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Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Lisata Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"AstraZeneca","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Durvalumab","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"AstraZeneca","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"AstraZeneca \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"AstraZeneca \/ Not Applicable"},{"orgOrder":0,"company":"AstraZeneca","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Durvalumab","moa":"","graph1":"Technology","graph2":"Phase 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Find Clinical Drug Pipeline Developments & Deals for Durvalumab

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Imjudo (tremelimumab) is a CTLA4 Inhibitor antibody, which is indicated in combination with durvalumab for the treatment of patients with unresectable hepatocellular carcinoma.

                          Brand Name : Imjudo

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 23, 2024

                          Lead Product(s) : Tremelimumab,Durvalumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : AIM’s Ampligen (rintatolimod) is being evaluated in combination with AstraZeneca’s anti-PD-L1 immune checkpoint inhibitor Imfinzi (durvalumab) in treating late-stage pancreatic cancer.

                          Brand Name : Ampligen

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 19, 2024

                          Lead Product(s) : Rintatolimod,Durvalumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : AstraZeneca

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : LSTA1 (certepetide) is an integrin alpha-V antagonist which is being evaluated in combination with durvalumab & chemotherapy for the treatment of second-line cholangiocarcinoma.

                          Brand Name : LSTA1

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          September 17, 2024

                          Lead Product(s) : Certepetide,Durvalumab,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Imfinzi (durvalumab) is a PD-L1 Inhibitor antibody, which is currently being evaluated in combination with tremelimumab for unresectable small cell lung cancer.

                          Brand Name : Imfinzi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 16, 2024

                          Lead Product(s) : Durvalumab,Tremelimumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Imfinzi (durvalumab) is an anti-PD-L1 human monoclonal antibody. It is being evaluated for the treatment of patients with muscle-invasive bladder cancer with cisplatin, gemcitabine.

                          Brand Name : Imfinzi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 15, 2024

                          Lead Product(s) : Durvalumab,Cisplatin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : LSTA1 (certepetide) is an integrin alpha-V antagonist which is being evaluated in combination with durvalumab & chemotherapy for the treatment of cholangiocarcinoma.

                          Brand Name : LSTA1

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          September 05, 2024

                          Lead Product(s) : Certepetide,Durvalumab,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Imfinzi (durvalumab) is an anti-PD-L1 human monoclonal antibody. It is being evaluated for the treatment of resectable early-stage (IIA-IIIB) non-small cell lung cancer in adults.

                          Brand Name : Imfinzi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 16, 2024

                          Lead Product(s) : Durvalumab,Carboplatin,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Imfinzi (durvalumab, PD-L1 inhibitor) in combination with chemotherapy has been approved in US for the treatment of adult patients with resectable early-stage (IIA-IIIB) non-small cell lung cancer.

                          Brand Name : Imfinzi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 16, 2024

                          Lead Product(s) : Durvalumab,Cisplatin,Carboplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Imfinzi (durvalumab) is an anti-PD-L1 human monoclonal antibody. It is being evaluated for the treatment of patients with limited-stage small cell lung cancer.

                          Brand Name : Imfinzi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 15, 2024

                          Lead Product(s) : Durvalumab,Tremelimumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : LSTA1 (certepetide) is an integrin alpha-V antagonist which is being evaluated in combination with durvalumab & chemotherapy for the treatment of cholangiocarcinoma.

                          Brand Name : LSTA1

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          July 16, 2024

                          Lead Product(s) : Certepetide,Durvalumab,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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