11
ALL5
Corium1
Eisai1
ICURE PHARM, INC1
KemPharm1
NeuroSense Therapeutics1
Suven Life Sciences Limited1
TheranexusYear
11
ALL4
20234
20222
20211
2020DEALS // DEV.
11
ALL2
Deals9
DevelopmentsCountry
11
ALL1
FRANCE1
INDIA1
ISRAEL1
JAPAN1
SOUTH KOREA6
U.S.A11
ALL1
Corium9
Inapplicable1
Lotus PharmaceuticalTherapeutic Area
11
ALL11
NeurologyStudy Phase
11
ALL8
Approved FDF2
Phase II1
Phase IDeal Type
11
ALL1
Agreement9
Inapplicable1
Licensing AgreementProduct Type
11
ALL11
Other Small MoleculeDosage Form
11
ALL1
Oral1
Oral Capsule1
Oral Suspension1
Oral Tablet7
Transdermal PatchLead Product
11
ALL10
Donepezil1
MasupirdineTarget
11
ALL1
5-HT6 receptor10
AChELead Product(s) : Donepezil
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ADLARITY (donepezil transdermal system) developed by Corium, is the first and only U.S. FDA approved once-weekly, donepezil transdermal system for patients with mild, moderate and severe dementia of the Alzheimer's type.
Product Name : Adlarity
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 09, 2023
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Masupirdine,Donepezil
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Suven Life Sciences Breathes New Life Into Drug Discovery Plans
Details : SUVN-502 (masupirdine) is a novel, potent, pure, and orally active 5-HT6 receptor antagonist, it is being investigated as a potential therapy against alzheimer's disease.
Product Name : SUVN-502
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 03, 2023
Lead Product(s) : Masupirdine,Donepezil
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Lotus Pharmaceutical
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, Lotus will have exclusive rights to commercialize Adlarity (donepezil transdermal system), an innovative Alzheimer’s dementia treatment, in the applicable territory and will be responsible for the regulatory approval p...
Product Name : Adlarity
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
October 08, 2023
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Lotus Pharmaceutical
Deal Size : Undisclosed
Deal Type : Licensing Agreement
NeuroSense Therapeutics Reports Positive Final Results from Alzheimer's Biomarker Study
Details : Cognic (donepezil) is a transactive response DNA binding protein of 43 kDa (TDP-43) is involved in regulation of gene expression. AD patients with TDP-43 pathology have increased severity of cognitive impairment compared to those without TDP-43 pathology...
Product Name : Cognic
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 19, 2023
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The results of Study 419 did not show statistically significant difference in efficacy between placebo and Aricept (donepezil hydrochloride) groups at time of final analysis in primary endpoint, CIBIC-plus comprehensive assessment.
Product Name : Aricept
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 29, 2022
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ADLARITY is the first and only once-weekly patch to continuously deliver consistent doses of donepezil through the skin. Donepezil is the most prescribed medication in a class of Alzheimer's drugs known as acetylcholinesterase inhibitors.
Product Name : Adlarity
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 19, 2022
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Corium
Deal Size : $2.0 million
Deal Type : Agreement
Details : KemPharm is due to receive the fee, within 30 days following FDA approval of ADLARITY, pursuant to a master development services agreement entered into with Corium in July 2020, under which KemPharm provided development related to Corium’s resubmission...
Product Name : Adlarity
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 16, 2022
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Corium
Deal Size : $2.0 million
Deal Type : Agreement
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The approval of ADLARITY (donepezil transdermal system) reinforces the value of Corium's innovative CORPLEX technology, our CNS expertise, and our mission to deliver solutions that transform care for the Alzheimer's community and others impacted by CNS d...
Product Name : Adlarity
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 14, 2022
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The ADLARITY transdermal patch is constructed to be worn for seven days with consistent adhesion, a delivery method that avoids the difficulties associated with daily delivery of an oral medication for patients with significant memory problems.
Product Name : Adlarity
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 10, 2021
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Donepezil is a current typical treatment that has been widely prescribed for the longest period for Alzheimer’s disease patients in severity ranging from mild to moderate and severe ones among FDA-approved Alzheimer's treatments.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 16, 2021
Lead Product(s) : Donepezil
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable