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                          01

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : HK inno.N gains exclusive rights for XW003 (ecnoglutide), a GLP-1 analog, in Korea; Sciwind retains rights in other global markets.

                          Brand Name : XW003

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          May 07, 2024

                          Lead Product(s) : Ecnoglutide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase III

                          Sponsor : HK inno.N

                          Deal Size : $56.0 million

                          Deal Type : Licensing Agreement

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                          02

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : XW004 (ecnoglutide) is a long-acting, cAMP signaling biased, glucagon-like peptide-1 (GLP-1) analog. It is under phase 1 clinical development for the treatment of type 2 diabetes and obesity.

                          Brand Name : XW004

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          January 23, 2024

                          Lead Product(s) : Ecnoglutide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : XW003 (ecnoglutide) is a long-acting GLP-1 analogue in phase 3 trials for improved biological activity in treating type 2 diabetes.

                          Brand Name : XW003

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 02, 2024

                          Lead Product(s) : Ecnoglutide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : XW003 (ecnoglutide) is a novel, biased long-acting GLP-1 peptide analogue optimized for improved biological activity. GLP-1 analogs are effective therapies in managing type 2 diabetes, obesity, and have demonstrated clinical potential as a treatment for ...

                          Brand Name : XW003

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          January 30, 2023

                          Lead Product(s) : Ecnoglutide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : After 14 weeks of treatment, participants receiving 1.8 mg and 2.4 mg XW003 (ecnoglutide) achieved statistically significant mean body weight loss of 8.32 kg (9.6%) and 7.27 kg (9.0%), respectively, compared to 0.62 kg (0.9%) for those receiving placebo ...

                          Brand Name : XW003

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          August 08, 2022

                          Lead Product(s) : Ecnoglutide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : At week 20, participants receiving 0.4 mg, 0.8 mg, and 1.2 mg XW003 (ecnoglutide) had statistically significant HbA1c reductions from baseline of 1.8%, 1.9% and 2.4%, respectively, compared to 0.5% in participants receiving placebo (P < 0.0001).

                          Brand Name : XW003

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          August 02, 2022

                          Lead Product(s) : Ecnoglutide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : XW004 is an oral tablet formulation of Ecnoglutide, a novel long-lasting GLP-1 peptide analogue under development for the treatment of obesity, type 2 diabetes and NASH.

                          Brand Name : XW004

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          April 13, 2022

                          Lead Product(s) : Ecnoglutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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