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    [{"orgOrder":0,"company":"Infinity Pharmaceuticals","sponsor":"BVF Partners","pharmaFlowCategory":"D","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Financing","leadProduct":"Eganelisib","moa":"||PI3K gamma","graph1":"Rare Diseases and Disorders","graph2":"Phase II","graph3":"Infinity Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Infinity Pharmaceuticals \/ BVF Partners","highestDevelopmentStatusID":"8","companyTruncated":"Infinity Pharmaceuticals \/ BVF Partners"},{"orgOrder":0,"company":"Infinity Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Eganelisib","moa":"||PI3K gamma","graph1":"Oncology","graph2":"Phase II","graph3":"Infinity 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Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Eganelisib","moa":"||PI3K gamma","graph1":"Oncology","graph2":"Phase II","graph3":"Infinity Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Infinity Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Infinity Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Infinity Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Eganelisib","moa":"||PI3K gamma","graph1":"Oncology","graph2":"Phase II","graph3":"Infinity Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph 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    Find Clinical Drug Pipeline Developments & Deals for Eganelisib

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                            01

                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : MEI Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals Provides Additional Information on MARIO-8 Study Evaluating Eganelisib in Combination...

                            Details : IPI-549 (eganelisib) is a first-in-class, oral, once-daily, immuno-oncology candidate that selectively inhibits phosphoinositide-3-kinase gamma, which is investigated in Combination with Pembrolizumab in Patients with Squamous Cell Cancer of the Head and...

                            Product Name : IPI-549

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 07, 2023

                            Lead Product(s) : Eganelisib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : MEI Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : MEI Pharma

                            Deal Size : Undisclosed

                            Deal Type : Termination

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals Announces Termination of Merger Agreement with MEI Pharma

                            Details : Under the termination, Infinity has continued to prepare for the initiation of a planned global Phase 2 clinical trial evaluating IPI-549 (eganelisib) in head and neck squamous cell carcinoma.

                            Product Name : IPI-549

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            July 24, 2023

                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : MEI Pharma

                            Deal Size : Undisclosed

                            Deal Type : Termination

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                            03

                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : MEI Pharma

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            MEI Pharma and Infinity Pharmaceuticals Announce Definitive Merger Agreement to Advance Three Promising Clinic...

                            Details : The Combination will create a company with a diverse product development pipeline led by a planned new global Phase 2 clinical trial evaluating IPI-549 (eganelisib) in head and neck squamous cell carcinoma (HNSCC)

                            Product Name : IPI-549

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            February 23, 2023

                            Lead Product(s) : Eganelisib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : MEI Pharma

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            04

                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals Outlines Eganelisib Clinical Development Strategy and Provides 2022 Guidance

                            Details : IPI-54 (Eganelisb) in combination therapy has demonstrated positive resutls total tumor volume reduction is 92.8% and 85.2%, and disease control rates is 92.8% and 81.4%, in PD-L1 frontline TNBC patients.

                            Product Name : IPI-549

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 01, 2022

                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Infinity Pharmaceuticals

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                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Piper Sandler

                            Deal Size : $80.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Infinity Announces Pricing of $80 Million Public Offering of Common Stock

                            Details : Infinity intends to use net proceeds from the offering for the continued clinical development of eganelisib, for general corporate purposes and for working capital.

                            Product Name : IPI-549

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 02, 2021

                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Piper Sandler

                            Deal Size : $80.0 million

                            Deal Type : Public Offering

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                            06

                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals Presents Data from Phase 2 MARIO-275 Trial of Eganelisib and Nivolumab in Advanced Ur...

                            Details : The objective of MARIO-275 was to address the need for better treatments for second line (2L) advanced UC patients. Combination of eganelisib with nivolumab demonstrated improved ORR, DCR, and PFS versus 2L standard of care nivolumab monotherapy.

                            Product Name : IPI-549

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 02, 2021

                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Infinity Pharmaceuticals

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                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Encouraging Updated Data from Phase 2 MARIO-3 TNBC Trial Presented at 2021 San Antonio Breast Cancer Symposium

                            Details : IPI-549 (eganelisib ), a first-in-class, oral, immuno-oncology macrophage reprogramming therapeutic addresses a fundamental biologic mechanism of immune suppression in cancer in multiple clinical studies.

                            Product Name : IPI-549

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 12, 2021

                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals Presents Updated Data from Phase 2 MARIO-275 Trial

                            Details : At the one-year landmark, 59% of patients in the ITT population receiving the eganelisib plus nivolumab combination remained alive, compared to 32% in the nivolumab control arm.

                            Product Name : IPI-549

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 27, 2021

                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals Hosting Webinar on MARIO-3 and MARIO-275 Phase 2 Trials

                            Details : MARIO-3 is a Phase 2 triplet combination study evaluating the addition of eganelisib to the approved standard of care combination of Tecentriq® and Abraxane® in the front-line setting in TNBC.

                            Product Name : IPI-549

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 20, 2021

                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Infinity Pharmaceuticals

                            U.S.A arrow
                            Spring Meeting
                            Not Confirmed

                            Infinity Pharmaceuticals

                            U.S.A arrow
                            Spring Meeting
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Arcus Biosciences

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Infinity to Present at The Keystone Symposia Precision Oncology Meeting

                            Details : In collaboration with Arcus Biosciences, Infinity is evaluating a checkpoint inhibitor-free, novel combination regimen of eganelisib plus etrumadenant (AB928, a dual adenosine receptor antagonist) plus Doxil® in advanced TNBC patients.

                            Product Name : IPI-549

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 14, 2021

                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Arcus Biosciences

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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