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    [{"orgOrder":0,"company":"Eilean Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"ZE46-0134","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Eilean Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Eilean Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Eilean Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Eilean Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Eiletoclax","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Eilean Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Eilean Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Eilean Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Eilean Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Lomonitinib","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Eilean Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Eilean Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Eilean Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Eilean Therapeutics","sponsor":"Expert Systems","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Undisclosed","year":"2024","type":"Partnership","leadProduct":"Undisclosed","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Eilean Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Eilean Therapeutics \/ Eilean Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Eilean Therapeutics \/ Eilean Therapeutics"},{"orgOrder":0,"company":"Eilean Therapeutics","sponsor":"Expert Systems","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Eiletoclax","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Eilean Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Eilean Therapeutics \/ Expert Systems","highestDevelopmentStatusID":"6","companyTruncated":"Eilean Therapeutics \/ Expert Systems"},{"orgOrder":0,"company":"Eilean Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Balamenib","moa":"","graph1":"Oncology","graph2":"IND Enabling","graph3":"Eilean Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Eilean Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"Eilean Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Eilean Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Lomonitinib","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Eilean Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Eilean Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Eilean Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Lomond Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Lonitoclax","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Lomond Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Lomond Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Lomond Therapeutics \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Eilean Therapeutics

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                            01

                            Lomond Therapeutics

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                            Fi Europe 2024
                            Not Confirmed

                            Lomond Therapeutics

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                            Lead Product(s) : Lonitoclax

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Lomond’s Lonitoclax IND Cleared by FDA for Chronic Lymphocytic Leukemia

                            Details : Lonitoclax has a best-in-class potency and selectivity against BCL-2. Currently, it is being evaluated for the treatment of chronic lymphocytic leukemia.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 15, 2024

                            Lead Product(s) : Lonitoclax

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Eilean Therapeutics

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                            Fi Europe 2024
                            Not Confirmed

                            Eilean Therapeutics

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                            Fi Europe 2024
                            Not Confirmed
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                            Lead Product(s) : Lomonitinib

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Eilean Receives Clearance to Initiate R/R AML Trial with Lomonitinib

                            Details : ZE46-0134 (lomonitinib) is a potent and selective inhibitor of FLT3 ITD, TKD, and other FLT3 mutations, as well as IRAK4, under investigation for relapsed/refractory acute myeloid leukemia.

                            Brand Name : ZE46-0134

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 04, 2024

                            Lead Product(s) : Lomonitinib

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Eilean Therapeutics

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                            Fi Europe 2024
                            Not Confirmed

                            Eilean Therapeutics

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                            Fi Europe 2024
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Expert Systems

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Expert Systems Expands Partnership with Eilean Therapeutics for PTPN2 Inhibitor Program

                            Details : The partnership aims to support the clinical advancement of Eilean's lead PTPN2 inhibitor, which is being evaluated in the preclinical trial studies for the treatment of patients related to neoplasms.

                            Brand Name : Undisclosed

                            Molecule Type : Undisclosed

                            Upfront Cash : Undisclosed

                            March 12, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Expert Systems

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            04

                            Eilean Therapeutics

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                            Fi Europe 2024
                            Not Confirmed

                            Eilean Therapeutics

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                            Fi Europe 2024
                            Not Confirmed
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                            Lead Product(s) : Balamenib

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Eilean Approved to Initiate Trial with Balamenib, a Best-in-Class Menin Inhibitor

                            Details : ZE63-0302 (balamenib) is a selective best-in-class oral small molecule inhibitor of the menin-KMT2A interaction. It is being evaluated for the treatment of hematological malignancies.

                            Brand Name : ZE63-0302

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 11, 2024

                            Lead Product(s) : Balamenib

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Eilean Therapeutics

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                            Fi Europe 2024
                            Not Confirmed

                            Eilean Therapeutics

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                            Fi Europe 2024
                            Not Confirmed
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                            Lead Product(s) : Eiletoclax

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Expert Systems

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Expert Systems Celebrates Fast-Tracked Human Dosing Start for Eiletoclax in Just 3 Years

                            Details : ZE50-0134 (eiletoclax) is a selective BCL2 inhibitor, which is being evaluated for the treatment of chronic lymphocytic leukemia & acute myeloid leukemia.

                            Brand Name : ZE50-0134

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 21, 2024

                            Lead Product(s) : Eiletoclax

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Expert Systems

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Eilean Therapeutics

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                            Fi Europe 2024
                            Not Confirmed

                            Eilean Therapeutics

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                            Lead Product(s) : Eiletoclax

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Eilean Initiates Human Trial for Eiletoclax, a Bcl2 Inhibitor with Safety Improvements

                            Details : ZE50-0134 (eiletoclax) is a highly potent and selective BCL2 inhibitor. It is being evaluated in phase 1 tirals for the treatment of acute myeloid leukemia & chronic lymphocytic leukemia.

                            Brand Name : ZE50-0134

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 29, 2024

                            Lead Product(s) : Eiletoclax

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Eilean Therapeutics

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                            Fi Europe 2024
                            Not Confirmed

                            Eilean Therapeutics

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                            Fi Europe 2024
                            Not Confirmed
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                            Lead Product(s) : Lomonitinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Eilean Therapeutics Completes Studies and Begins Multiple Dosing Of Lomonitinib

                            Details : ZE46-0134 (lomonitinib) is a potent, selective pan-FLT3/IRAK4 inhibitor currently being tested in phase 1 trials for FLT3-mutated Acute Myeloid Leukemia.

                            Brand Name : ZE46-0134

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 29, 2024

                            Lead Product(s) : Lomonitinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Eilean Therapeutics

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                            Fi Europe 2024
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                            Eilean Therapeutics

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                            Lead Product(s) : ZE46-0134

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Eilean Therapeutics Doses First Patient with ZE46-0134, A Selective FLT3WT-Sparing, Pan FLT3Mut Inhibitor

                            Details : ZE46-0134, a highly potent and selective pan-FLT3 inhibitor that targets clinically relevant FLT3 mutations including the FLT3 gatekeeper mutation, while sparing the wild type form of the protein.

                            Brand Name : ZE46-0134

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 21, 2023

                            Lead Product(s) : ZE46-0134

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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