Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Yosemite Capital
Deal Size : $64.0 million
Deal Type : Private Placement
Lomond Therapeutics Completes Second and Third Closings and Adds Two New Investors
Details : The net proceeds from the placement will used to fund the clincial development of ZE46-0134 (lomonitinib), which is being evaluated for the treatment of AML.
Product Name : ZE46-0134
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 28, 2025
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Yosemite Capital
Deal Size : $64.0 million
Deal Type : Private Placement
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Deerfield Management Company
Deal Size : $44.0 million
Deal Type : Private Placement
Lomond Therapeutics Completes Reverse Merger and Closes $44 Million Private Placement
Details : The net proceeds from the placement will used to fund the clincial development of ZE46-0134 (lomonitinib), which is being evaluated for the treatment of AML.
Product Name : ZE46-0134
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
November 04, 2024
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Deerfield Management Company
Deal Size : $44.0 million
Deal Type : Private Placement
Lead Product(s) : Balamenib
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Eilean Approved to Initiate Trial with Balamenib, a Best-in-Class Menin Inhibitor
Details : ZE63-0302 (balamenib) is a selective best-in-class oral small molecule inhibitor of the menin-KMT2A interaction. It is being evaluated for the treatment of hematological malignancies.
Product Name : ZE63-0302
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 03, 2024
Lead Product(s) : Balamenib
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lonitoclax
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lomond’s Lonitoclax IND Cleared by FDA for Chronic Lymphocytic Leukemia
Details : Lonitoclax has a best-in-class potency and selectivity against BCL-2. Currently, it is being evaluated for the treatment of chronic lymphocytic leukemia.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 15, 2024
Lead Product(s) : Lonitoclax
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Eilean Receives Clearance to Initiate R/R AML Trial with Lomonitinib
Details : ZE46-0134 (lomonitinib) is a potent and selective inhibitor of FLT3 ITD, TKD, and other FLT3 mutations, as well as IRAK4, under investigation for relapsed/refractory acute myeloid leukemia.
Product Name : ZE46-0134
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 04, 2024
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Expert Systems Celebrates Fast-Tracked Human Dosing Start for Eiletoclax in Just 3 Years
Details : ZE50-0134 (eiletoclax) is a selective BCL2 inhibitor, which is being evaluated for the treatment of chronic lymphocytic leukemia & acute myeloid leukemia.
Product Name : ZE50-0134
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 21, 2024
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Eilean Therapeutics Completes Studies and Begins Multiple Dosing Of Lomonitinib
Details : ZE46-0134 (lomonitinib) is a potent, selective pan-FLT3/IRAK4 inhibitor currently being tested in phase 1 trials for FLT3-mutated Acute Myeloid Leukemia.
Product Name : ZE46-0134
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 29, 2024
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Eilean Initiates Human Trial for Eiletoclax, a Bcl2 Inhibitor with Safety Improvements
Details : ZE50-0134 (eiletoclax) is a highly potent and selective BCL2 inhibitor. It is being evaluated in phase 1 tirals for the treatment of acute myeloid leukemia & chronic lymphocytic leukemia.
Product Name : ZE50-0134
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 29, 2024
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ZE46-0134, a highly potent and selective pan-FLT3 inhibitor that targets clinically relevant FLT3 mutations including the FLT3 gatekeeper mutation, while sparing the wild type form of the protein.
Product Name : ZE46-0134
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 21, 2023
Lead Product(s) : Lomonitinib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable