Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Study Phase : Approved
Recipient : EffRx Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Efmody® is a modified-release preparation of hydrocortisone that has been specifically designed for the treatment of patients with CAH, a rare condition caused by a genetic deficiency of adrenal enzymes.
Brand Name : Efmody
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 26, 2022
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Recipient : EffRx Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Efmody® is a preparation of hydrocortisone that has been specifically designed for patients with CAH, a rare condition caused by deficiency of adrenal enzymes, most commonly 21-hydroxylase.
Brand Name : Efmody
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 13, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Study Phase : Approved
Sponsor : Citrine Medicine
Deal Size : $2.2 million
Deal Type : Partnership
Diurnal Triggers $1.25m in Milestone Payments from Citrine Medicine
Details : The $1.25 million milestone payment has been triggered as a result of the recent European Commission’s approval for Efmody® (hydrocortisone modified-release hard capsules) and the attainment by Citrine of certain development milestones in China for A...
Brand Name : Efmody
Molecule Type : Small molecule
Upfront Cash : $1.0 million
June 01, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Sponsor : Citrine Medicine
Deal Size : $2.2 million
Deal Type : Partnership
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Diurnal Group plc - Diurnal receives European Commission approval for Efmody®
Details : Efmody® is a preparation of hydrocortisone that has been specifically designed for patients with CAH, an orphan condition caused by deficiency of adrenal enzymes, most commonly 21-hydroxylase.
Brand Name : Efmody
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 28, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Diurnal Group plc - Chronocort® Phase 3 and Safety Extension Study Results Published in JCEM
Details : The Phase 3 study results published by the JCEM found that although the standard-deviation-score-focused primary endpoint of the study was missed, Chronocort® improved morning and early afternoon biochemical control for adults with CAH over standard glu...
Brand Name : Chronocort
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 02, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Study Phase : Approved
Sponsor : Citrine
Deal Size : $13.2 million
Deal Type : Licensing Agreement
Details : Citrine will be responsible for obtaining registration for Alkindi® as a treatment for paediatric patients in China and for all commercialisation activities, including pricing and reimbursement.
Brand Name : Alkindi
Molecule Type : Small molecule
Upfront Cash : $0.5 million
January 27, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Sponsor : Citrine
Deal Size : $13.2 million
Deal Type : Licensing Agreement
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Study Phase : Approved
Sponsor : Eton Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Acquisition
Eton Pharmaceuticals Announces Acquisition of Canadian Rights for ALKINDI® SPRINKLE
Details : Eton Pharmaceuticals Canadian rights to ALKINDI® SPRINKLE from Diurnal Group plc. Eton Pharmaceuticals currently commercializes ALKINDI® SPRINKLE in the United States as a replacement therapy for Adrenocortical Insufficiency (AI) in children under 17 y...
Brand Name : Alkindi Sprinkle
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 14, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Sponsor : Eton Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The submission for the MHRA is based on the data from the Company’s Phase 3 study, an open-label safety extension study of Chronocort® and written formal Scientific Advice received in April 2019 confirming the clinical and regulatory pathway for Chron...
Brand Name : Chronocort
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 12, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Study Phase : Approved
Sponsor : EffRx
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the terms of the agreement EffRx has received the exclusive rights to register and commercialize Alkindi® in Switzerland.
Brand Name : Alkindi Sprinkle
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 21, 2020
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Sponsor : EffRx
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Eton Pharmaceuticals
Deal Size : $7.5 million
Deal Type : Licensing Agreement
Details : The acquisition advanced Eton’s leadership in pediatric rare diseases products providing a $100 million market opportunity.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : $3.5 million
March 27, 2020
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Eton Pharmaceuticals
Deal Size : $7.5 million
Deal Type : Licensing Agreement
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