Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AZD5004
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : AstraZeneca
Deal Size : $2,010.0 million
Deal Type : Licensing Agreement
Eccogene Earns $60M Milestone from AstraZeneca for Obesity, Diabetes Drug
Details : AstraZeneca has licensed global rights to ECC5004/AZD5004 from Eccogene. ECC5004 is currently undergoing mid-stage clinical trials for the treatment of obesity and Type 2 diabetes.
Brand Name : ECC5004
Molecule Type : Small molecule
Upfront Cash : $185.0 million
October 23, 2024
Lead Product(s) : AZD5004
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : AstraZeneca
Deal Size : $2,010.0 million
Deal Type : Licensing Agreement
Lead Product(s) : ECC5004
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : AstraZeneca
Deal Size : $2,010.0 million
Deal Type : Licensing Agreement
Details : AstraZeneca will receive an exclusive license to develop and commercialize ECC5004, a small molecule GLP-1 receptor agonist, for the potential treatment of obesity, type-2 diabetes and other comorbidities, in all territories except China.
Brand Name : ECC5004
Molecule Type : Small molecule
Upfront Cash : $185.0 million
November 09, 2023
Lead Product(s) : ECC5004
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : AstraZeneca
Deal Size : $2,010.0 million
Deal Type : Licensing Agreement
Lead Product(s) : ECC5004
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : New Alliance Capital
Deal Size : $25.1 million
Deal Type : Series B Financing
Details : The proceeds will support the development of Eccogene’s clinical-stage programs including Phase I trial of ECC5004, a small molecule GLP-1 receptor agonist for obesity and type 2 diabetes, and the Phase I trial of ECC4703, a THRb full agonist for NASH ...
Brand Name : ECC5004
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 12, 2023
Lead Product(s) : ECC5004
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : New Alliance Capital
Deal Size : $25.1 million
Deal Type : Series B Financing
Lead Product(s) : ECC4703
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eccogene Announces US IND Approval for THRβ Agonist ECC4703
Details : ECC4703 was discovered from Eccogene's internal drug discovery platform. It is a β-selective, liver targeting THR full agonist. ECC4703 has demonstrated superiority in pre-clinical studies over partial agonist MGL-3196.
Brand Name : ECC4703
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 01, 2022
Lead Product(s) : ECC4703
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ECC0509
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eccogene Announces Completed First-in-human of ECC0509 in Phase 1a Clinical Trial in Australia
Details : The trial is a Phase 1, randomized, double-blind, placebo-controlled, sequential single- and multiple ascending dose clinical trial to evaluate the safety, pharmacokinetics, pharmacodynamics of ECC0509 in healthy volunteers.
Brand Name : ECC0509
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 28, 2021
Lead Product(s) : ECC0509
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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