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    [{"orgOrder":0,"company":"DTx Pharma","sponsor":"Alzheimer's Association","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Cell and Gene therapy","year":"2020","type":"Funding","leadProduct":"siRNAs","moa":"MSUT2 gene","graph1":"Neurology","graph2":"Preclinical","graph3":"DTx Pharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"DTx Pharma \/ Alzheimer's Association","highestDevelopmentStatusID":"4","companyTruncated":"DTx Pharma \/ Alzheimer's Association"},{"orgOrder":0,"company":"DTx Pharma","sponsor":"RA Capital Management","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"","productType":"Large molecule","year":"2021","type":"Series B Financing","leadProduct":"RNA-based therapeutics","moa":"","graph1":"Genetic Disease","graph2":"IND Enabling","graph3":"DTx Pharma","amount2":0.10000000000000001,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Genetic Disease","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"DTx Pharma \/ RA Capital Management","highestDevelopmentStatusID":"5","companyTruncated":"DTx Pharma \/ RA Capital Management"},{"orgOrder":0,"company":"DTx Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"DTx-1252","moa":"","graph1":"Genetic Disease","graph2":"IND Enabling","graph3":"DTx Pharma","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"","sponsorNew":"DTx Pharma \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"DTx Pharma \/ Not Applicable"},{"orgOrder":0,"company":"DTx Pharma","sponsor":"Novartis Pharmaceuticals Corporation","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"","productType":"Large molecule","year":"2023","type":"Acquisition","leadProduct":"DTx-1252","moa":"","graph1":"Genetic Disease","graph2":"IND Enabling","graph3":"DTx Pharma","amount2":1,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Genetic Disease","amount2New":1,"dosageForm":"","sponsorNew":"DTx Pharma \/ Novartis Pharmaceuticals Corporation","highestDevelopmentStatusID":"5","companyTruncated":"DTx Pharma \/ Novartis Pharmaceuticals Corporation"}]

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                            DTx Pharma

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                            Lead Product(s) : DTx-1252

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $1,000.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            DTx Pharma Announces Acquisition by Novartis

                            Details : Through the acquisition, Novartis will accelerate the development of DTx-1252, a novel, potential first-in-class, FALCON siRNA candidate targeting PMP22, for the treatment of Charcot-Marie-Tooth Disease Type 1A (CMT1A).

                            Brand Name : DTx-1252

                            Molecule Type : Large molecule

                            Upfront Cash : $500.0 million

                            July 17, 2023

                            Lead Product(s) : DTx-1252

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $1,000.0 million

                            Deal Type : Acquisition

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                            Lead Product(s) : DTx-1252

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            DTx Pharma Receives FDA Orphan Drug Designation for DTx-1252 for the Treatment of Charcot-Marie-Tooth Disease ...

                            Details : DTx-1252 is a potential first-in-class FALCON™ siRNA therapeutic for treatment of CMT1A. By repressing PMP22, DTx-1252 reverses CMT1A in a mouse model that faithfully recapitulates the genetic and clinical manifestations of the disease.

                            Brand Name : DTx-1252

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 07, 2023

                            Lead Product(s) : DTx-1252

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : RNA-based therapeutics

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : RA Capital Management

                            Deal Size : $100.0 million

                            Deal Type : Series B Financing

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                            DTx Pharma Completes $100M Series B Financing to Advance its FALCON™ Platform and Pipeline of RNA Therapeuti...

                            Details : Proceeds from the financing will be used to advance DTx’s pipeline utilizing its novel FALCON (Fatty Acid Ligand Conjugated OligoNucleotide) platform technology.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            March 01, 2021

                            Lead Product(s) : RNA-based therapeutics

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : RA Capital Management

                            Deal Size : $100.0 million

                            Deal Type : Series B Financing

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                            Lead Product(s) : siRNAs

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Alzheimer's Association

                            Deal Size : $0.4 million

                            Deal Type : Funding

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                            DTx Pharma Receives Prestigious Funding Award to Support Research in Neurodegenerative Diseases of the CNS

                            Details : The award, along with prior and pending grants, will enable DTx to expand the application of its lipid conjugate technology for the delivery of oligonucleotides as potential treatment for neurodegenerative diseases.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            May 13, 2020

                            Lead Product(s) : siRNAs

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Alzheimer's Association

                            Deal Size : $0.4 million

                            Deal Type : Funding

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