Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AAV-based Therapy
Therapeutic Area : Neurology
Study Phase : Discovery Platform
Sponsor : F. Hoffmann-La Roche
Deal Size : $1,050.0 million
Deal Type : Collaboration
Roche Bets Up to $1B to Expand Dyno Gene Therapy Delivery Pact
Details : The collaboartion aims to develop next-generation adeno-associated virus (AAV) vectors for gene therapies targeting neurological diseases.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : $50.0 million
October 24, 2024
Lead Product(s) : AAV-based Therapy
Therapeutic Area : Neurology
Highest Development Status : Discovery Platform
Sponsor : F. Hoffmann-La Roche
Deal Size : $1,050.0 million
Deal Type : Collaboration
Lead Product(s) : AAV Capsids
Therapeutic Area : Genetic Disease
Study Phase : Discovery
Sponsor : Astellas Pharma
Deal Size : $1,618.0 million
Deal Type : Collaboration
Details : Under the terms of agreement, Dyno will design novel AAV capsids with improved functional properties for gene therapy, while Astellas will be responsible for conducting preclinical, clinical and commercialization activities, of gene therapy candidates us...
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : $18.0 million
December 02, 2021
Lead Product(s) : AAV Capsids
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery
Sponsor : Astellas Pharma
Deal Size : $1,618.0 million
Deal Type : Collaboration
Lead Product(s) : AAV based-gene therapy
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Discovery Platform
Sponsor : Andreessen Horowitz
Deal Size : $100.0 million
Deal Type : Series A Financing
Details : Funds from this financing will directly fund expansion of the company’s CapsidMap™ platform, which uses AI technology for the design of novel Adeno-Associated Virus (AAV) gene therapy vectors.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
May 06, 2021
Lead Product(s) : AAV based-gene therapy
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Discovery Platform
Sponsor : Andreessen Horowitz
Deal Size : $100.0 million
Deal Type : Series A Financing
Lead Product(s) : AAV vectors based gene therapies
Therapeutic Area : Neurology
Study Phase : Discovery Platform
Sponsor : F. Hoffmann-La Roche
Deal Size : $1,800.0 million
Deal Type : Collaboration
Details : Dyno will design novel AAV capsids with improved functional properties for gene therapy, while Roche and Spark Therapeutics will be conducting preclinical, clinical and commercialization activities for gene therapy product candidates using the novel caps...
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
October 14, 2020
Lead Product(s) : AAV vectors based gene therapies
Therapeutic Area : Neurology
Highest Development Status : Discovery Platform
Sponsor : F. Hoffmann-La Roche
Deal Size : $1,800.0 million
Deal Type : Collaboration
Lead Product(s) : Synthetic AAV capsids Proteins
Therapeutic Area : Immunology
Study Phase : Discovery
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The presentation will highlight results from Dyno's study on Artificial intelligence powered design of synthetic AAV capsids without pre-existing immunity for the universal treatment of all patients.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
May 12, 2020
Lead Product(s) : Synthetic AAV capsids Proteins
Therapeutic Area : Immunology
Highest Development Status : Discovery
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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