Lead Product(s) : Dipraglurant
Therapeutic Area : Neurology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Following oral administration, ADX48621 (dipraglurant) was rapidly absorbed and readily crossed the blood-brain barrier. In vivo, dipraglurant administration was found to dose-dependently impact the various NMS disease models.
Brand Name : ADX48621
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 04, 2023
Lead Product(s) : Dipraglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dipraglurant
Therapeutic Area : Neurology
Study Phase : Phase II/ Phase III
Sponsor : Armistice Master Fund Ltd.
Deal Size : $4.2 million
Deal Type : Financing
Addex Completes $4.2 Million Equity Financing
Details : Addex intends to use the net proceeds from this offering to advance its clinical and preclinical pipeline including development and commercialization of its lead asset ADX48621(dipraglurant).
Brand Name : ADX48621
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 26, 2022
Lead Product(s) : Dipraglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II/ Phase III
Sponsor : Armistice Master Fund Ltd.
Deal Size : $4.2 million
Deal Type : Financing
Lead Product(s) : Dipraglurant
Therapeutic Area : Neurology
Study Phase : Phase II/ Phase III
Sponsor : Armistice Master Fund LTV
Deal Size : $4.2 million
Deal Type : Financing
Addex Raises $4.2 Million in Equity Financing
Details : Addex intends to use the net proceeds from this offering to advance its clinical and preclinical pipeline including development and commercialization of its lead asset ADX48621(dipraglurant).
Brand Name : ADX48621
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 22, 2022
Lead Product(s) : Dipraglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II/ Phase III
Sponsor : Armistice Master Fund LTV
Deal Size : $4.2 million
Deal Type : Financing
Lead Product(s) : Dipraglurant
Therapeutic Area : Neurology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ADX48621 (Dipraglurant (Immediate Release), as a novel orally available mGlu5 NAM, for the treatment of levodopa-induced dyskinesia associated with Parkinson’s disease (PD-LID).
Brand Name : ADX48621
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 17, 2022
Lead Product(s) : Dipraglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dipraglurant
Therapeutic Area : Ophthalmology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Addex Provides Update on Dipraglurant Blepharospasm Phase 2 Feasibility Clinical Study
Details : ADX48621 (dipraglurant), is a metabotropic glutamate receptor subtype 5 negative allosteric modulator, or mGlu5 NAM. It’s lead indication is levodopa induced dyskinesia associated with Parkinson’s disease, or PD-LID.
Brand Name : ADX48621
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 27, 2022
Lead Product(s) : Dipraglurant
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dipraglurant
Therapeutic Area : Ophthalmology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Addex Therapeutics Initiates Phase 2 Clinical Study with Dipraglurant in Blepharospasm
Details : The double-blind, randomized Phase 2a feasibility study will enroll 15 patients with blepharospasm. It is designed to assess the safety and tolerability of dipraglurant as well as explore its effects on the severity and frequency of blepharospasm signs a...
Brand Name : ADX48621
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 29, 2021
Lead Product(s) : Dipraglurant
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dipraglurant
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $11.5 million
Deal Type : Public Offering
Addex Successfully Completes $11.5 Million Capital Increase
Details : Addex intends to use the net proceeds from the global offering, mainly to advance development of its portfolio of proprietary drug candidates based on its allosteric modulator development capabilities. These include dipraglurant for use in Parkinson's di...
Brand Name : ADX48621
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 11, 2021
Lead Product(s) : Dipraglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : H.C. Wainwright & Co
Deal Size : $11.5 million
Deal Type : Public Offering
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