Magenta Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Large molecule","year":"2023","type":"Merger","leadProduct":"DNTH103","moa":"","graph1":"Immunology","graph2":"Phase I","graph3":"Dianthus Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Dianthus Therapeutics \/ Dianthus Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Dianthus Therapeutics \/ Dianthus Therapeutics"},{"orgOrder":0,"company":"Dianthus Therapeutics","sponsor":"Fidelity Management & Research","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Large molecule","year":"2023","type":"Private Placement","leadProduct":"DNTH103","moa":"","graph1":"Immunology","graph2":"Phase II","graph3":"Dianthus Therapeutics","amount2":0.070000000000000007,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0.070000000000000007,"dosageForm":"Injectable\/Injection","sponsorNew":"Dianthus Therapeutics \/ Fidelity Management & Research","highestDevelopmentStatusID":"8","companyTruncated":"Dianthus Therapeutics \/ Fidelity Management & Research"},{"orgOrder":0,"company":"Dianthus Therapeutics","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Private Placement","leadProduct":"DNTH103","moa":"","graph1":"Immunology","graph2":"Phase II","graph3":"Dianthus Therapeutics","amount2":0.23000000000000001,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0.23000000000000001,"dosageForm":"Injection","sponsorNew":"Dianthus Therapeutics \/ Jefferies","highestDevelopmentStatusID":"8","companyTruncated":"Dianthus Therapeutics \/ Jefferies"},{"orgOrder":0,"company":"Dianthus Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"DNTH103","moa":"","graph1":"Immunology","graph2":"Phase II","graph3":"Dianthus Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Dianthus Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Dianthus Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Dianthus Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"DNTH103","moa":"","graph1":"Neurology","graph2":"Phase I","graph3":"Dianthus Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Dianthus Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Dianthus Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Dianthus Therapeutics","sponsor":"Hesperos","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"DNTH103","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Dianthus Therapeutics","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Dianthus Therapeutics \/ Hesperos","highestDevelopmentStatusID":"12","companyTruncated":"Dianthus Therapeutics \/ Hesperos"}]

    Find Clinical Drug Pipeline Developments & Deals by Dianthus Therapeutics

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                            01

                            Dianthus Therapeutics

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                            BIO Partnering at JPM
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                            Dianthus Therapeutics

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                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Hesperos

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Hesperos Supports Investigational Product for Phase II Trial with Human-on-a-Chip®

                            Details : DNTH103 is an investigational, potent mAb engineered to selectively targets by inhibiting only the active form of the C1s protein. It is being evaluated for generalized myasthenia gravis.

                            Brand Name : DNTH103

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 24, 2024

                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Hesperos

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Dianthus Therapeutics

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                            BIO Partnering at JPM
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                            Dianthus Therapeutics

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                            BIO Partnering at JPM
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                            Lead Product(s) : DNTH103

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Dianthus Therapeutics Gets FDA Clearance for Phase 2 Trial of DNTH103 in MMN

                            Details : DNTH103 is a potent monoclonal antibody engineered to selectively inhibitis only the active form of the C1s protein. It is being evaluated for the treatment of Multifocal Motor Neuropathy.

                            Brand Name : DNTH103

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 12, 2024

                            Lead Product(s) : DNTH103

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Dianthus Therapeutics

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                            BIO Partnering at JPM
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                            Dianthus Therapeutics

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                            BIO Partnering at JPM
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                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Dianthus Initiates Phase 2 MaGic Trial Of DNTH103 in Myasthenia Gravis

                            Details : DNTH103 is an investigational, clinical-stage monoclonal antibody targeting the classical pathway by inhibiting the active form of C1s protein, evaluated for generalized myasthenia gravis.

                            Brand Name : DNTH103

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            February 26, 2024

                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Dianthus Therapeutics

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                            BIO Partnering at JPM
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                            Dianthus Therapeutics

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                            BIO Partnering at JPM
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                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Jefferies

                            Deal Size : $230.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Dianthus Therapeutics Announces $230 Million Private Placement

                            Details : The net proceeds will be used for the clinical development of DNTH103. It is a selective inhibitor of the active C1s protein for the treatment of neuromuscular & autoimmune disorders.

                            Brand Name : DNTH103

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            January 22, 2024

                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Jefferies

                            Deal Size : $230.0 million

                            Deal Type : Private Placement

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                            05

                            Dianthus Therapeutics

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                            BIO Partnering at JPM
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                            Dianthus Therapeutics

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                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Recipient : Magenta Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Magenta Therapeutics and Dianthus Therapeutics Announce Merger Agreement

                            Details : The combined company will focus on advancing Dianthus’ pipeline of next-generation complement inhibitors, including DNTH103, an investigational long-acting classical complement pathway inhibitor, currently in a Phase 1 trial to treat people with severe...

                            Brand Name : DNTH103

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            May 03, 2023

                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Recipient : Magenta Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            06

                            Dianthus Therapeutics

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                            BIO Partnering at JPM
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                            Dianthus Therapeutics

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                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Fidelity Management & Research

                            Deal Size : $70.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Magenta Therapeutics and Dianthus Therapeutics Announce Merger Agreement

                            Details : The net financing will be used to fund DNTH103 through multiple clinical data catalysts including Phase 1 in healthy volunteers, and Phase 2 trials in generalized Myasthenia Gravis and other indications.

                            Brand Name : DNTH103

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            May 03, 2023

                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Fidelity Management & Research

                            Deal Size : $70.0 million

                            Deal Type : Private Placement

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                            07

                            Dianthus Therapeutics

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                            Dianthus Therapeutics

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                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Dianthus Therapeutics Announces First Participant Dosed in Phase 1 Trial of DNTH103, a Selective Inhibitor of ...

                            Details : DNTH103 is a next-generation monoclonal antibody that selectively targets only the active form of the C1s protein in the classical complement pathway. DNTH103 is designed as an infrequent and convenient subcutaneous injection.

                            Brand Name : DNTH103

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 30, 2022

                            Lead Product(s) : DNTH103

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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